Sleep apnea, a prevalent sleep disorder, involves repeated episodes of breathing interruptions during sleep, leading to various health complications, including cognitive impairments, high blood pressure, heart disease, stroke, and even death. One of the main challenges in diagnosing and treating sleep apnea is identifying individuals at risk. The current gold standard for diagnosis, Polysomnography (PSG), is costly, labor intensive, and inconvenient, often resulting in poor quality sleep data. This paper presents a novel approach to the detection of sleep apnea using a Convolutional Neural Network (CNN) trained on single channel EEG data. The proposed CNN achieved an accuracy of 85.1% and a Matthews Correlation Coefficient (MCC) of 0.22, demonstrating a significant potential for home based applications by addressing the limitations of PSG in automated sleep apnea detection. Key contributions of this work also include the development of a comprehensive preprocessing pipeline with an Infinite Impulse Response (IIR) Butterworth filter, a dataset construction method providing broader temporal context, and the application of SMOTETomek to address class imbalance. This research underscores the feasibility of transitioning from traditional laboratory based diagnostics to more accessible, automated home based solutions, improving patient outcomes and broadening the accessibility of sleep disorder diagnostics.

Continuous monitoring and accurate detection of complex sleep patterns associated to different sleep-related conditions is essential, not only for enhancing sleep quality but also for preventing the risk of developing chronic illnesses associated to unhealthy sleep. Despite significant advances in research, achieving versatile recognition of various unhealthy and sub-healthy sleep patterns with simple wearable devices at home remains a significant challenge. Here, we report a robust and durable ultrasensitive strain sensor array printed on a smart garment, in its collar region. This solution allows detecting subtle vibrations associated with multiple sleep patterns at the extrinsic laryngeal muscles. Equipped with a deep learning neural network, it can precisely identify six sleep states-nasal breathing, mouth breathing, snoring, bruxism, central sleep apnea (CSA), and obstructive sleep apnea (OSA)-with an impressive accuracy of 98.6%, all without requiring specific positioning. We further demonstrate its explainability and generalization capabilities in practical applications. Explainable artificial intelligence (XAI) visualizations reflect comprehensive signal pattern analysis with low bias. Transfer learning tests show that the system can achieve high accuracy (overall accuracy of 95%) on new users with very few-shot learning (less than 15 samples per class). The scalable manufacturing process, robustness, high accuracy, and excellent generalization of the smart garment make it a promising tool for next-generation continuous sleep monitoring.

Several therapy routines require deep breathing exercises as a key component and patients undergoing such therapies must perform these exercises regularly. Assessing the outcome of a therapy and tailoring its course necessitates monitoring a patient's compliance with the therapy. While therapy compliance monitoring is routine in a clinical environment, it is challenging to do in an at-home setting. This is so because a home setting lacks access to specialized equipment and skilled professionals needed to effectively monitor the performance of a therapy routine by a patient. For some types of therapies, these challenges can be addressed with the use of consumer-grade hardware, such as earphones and smartphones, as practical solutions. To accurately monitor breathing exercises using wireless earphones, this paper proposes a framework that has the potential for assessing a patient's compliance with an at-home therapy. The proposed system performs real-time detection of breathing phases and channels with high accuracy by processing a $\mathbf{500}$ ms audio signal through two convolutional neural networks. The first network, called a channel classifier, distinguishes between nasal and oral breathing, and a pause. The second network, called a phase classifier, determines whether the audio segment is from inhalation or exhalation. According to $k$-fold cross-validation, the channel and phase classifiers achieved a maximum F1 score of $\mathbf{97.99\%}$ and $\mathbf{89.46\%}$, respectively. The results demonstrate the potential of using commodity earphones for real-time breathing channel and phase detection for breathing therapy compliance monitoring.

Electronic patient records (EPRs) produce a wealth of data but contain significant missing information. Understanding and handling this missing data is an important part of clinical data analysis and if left unaddressed could result in bias in analysis and distortion in critical conclusions. Missing data may be linked to health care professional practice patterns and imputation of missing data can increase the validity of clinical decisions. This study focuses on statistical approaches for understanding and interpreting the missing data and machine learning based clinical data imputation using a single centre's paediatric emergency data and the data from UK's largest clinical audit for traumatic injury database (TARN). In the study of 56,961 data points related to initial vital signs and observations taken on children presenting to an Emergency Department, we have shown that missing data are likely to be non-random and how these are linked to health care professional practice patterns. We have then examined 79 TARN fields with missing values for 5,791 trauma cases. Singular Value Decomposition (SVD) and k-Nearest Neighbour (kNN) based missing data imputation methods are used and imputation results against the original dataset are compared and statistically tested. We have concluded that the 1NN imputer is the best imputation which indicates a usual pattern of clinical decision making: find the most similar patients and take their attributes as imputation.

