This paper introduces ArGen (Auto-Regulation of Generative AI systems), a framework for aligning Large Language Models (LLMs) with complex sets of configurable, machine-readable rules spanning ethical principles, operational safety protocols, and regulatory compliance standards. Moving beyond just preference-based alignment, ArGen is designed to ensure LLMs adhere to these multifaceted policies through a novel synthesis of principle-based automated reward scoring, Group Relative Policy Optimisation (GRPO), and an Open Policy Agent (OPA) inspired governance layer. This approach provides the technical foundation for achieving and demonstrating compliance with diverse and nuanced governance requirements. To showcase the framework's capability to operationalize a deeply nuanced and culturally-specific value system, we present an in-depth case study: the development of a medical AI assistant guided by principles from Dharmic ethics (such as Ahimsa and Dharma), as derived from texts like the Bhagavad Gita. This challenging application demonstrates ArGen's adaptability, achieving a 70.9% improvement in domain-scope adherence over the baseline. Through our open-source repository, we show that ArGen's methodology offers a path to 'Governable Al' systems that are technically proficient, ethically robust, and verifiably compliant for safe deployment in diverse global contexts.

We introduce the arbitrary rectangle-range generalized elastic net penalty method, abbreviated to ARGEN, for performing constrained variable selection and regularization in high-dimensional sparse linear models. As a natural extension of the nonnegative elastic net penalty method, ARGEN is proved to have variable selection consistency and estimation consistency under some conditions. The asymptotic behavior in distribution of the ARGEN estimators have been studied. We also propose an algorithm called MU-QP-RR-W-$l_1$ to efficiently solve ARGEN. By conducting simulation study we show that ARGEN outperforms the elastic net in a number of settings. Finally an application of S&P 500 index tracking with constraints on the stock allocations is performed to provide general guidance for adapting ARGEN to solve real-world problems.