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TRACE: Intra-visit Clinical Event Nowcasting via Effective Patient Trajectory Encoding

arXiv.org Artificial Intelligence

Electronic Health Records (EHR) have become a valuable resource for a wide range of predictive tasks in healthcare. However, existing approaches have largely focused on inter-visit event predictions, overlooking the importance of intra-visit nowcasting, which provides prompt clinical insights during an ongoing patient visit. To address this gap, we introduce the task of laboratory measurement prediction within a hospital visit. We study the laboratory data that, however, remained underexplored in previous work. We propose TRACE, a Transformer-based model designed for clinical event nowcasting by encoding patient trajectories. TRACE effectively handles long sequences and captures temporal dependencies through a novel timestamp embedding that integrates decay properties and periodic patterns of data. Additionally, we introduce a smoothed mask for denoising, improving the robustness of the model. Experiments on two large-scale electronic health record datasets demonstrate that the proposed model significantly outperforms previous methods, highlighting its potential for improving patient care through more accurate laboratory measurement nowcasting. The code is available at https://github.com/Amehi/TRACE.


Efficient Inference for Large Reasoning Models: A Survey

arXiv.org Artificial Intelligence

Large Reasoning Models (LRMs) significantly improve the reasoning ability of Large Language Models (LLMs) by learning to reason, exhibiting promising performance in complex task-solving. However, their deliberative reasoning process leads to inefficiencies in token usage, memory consumption, and inference time. Thus, this survey provides a review of efficient inference methods designed specifically for LRMs, focusing on mitigating token inefficiency while preserving the reasoning quality. First, we introduce a taxonomy to group the recent methods into two main categories: (a) explicit compact Chain-of-Thought (CoT), which reduces tokens while keeping the explicit reasoning structure, and (b) implicit latent CoT, which encodes reasoning steps within hidden representations instead of explicit tokens. Meanwhile, we discuss their strengths and weaknesses. Then, we conduct empirical analyses on existing methods from performance and efficiency aspects. Besides, we present open challenges in this field, including human-centric controllable reasoning, trade-off between interpretability and efficiency of reasoning, ensuring safety of efficient reasoning, and broader applications of efficient reasoning. In addition, we highlight key insights for enhancing LRMs' inference efficiency via techniques such as model merging, new architectures, and agent routers. We hope this work serves as a valuable guide, helping researchers overcome challenges in this vibrant field\footnote{https://github.com/yueliu1999/Awesome-Efficient-Inference-for-LRMs}.


MixFunn: A Neural Network for Differential Equations with Improved Generalization and Interpretability

arXiv.org Artificial Intelligence

We introduce MixFunn, a novel neural network architecture designed to solve differential equations with enhanced precision, interpretability, and generalization capability. The architecture comprises two key components: the mixed-function neuron, which integrates multiple parameterized nonlinear functions to improve representational flexibility, and the second-order neuron, which combines a linear transformation of its inputs with a quadratic term to capture cross-combinations of input variables. These features significantly enhance the expressive power of the network, enabling it to achieve comparable or superior results with drastically fewer parameters and a reduction of up to four orders of magnitude compared to conventional approaches. We applied MixFunn in a physics-informed setting to solve differential equations in classical mechanics, quantum mechanics, and fluid dynamics, demonstrating its effectiveness in achieving higher accuracy and improved generalization to regions outside the training domain relative to standard machine learning models. Furthermore, the architecture facilitates the extraction of interpretable analytical expressions, offering valuable insights into the underlying solutions.


Evaluating LLM-based Agents for Multi-Turn Conversations: A Survey

arXiv.org Artificial Intelligence

This survey examines evaluation methods for large language model (LLM)-based agents in multi-turn conversational settings. Using a PRISMA-inspired framework, we systematically reviewed nearly 250 scholarly sources, capturing the state of the art from various venues of publication, and establishing a solid foundation for our analysis. Our study offers a structured approach by developing two interrelated taxonomy systems: one that defines \emph{what to evaluate} and another that explains \emph{how to evaluate}. The first taxonomy identifies key components of LLM-based agents for multi-turn conversations and their evaluation dimensions, including task completion, response quality, user experience, memory and context retention, as well as planning and tool integration. These components ensure that the performance of conversational agents is assessed in a holistic and meaningful manner. The second taxonomy system focuses on the evaluation methodologies. It categorizes approaches into annotation-based evaluations, automated metrics, hybrid strategies that combine human assessments with quantitative measures, and self-judging methods utilizing LLMs. This framework not only captures traditional metrics derived from language understanding, such as BLEU and ROUGE scores, but also incorporates advanced techniques that reflect the dynamic, interactive nature of multi-turn dialogues.