Human respiratory rate and its pattern convey essential information about the physical and psychological states of the subject. Abnormal breathing can indicate fatal health issues leading to further diagnosis and treatment. Wireless light-wave sensing (LWS) using incoherent infrared light shows promise in safe, discreet, efficient, and non-invasive human breathing monitoring without raising privacy concerns. The respiration monitoring system needs to be trained on different types of breathing patterns to identify breathing anomalies.The system must also validate the collected data as a breathing waveform, discarding any faulty data caused by external interruption, user movement, or system malfunction. To address these needs, this study simulated normal and different types of abnormal respiration using a robot that mimics human breathing patterns. Then, time-series respiration data were collected using infrared light-wave sensing technology. Three machine learning algorithms, decision tree, random forest and XGBoost, were applied to detect breathing anomalies and faulty data. Model performances were evaluated through cross-validation, assessing classification accuracy, precision and recall scores. The random forest model achieved the highest classification accuracy of 96.75% with data collected at a 0.5m distance. In general, ensemble models like random forest and XGBoost performed better than a single model in classifying the data collected at multiple distances from the light-wave sensing setup.

In this study, we present a deep learning-based approach for time-series respiration data classification. The dataset contains regular breathing patterns as well as various forms of abnormal breathing, obtained through non-contact incoherent light-wave sensing (LWS) technology. Given the one-dimensional (1D) nature of the data, we employed a 1D convolutional neural network (1D-CNN) for classification purposes. Genetic algorithm was employed to optimize the 1D-CNN architecture to maximize classification accuracy. Addressing the computational complexity associated with training the 1D-CNN across multiple generations, we implemented transfer learning from a pre-trained model. This approach significantly reduced the computational time required for training, thereby enhancing the efficiency of the optimization process. This study contributes valuable insights into the potential applications of deep learning methodologies for enhancing respiratory anomaly detection through precise and efficient respiration classification.

People can learn to control a robotic third arm using their eyes and chest muscles. Such extra limbs could become essential tools for surgeons or people working in industrial jobs, say researchers. Giulia Dominijanni at the Swiss Federal Institute of Technology Lausanne and her colleagues created real robotic third arms and virtual ones inside VR environments, all controlled by a combination of eye movements and diaphragm contractions. In tests, 65 volunteers were able to successfully carry out a range of tasks without interfering with their normal breathing, speech or vision. Unlike prosthetics for people with amputated limbs, which can attach to a stump and use existing nerve connections to the brain, augmented devices require entirely new connections and are therefore more difficult to engineer, says Dominijanni.

In this study, we present a non-contact respiratory anomaly detection method using incoherent light-wave signals reflected from the chest of a mechanical robot that can breathe like human beings. In comparison to existing radar and camera-based sensing systems for vitals monitoring, this technology uses only a low-cost ubiquitous light source (e.g., infrared light emitting diode) and sensor (e.g., photodetector). This light-wave sensing (LWS) system recognizes different breathing anomalies from the variations of light intensity reflected from the chest of the robot within a 0.5m-1.5m range. The anomaly detection model demonstrates up to 96.6% average accuracy in classifying 7 different types of breathing data using machine learning. The model can also detect faulty data collected by the system that does not contain breathing information. The developed system can be utilized at home or healthcare facilities as a smart, non-contact and discreet respiration monitoring method.

This paper addresses a regression problem in which output label values are the results of sensing the magnitude of a phenomenon. A low value of such labels can mean either that the actual magnitude of the phenomenon was low or that the sensor made an incomplete observation. This leads to a bias toward lower values in labels and the resultant learning because labels may have lower values due to incomplete observations, even if the actual magnitude of the phenomenon was high. Moreover, because an incomplete observation does not provide any tags indicating incompleteness, we cannot eliminate or impute them. To address this issue, we propose a learning algorithm that explicitly models incomplete observations corrupted with an asymmetric noise that always has a negative value. We show that our algorithm is unbiased as if it were learned from uncorrupted data that does not involve incomplete observations. We demonstrate the advantages of our algorithm through numerical experiments.

Respiratory chest belt sensor can be used to measure the respiratory rate and other respiratory health parameters. Virtual Respiratory Belt, VRB, algorithms estimate the belt sensor waveform from speech audio. In this paper we compare the detection of inspiration events (IE) from respiratory belt sensor data using a novel neural VRB algorithm and the detections based on time-aligned linguistic content. The results show the superiority of the VRB method over word pause detection or grammatical content segmentation. The comparison of the methods show that both read and spontaneous speech content has a significant amount of ungrammatical breathing, that is, breathing events that are not aligned with grammatically appropriate places in language. This study gives new insights into the development of VRB methods and adds to the general understanding of speech breathing behavior. Moreover, a new VRB method, VRBOLA, for the reconstruction of the continuous breathing waveform is demonstrated.