Objective: Accurate visual classification of bladder tissue during Trans-Urethral Resection of Bladder Tumor (TURBT) procedures is essential to improve early cancer diagnosis and treatment. During TURBT interventions, White Light Imaging (WLI) and Narrow Band Imaging (NBI) techniques are used for lesion detection. Each imaging technique provides diverse visual information that allows clinicians to identify and classify cancerous lesions. Computer vision methods that use both imaging techniques could improve endoscopic diagnosis. We address the challenge of tissue classification when annotations are available only in one domain, in our case WLI, and the endoscopic images correspond to an unpaired dataset, i.e. there is no exact equivalent for every image in both NBI and WLI domains. Method: We propose a semi-surprised Generative Adversarial Network (GAN)-based method composed of three main components: a teacher network trained on the labeled WLI data; a cycle-consistency GAN to perform unpaired image-to-image translation, and a multi-input student network. To ensure the quality of the synthetic images generated by the proposed GAN we perform a detailed quantitative, and qualitative analysis with the help of specialists. Conclusion: The overall average classification accuracy, precision, and recall obtained with the proposed method for tissue classification are 0.90, 0.88, and 0.89 respectively, while the same metrics obtained in the unlabeled domain (NBI) are 0.92, 0.64, and 0.94 respectively. The quality of the generated images is reliable enough to deceive specialists. Significance: This study shows the potential of using semi-supervised GAN-based bladder tissue classification when annotations are limited in multi-domain data. The dataset is available at https://zenodo.org/record/7741476#.ZBQUK7TMJ6k

This paper builds on our previous work by exploiting Artificial Intelligence to predict individual grip force variability in manual robot control. Grip forces were recorded from various loci in the dominant and non dominant hands of individuals by means of wearable wireless sensor technology. Statistical analyses bring to the fore skill specific temporal variations in thousands of grip forces of a complete novice and a highly proficient expert in manual robot control. A brain inspired neural network model that uses the output metric of a Self Organizing Map with unsupervised winner take all learning was run on the sensor output from both hands of each user. The neural network metric expresses the difference between an input representation and its model representation at any given moment in time t and reliably captures the differences between novice and expert performance in terms of grip force variability.Functionally motivated spatiotemporal analysis of individual average grip forces, computed for time windows of constant size in the output of a restricted amount of task-relevant sensors in the dominant (preferred) hand, reveal finger-specific synergies reflecting robotic task skill. The analyses lead the way towards grip force monitoring in real time to permit tracking task skill evolution in trainees, or identify individual proficiency levels in human robot interaction in environmental contexts of high sensory uncertainty. Parsimonious Artificial Intelligence (AI) assistance will contribute to the outcome of new types of surgery, in particular single-port approaches such as NOTES (Natural Orifice Transluminal Endoscopic Surgery) and SILS (Single Incision Laparoscopic Surgery).