Endo-TTAP: Robust Endoscopic Tissue Tracking via Multi-Facet Guided Attention and Hybrid Flow-point Supervision

arXiv.org Artificial Intelligence

Accurate tissue point tracking in endoscopic videos is critical for robotic-assisted surgical navigation and scene understanding, but remains challenging due to complex deformations, instrument occlusion, and the scarcity of dense trajectory annotations. Existing methods struggle with long-term tracking under these conditions due to limited feature utilization and annotation dependence. We present Endo-TTAP, a novel framework addressing these challenges through: (1) A Multi-Facet Guided Attention (MFGA) module that synergizes multi-scale flow dynamics, DINOv2 semantic embeddings, and explicit motion patterns to jointly predict point positions with uncertainty and occlusion awareness; (2) A two-stage curriculum learning strategy employing an Auxiliary Curriculum Adapter (ACA) for progressive initialization and hybrid supervision. Stage I utilizes synthetic data with optical flow ground truth for uncertainty-occlusion regularization, while Stage II combines unsupervised flow consistency and semi-supervised learning with refined pseudo-labels from off-the-shelf trackers. Extensive validation on two MICCAI Challenge datasets and our collected dataset demonstrates that Endo-TTAP achieves state-of-the-art performance in tissue point tracking, particularly in scenarios characterized by complex endoscopic conditions. The source code and dataset will be available at https://anonymous.4open.science/r/Endo-TTAP-36E5.


Challenges and Paths Towards AI for Software Engineering

arXiv.org Artificial Intelligence

AI for software engineering has made remarkable progress recently, becoming a notable success within generative AI. Despite this, there are still many challenges that need to be addressed before automated software engineering reaches its full potential. It should be possible to reach high levels of automation where humans can focus on the critical decisions of what to build and how to balance difficult tradeoffs while most routine development effort is automated away. Reaching this level of automation will require substantial research and engineering efforts across academia and industry. In this paper, we aim to discuss progress towards this in a threefold manner. First, we provide a structured taxonomy of concrete tasks in AI for software engineering, emphasizing the many other tasks in software engineering beyond code generation and completion. Second, we outline several key bottlenecks that limit current approaches. Finally, we provide an opinionated list of promising research directions toward making progress on these bottlenecks, hoping to inspire future research in this rapidly maturing field.


Neuroplasticity in Artificial Intelligence -- An Overview and Inspirations on Drop In & Out Learning

arXiv.org Artificial Intelligence

Artificial Intelligence (AI) has achieved new levels of performance and spread in public usage with the rise of deep neural networks (DNNs). Initially inspired by human neurons and their connections, NNs have become the foundation of AI models for many advanced architectures. However, some of the most integral processes in the human brain, particularly neurogenesis and neuroplasticity in addition to the more spread neuroapoptosis have largely been ignored in DNN architecture design. Instead, contemporary AI development predominantly focuses on constructing advanced frameworks, such as large language models, which retain a static structure of neural connections during training and inference. In this light, we explore how neurogenesis, neuroapoptosis, and neuroplasticity can inspire future AI advances. Specifically, we examine analogous activities in artificial NNs, introducing the concepts of ``dropin'' for neurogenesis and revisiting ``dropout'' and structural pruning for neuroapoptosis. We additionally suggest neuroplasticity combining the two for future large NNs in ``life-long learning'' settings following the biological inspiration. We conclude by advocating for greater research efforts in this interdisciplinary domain and identifying promising directions for future exploration.


A Brief Review of The Shapley Value

Neural Information Processing Systems

Given a value function v, the Shapley value is a solution to distributing the payoff v(N) to parties in N [14]. Given an order of parties (i.e., a permutation ฯ€ of N), party i joins the coalition P The Shapley value is'fair' since it is the unique solution that satisfies several desirable properties as elaborated below. It ensures that all of v(N) are distributed to the parties. It implies parties with equal marginal contributions to any coalitions have the same payoff. A reward allocation scheme is replication-robust if a party cannot increase its rewards by replicating its data and participating in the collaboration as multiple parties.



Unitary convolutions for learning on graphs and groups

Neural Information Processing Systems

In recent years, the design of specialized machine learning architectures for structured data has received a surge of interest. Of particular interest are architectures for data domains with inherent symmetries, such as permutation-invariance in graphs and sets, translation-invariance in images, and other symmetries that arise from fundamental laws of physics in scientific data.