Asynchronous Gibbs sampling has been recently shown to be fast-mixing and an accurate method for estimating probabilities of events on a small number of variables of a graphical model satisfying Dobrushin's condition~\cite{DeSaOR16}. We investigate whether it can be used to accurately estimate expectations of functions of {\em all the variables} of the model. Under the same condition, we show that the synchronous (sequential) and asynchronous Gibbs samplers can be coupled so that the expected Hamming distance between their (multivariate) samples remains bounded by $O(\tau \log n),$ where $n$ is the number of variables in the graphical model, and $\tau$ is a measure of the asynchronicity. A similar bound holds for any constant power of the Hamming distance. Hence, the expectation of any function that is Lipschitz with respect to a power of the Hamming distance, can be estimated with a bias that grows logarithmically in $n$. Going beyond Lipschitz functions, we consider the bias arising from asynchronicity in estimating the expectation of polynomial functions of all variables in the model.

Asynchronous Gibbs sampling has been recently shown to be fast-mixing and an accurate method for estimating probabilities of events on a small number of variables of a graphical model satisfying Dobrushin's condition~\cite{DeSaOR16}. We investigate whether it can be used to accurately estimate expectations of functions of {\em all the variables} of the model. Under the same condition, we show that the synchronous (sequential) and asynchronous Gibbs samplers can be coupled so that the expected Hamming distance between their (multivariate) samples remains bounded by $O(\tau \log n),$ where $n$ is the number of variables in the graphical model, and $\tau$ is a measure of the asynchronicity. A similar bound holds for any constant power of the Hamming distance. Hence, the expectation of any function that is Lipschitz with respect to a power of the Hamming distance, can be estimated with a bias that grows logarithmically in $n$. Going beyond Lipschitz functions, we consider the bias arising from asynchronicity in estimating the expectation of polynomial functions of all variables in the model.

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Integrating multi-modal clinical data, such as electronic health records (EHR) and chest X-ray images (CXR), is particularly beneficial for clinical prediction tasks. However, in a temporal setting, multi-modal data are often inherently asynchronous. EHR can be continuously collected but CXR is generally taken with a much longer interval due to its high cost and radiation dose. When clinical prediction is needed, the last available CXR image might have been outdated, leading to suboptimal predictions. To address this challenge, we propose DDL-CXR, a method that dynamically generates an up-to-date latent representation of the individualized CXR images.

Heterogeneous scientific workflows consist of numerous types of tasks that require executing on heterogeneous resources. Asynchronous execution of those tasks is crucial to improve resource utilization, task throughput and reduce workflows' makespan. Therefore, middleware capable of scheduling and executing different task types across heterogeneous resources must enable asynchronous execution of tasks. In this paper, we investigate the requirements and properties of the asynchronous task execution of machine learning (ML)-driven high performance computing (HPC) workflows. We model the degree of asynchronicity permitted for arbitrary workflows and propose key metrics that can be used to determine qualitative benefits when employing asynchronous execution. Our experiments represent relevant scientific drivers, we perform them at scale on Summit, and we show that the performance enhancements due to asynchronous execution are consistent with our model.

Asynchronous Gibbs sampling has been recently shown to be fast-mixing and an accurate method for estimating probabilities of events on a small number of variables of a graphical model satisfying Dobrushin's condition \cite{DeSaOR16}. We investigate whether it can be used to accurately estimate expectations of functions of {\em all the variables} of the model. Under the same condition, we show that the synchronous (sequential) and asynchronous Gibbs samplers can be coupled so that the expected Hamming distance between their (multivariate) samples remains bounded by $O(\tau \log n),$ where $n$ is the number of variables in the graphical model, and $\tau$ is a measure of the asynchronicity. A similar bound holds for any constant power of the Hamming distance. Hence, the expectation of any function that is Lipschitz with respect to a power of the Hamming distance, can be estimated with a bias that grows logarithmically in $n$.

Asynchronous Gibbs sampling has been recently shown to be fast-mixing and an accurate method for estimating probabilities of events on a small number of variables of a graphical model satisfying Dobrushin's condition [DSOR16]. We investigate whether it can be used to accurately estimate expectations of functions of all the variables of the model. Under the same condition, we show that the synchronous (sequential) and asynchronous Gibbs samplers can be coupled so that the expected Hamming distance between their (multivariate) samples remains bounded by O(τ log n), where n is the number of variables in the graphical model, and τ is a measure of the asynchronicity. A similar bound holds for any constant power of the Hamming distance. Hence, the expectation of any function that is Lipschitz with respect to a power of the Hamming distance, can be estimated with a bias that grows logarithmically in n. Going beyond Lipschitz functions, we consider the bias arising from asynchronicity in estimating the expectation of polynomial functions of all variables in the model. Using recent concentration of measure results [DDK17, GLP17, GSS18], we show that the bias introduced by the asynchronicity is of smaller order than the standard deviation of the function value already present in the true model. We perform experiments on a multiprocessor machine to empirically illustrate our theoretical findings.

Asynchronous Gibbs sampling has been recently shown to be fast-mixing and an accurate method for estimating probabilities of events on a small number of variables of a graphical model satisfying Dobrushin's condition [DSOR16]. We investigate whether it can be used to accurately estimate expectations of functions of all the variables of the model. Under the same condition, we show that the synchronous (sequential) and asynchronous Gibbs samplers can be coupled so that the expected Hamming distance between their (multivariate) samples remains bounded by O(τ log n), where n is the number of variables in the graphical model, and τ is a measure of the asynchronicity. A similar bound holds for any constant power of the Hamming distance. Hence, the expectation of any function that is Lipschitz with respect to a power of the Hamming distance, can be estimated with a bias that grows logarithmically in n. Going beyond Lipschitz functions, we consider the bias arising from asynchronicity in estimating the expectation of polynomial functions of all variables in the model. Using recent concentration of measure results [DDK17, GLP17, GSS18], we show that the bias introduced by the asynchronicity is of smaller order than the standard deviation of the function value already present in the true model. We perform experiments on a multiprocessor machineto empirically illustrate our theoretical findings.