Knowledge graphs, a powerful tool for structuring information through relational triplets, have recently become the new front-runner in enhancing question-answering systems. While traditional Retrieval Augmented Generation (RAG) approaches are proficient in fact-based and local context-based extraction from concise texts, they encounter limitations when addressing the thematic and holistic understanding of complex, extensive texts, requiring a deeper analysis of both text and context. This paper presents a comprehensive technical comparative study of three different methodologies for constructing knowledge graph triplets and integrating them with Large Language Models (LLMs) for question answering: spaCy, Stanford CoreNLP-OpenIE, and GraphRAG, all leveraging open source technologies. We evaluate the effectiveness, feasibility, and adaptability of these methods by analyzing their capabilities, state of development, and their impact on the performance of LLM-based question answering. Experimental results indicate that while OpenIE provides the most comprehensive coverage of triplets, GraphRAG demonstrates superior reasoning abilities among the three. We conclude with a discussion on the strengths and limitations of each method and provide insights into future directions for improving knowledge graph-based question answering.

Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency. However, AI tools are susceptible to domain shift, where a significant drop in performance can occur due to differences in the training and testing sets, including morphological diversity between organs, species, and variations in staining protocols. Furthermore, the number of mitoses is much less than the count of normal nuclei, which introduces severely imbalanced data for the detection task. In this work, we formulate mitosis detection as a pixel-level segmentation and propose a teacher-student model that simultaneously addresses mitosis detection (Track 1) and atypical mitosis classification (Track 2). Our method is based on a UNet segmentation backbone that integrates domain generalization modules, namely contrastive representation learning and domain-adversarial training. A teacher-student strategy is employed to generate pixel-level pseudo-masks not only for annotated mitoses and hard negatives but also for normal nuclei, thereby enhancing feature discrimination and improving robustness against domain shift. For the classification task, we introduce a multi-scale CNN classifier that leverages feature maps from the segmentation model within a multi-task learning paradigm. On the preliminary test set, the algorithm achieved an F1 score of 0.7660 in Track 1 and balanced accuracy of 0.8414 in Track 2, demonstrating the effectiveness of integrating segmentation-based detection and classification into a unified framework for robust mitosis analysis.

Automated detection and classification of mitotic figures especially distinguishing atypical from normal remain critical challenges in computational pathology. We present MitoDetect++, a unified deep learning pipeline designed for the MIDOG 2025 challenge, addressing both mitosis detection and atypical mitosis classification. For detection (Track 1), we employ a U-Net-based encoder-decoder architecture with EfficientNetV2-L as the backbone, enhanced with attention modules, and trained via combined segmentation losses. For classification (Track 2), we leverage the Virchow2 vision transformer, fine-tuned efficiently using Low-Rank Adaptation (LoRA) to minimize resource consumption. To improve generalization and mitigate domain shifts, we integrate strong augmentations, focal loss, and group-aware stratified 5-fold cross-validation. At inference, we deploy test-time augmentation (TTA) to boost robustness. Our method achieves a balanced accuracy of 0.892 across validation domains, highlighting its clinical applicability and scalability across tasks.

Mitotic figure detection is a crucial task in computational pathology, as mitotic activity serves as a strong prognostic marker for tumor aggressiveness. However, domain variability that arises from differences in scanners, tissue types, and staining protocols poses a major challenge to the robustness of automated detection methods. In this study, we introduce SDF-YOLO (Single Detect Focused YOLO), a lightweight yet domain-robust detection framework designed specifically for small, rare targets such as mitotic figures. The model builds on YOLOv11 with task-specific modifications, including a single detection head aligned with mitotic figure scale, coordinate attention to enhance positional sensitivity, and improved cross-channel feature mixing. Experiments were conducted on three datasets that span human and canine tumors: MIDOG ++, canine cutaneous mast cell tumor (CCMCT), and canine mammary carcinoma (CMC). When submitted to the preliminary test set for the MIDOG2025 challenge, SDF-YOLO achieved an average precision (AP) of 0.799, with a precision of 0.758, a recall of 0.775, an F1 score of 0.766, and an FROC-AUC of 5.793, demonstrating both competitive accuracy and computational efficiency. These results indicate that SDF-YOLO provides a reliable and efficient framework for robust mitotic figure detection across diverse domains.

Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a bag of tricks - that enable robust, real-time MF detection across diverse domains. We build on the efficient RTMDet single stage object detector to achieve high inference speed suitable for clinical deployment. Our method addresses scanner variability and tumor heterogeneity via extensive multi-domain training data, balanced sampling, and careful augmentation. Additionally, we employ targeted, hard negative mining on necrotic and debris tissue to reduce false positives. In a grouped 5-fold cross-validation across multiple MF datasets, our model achieves an F1 score between 0.78 and 0.84. On the preliminary test set of the MItosis DOmain Generalization (MIDOG) 2025 challenge, our single-stage RTMDet-S based approach reaches an F1 of 0.81, outperforming larger models and demonstrating adaptability to new, unfamiliar domains. The proposed solution offers a practical trade-off between accuracy and speed, making it attractive for real-world clinical adoption.

Collectible card games (CCGs) are a difficult genre for AI due to their partial observability, long-term decision-making, and evolving card sets. Due to this, current AI models perform vastly worse than human players at CCG tasks such as deckbuilding and gameplay. In this work, we introduce UrzaGPT, a domain-adapted large language model that recommends real-time drafting decisions in Magic: The Gathering. Starting from an open-weight LLM, we use Low-Rank Adaptation fine-tuning on a dataset of annotated draft logs. With this, we leverage the language modeling capabilities of LLM, and can quickly adapt to different expansions of the game. We benchmark UrzaGPT in comparison to zero-shot LLMs and the state-of-the-art domain-specific model. Untuned, small LLMs like Llama-3-8B are completely unable to draft, but the larger GPT-4o achieves a zero-shot performance of 43%. Using UrzaGPT to fine-tune smaller models, we achieve an accuracy of 66.2% using only 10,000 steps. Despite this not reaching the capability of domain-specific models, we show that solely using LLMs to draft is possible and conclude that using LLMs can enable performant, general, and update-friendly drafting AIs in the future.

Artificial intelligence can now gauge human emotions, and it's being used in everything from education to marketing, experts say. Your emotions could potentially be tracked using your Wi-Fi router and analyzed by AI, according to a new study from London's Queen Mary University. Researchers used radio waves like those used in Wi-Fi to measure heart and breathing rate signals, which could determine how a person is feeling. The study shows just how pervasive emotion-monitoring could become. "In education, AI could be used in adapting content to serve the needs of each child best," Kamilė Jokubaitė, CEO and founder of Attention Insight, who was not involved in the study, said in an email interview.

MRS is a knowledge representation systmt intended for use by Al researchers in building expert systems. It offers a diverse repertory of commands for asserting and retrieving information, with various representatiuns (e.g. The initial system includes a vocabulary of concepts and facts about logic, sets, mappings, arithmetic, and procedures. What differentiates MRS from many other knowledge representation systems is its ability to observe, reason about, and control its own activity. In MRS the system is treated as a domain in its own right.