How precisely does circuit wiring specify function? This fundamental question is particularly relevant for modern neuroscience, as large-scale electron microscopy now enables the reconstruction of neural circuits at single-synapse resolution across many organisms. To interpret circuit function from such datasets, we must understand the extent to which the measured structure constrains dynamics. We investigate this question in the Drosophila head direction (HD) circuit, which maintains an internal heading estimate through attractor dynamics that integrate self-motion velocity cues. This circuit serves as a sensitive assay for functional specification: continuous attractor networks are theoretically known to require finely tuned wiring symmetries, whereas connectomes omit key cellular parameters such as synaptic gains, neuronal thresholds, and time constants, and reveal that biological wiring can be heterogeneous. We introduce a method that combines selfsupervised and unsupervised learning objectives to estimate unknown parameters at the level of cell types, rather than individual neurons and synapses. Starting from the raw connectivity matrix, our approach recovers a network that exhibits continuous attractor dynamics and accurately integrates a range of velocity inputs, despite minimal parameter tuning on a connectome that notably departs from the symmetric regularity of an idealized ring attractor. We characterize how deviations from the original connectome shape the space of viable solutions. We also perform in-silico ablation experiments to probe the distinct functional roles of specific cell types in the circuit, demonstrating how connectome-derived structure, when augmented with minimal, biologically grounded tuning, can replicate known physiology and elucidate circuit function.

The biggerµ is,thebetter the error correction. For the set of( x) that form a group, a matrix representationM( x) is equivalent to another representation M( x)if there exists an invertible matrixP such that M( x)=PM( x)P 1 for each x. A matrix representation is reducible if it is equivalent to a block diagonal matrix representation, i.e., we can find a matrixP, such thatPM( x)P 1 is block diagonal for every x. IfM is block-diagonal,M =diag(Mk,k=1,...,K), with nonequivalentblocks,andeachblock Mkcannotbefurtherreduced,thenthematrixelements (Mkij( x)) are orthogonal basis functions of x. Such orthogonality relations are proved by Schur [15] for finite group, and by Peter-Weyl for compact Lie group [13].

Qubit control protocols have traditionally leveraged a characterisation of the qubit-bath coupling via its power spectral density. Previous work proposed the inference of noise operators that characterise the influence of a classical bath using a grey-box approach that combines deep neural networks with physics-encoded layers. This overall structure is complex and poses challenges in scaling and real-time operations. Here, we show that no expensive neural networks are needed and that this noise operator description admits an efficient parameterisation. We refer to the resulting parameter space as the \textit{quantum feature space} of the qubit dynamics resulting from the coupled bath. We show that the Euclidean distance defined over the quantum feature space provides an effective method for classifying noise processes in the presence of a given set of controls. Using the quantum feature space as the input space for a simple machine learning algorithm (random forest, in this case), we demonstrate that it can effectively classify the stationarity and the broad class of noise processes perturbing a qubit. Finally, we explore how control pulse parameters map to the quantum feature space.

In this paper, we extend our previous work on the Expressive Neural Network (ENN), a multilayer perceptron with adaptive activation functions parametrized using the Discrete Cosine Transform (DCT). Building upon previous work that demonstrated the strong expressiveness of ENNs with compact architectures, we now emphasize their efficiency, interpretability and pruning capabilities. The DCT-based parameterization provides a structured and decorrelated representation that reveals the functional role of each neuron and allows direct identification of redundant components. Leveraging this property, we propose an efficient pruning strategy that removes unnecessary DCT coefficients with negligible or no loss in performance. Experimental results across classification and implicit neural representation tasks confirm that ENNs achieve state-of-the-art accuracy while maintaining a low number of parameters. Furthermore, up to 40% of the activation coefficients can be safely pruned, thanks to the orthogonality and bounded nature of the DCT basis. Overall, these findings demonstrate that the ENN framework offers a principled integration of signal processing concepts into neural network design, achieving a balanced trade-off between expressiveness, compactness, and interpretability.

The dynamics of neural activity are described by a standard rate model. Note that only the third term of Eq. 'th place cell preferred firing position in the's are standard unit vectors spanning an orthonormal basis. To derive Eq. 3 we evaluate the derivative of Energy landscapes were uniformly shifted throughout the manuscript by a constant (Figs. For each network with a different number of total embedded maps, 15 realizations were performed in which the permutations between the spatial maps were chosen independently and at random. Code availability Code is available at public repository https://doi.org/10.5281/zenodo.10016179.

To extract motion information, the brain needs to compensate for time delays that are ubiquitous in neural signal transmission and processing. Here we propose a simple yet effective mechanism to implement anticipative tracking in neural systems. The proposed mechanism utilizes the property of spike-frequency adaptation (SFA), a feature widely observed in neuronal responses. We employ continuous attractor neural networks (CANNs) as the model to describe the tracking behaviors in neural systems. Incorporating SFA, a CANN exhibits intrinsic mobility, manifested by the ability of the CANN to support self-sustained travelling waves. In tracking a moving stimulus, the interplay between the external drive and the intrinsic mobility of the network determines the tracking performance. Interestingly, we find that the regime of anticipation effectively coincides with the regime where the intrinsic speed of the travelling wave exceeds that of the external drive. Depending on the SFA amplitudes, the network can achieve either perfect tracking, with zero-lag to the input, or perfect anticipative tracking, with a constant leading time to the input. Our model successfully reproduces experimentally observed anticipative tracking behaviors, and sheds light on our understanding of how the brain processes motion information in a timely manner.