Achieving robust and personalized performance in neuro-steered Target Speaker Extraction (TSE) remains a significant challenge for next-generation hearing aids. This is primarily due to two factors: the inherent non-stationarity of EEG signals across sessions, and the high inter-subject variability that limits the efficacy of generalized models. To address these issues, we propose Brainprint-Modulated Target Speaker Extraction (BM-TSE), a novel framework for personalized and high-fidelity extraction. BM-TSE first employs a spatio-temporal EEG encoder with an Adaptive Spectral Gain (ASG) module to extract stable features resilient to non-stationarity. The core of our framework is a personalized modulation mechanism, where a unified brainmap embedding is learned under the joint supervision of subject identification (SID) and auditory attention decoding (AAD) tasks. This learned brainmap, encoding both static user traits and dynamic attentional states, actively refines the audio separation process, dynamically tailoring the output to each user. Evaluations on the public KUL and Cocktail Party datasets demonstrate that BM-TSE achieves state-of-the-art performance, significantly outperforming existing methods. Our code is publicly accessible at: https://github.com/rosshan-orz/BM-TSE.

Recent years have seen a surge in research focused on leveraging graph learning techniques to detect neurodegenerative diseases. However, existing graph-based approaches typically lack the ability to localize and extract the specific brain regions driving neurodegenerative pathology within the full connectome. Additionally, recent works on multimodal brain graph models often suffer from high computational complexity, limiting their practical use in resource-constrained devices. In this study, we present BrainMAP, a novel multimodal graph learning framework designed for precise and computationally efficient identification of brain regions affected by neurodegenerative diseases. First, BrainMAP utilizes an atlas-driven filtering approach guided by the AAL atlas to pinpoint and extract critical brain subgraphs. Unlike recent state-of-the-art methods, which model the entire brain network, BrainMAP achieves more than 50% reduction in computational overhead by concentrating on disease-relevant subgraphs. Second, we employ an advanced multimodal fusion process comprising cross-node attention to align functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) data, coupled with an adaptive gating mechanism to blend and integrate these modalities dynamically. Experimental results demonstrate that BrainMAP outperforms state-of-the-art methods in computational efficiency, without compromising predictive accuracy.

Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain activity, Graph Neural Networks (GNNs) have been widely applied to the analysis of functional connectivities (FC) derived from fMRI data, due to their ability to capture the synergistic interactions among brain regions. However, in the human brain, performing complex tasks typically involves the activation of certain pathways, which could be represented as paths across graphs. As such, conventional GNNs struggle to learn from these pathways due to the long-range dependencies of multiple pathways. To address these challenges, we introduce a novel framework BrainMAP to learn Multiple Activation Pathways in Brain networks. BrainMAP leverages sequential models to identify long-range correlations among sequentialized brain regions and incorporates an aggregation module based on Mixture of Experts (MoE) to learn from multiple pathways. Our comprehensive experiments highlight BrainMAP's superior performance. Furthermore, our framework enables explanatory analyses of crucial brain regions involved in tasks. Our code is provided at https://github.com/LzyFischer/Graph-Mamba.