Recent research applying text-to-image (T2I) diffusion models to real-world super-resolution (SR) has achieved remarkable success. However, fundamental misalignments between T2I and SR targets result in a dilemma between inference speed and detail fidelity. Specifically, T2I tasks prioritize multi-step inversion to synthesize coherent outputs aligned with textual prompts and shrink the latent space to reduce generating complexity. Contrariwise, SR tasks preserve most information from low-resolution input while solely restoring high-frequency details, thus necessitating sufficient latent space and fewer inference steps. To bridge the gap, we present a one-step diffusion model for generative detail restoration, GenDR, distilled from a tailored diffusion model with larger latent space. In detail, we train a new SD2.1-VAE16 (0.9B) via representation alignment to expand latent space without enlarging the model size. Regarding step-distillation, we propose consistent score identity distillation (CiD) that incorporates SR task-specific loss into score distillation to leverage more SR priors and align the training target. Furthermore, we extend CiD with adversarial learning and representation alignment (CiDA) to enhance perceptual quality and accelerate training. We also polish the pipeline to achieve a more efficient inference. Experimental results demonstrate that GenDR achieves state-of-the-art performance in both quantitative metrics and visual fidelity.

Humanoid robots are designed to perform diverse loco-manipulation tasks. However, they face challenges due to their high-dimensional and unstable dynamics, as well as the complex contact-rich nature of the tasks. Model-based optimal control methods offer precise and systematic control but are limited by high computational complexity and accurate contact sensing. On the other hand, reinforcement learning (RL) provides robustness and handles high-dimensional spaces but suffers from inefficient learning, unnatural motion, and sim-to-real gaps. To address these challenges, we introduce Opt2Skill, an end-to-end pipeline that combines model-based trajectory optimization with RL to achieve robust whole-body loco-manipulation. We generate reference motions for the Digit humanoid robot using differential dynamic programming (DDP) and train RL policies to track these trajectories. Our results demonstrate that Opt2Skill outperforms pure RL methods in both training efficiency and task performance, with optimal trajectories that account for torque limits enhancing trajectory tracking. We successfully transfer our approach to real-world applications.

Medical images and radiology reports are crucial for diagnosing medical conditions, highlighting the importance of quantitative analysis for clinical decision-making. However, the diversity and cross-source heterogeneity of these data challenge the generalizability of current data-mining methods. Multimodal large language models (MLLMs) have recently transformed many domains, significantly affecting the medical field. Notably, Gemini-Vision-series (Gemini) and GPT-4-series (GPT-4) models have epitomized a paradigm shift in Artificial General Intelligence (AGI) for computer vision, showcasing their potential in the biomedical domain. In this study, we evaluated the performance of the Gemini, GPT-4, and 4 popular large models for an exhaustive evaluation across 14 medical imaging datasets, including 5 medical imaging categories (dermatology, radiology, dentistry, ophthalmology, and endoscopy), and 3 radiology report datasets. The investigated tasks encompass disease classification, lesion segmentation, anatomical localization, disease diagnosis, report generation, and lesion detection. Our experimental results demonstrated that Gemini-series models excelled in report generation and lesion detection but faces challenges in disease classification and anatomical localization. Conversely, GPT-series models exhibited proficiency in lesion segmentation and anatomical localization but encountered difficulties in disease diagnosis and lesion detection. Additionally, both the Gemini series and GPT series contain models that have demonstrated commendable generation efficiency. While both models hold promise in reducing physician workload, alleviating pressure on limited healthcare resources, and fostering collaboration between clinical practitioners and artificial intelligence technologies, substantial enhancements and comprehensive validations remain imperative before clinical deployment.

Adaptive video streaming requires efficient bitrate ladder construction to meet heterogeneous network conditions and end-user demands. Per-title optimized encoding typically traverses numerous encoding parameters to search the Pareto-optimal operating points for each video. Recently, researchers have attempted to predict the content-optimized bitrate ladder for pre-encoding overhead reduction. However, existing methods commonly estimate the encoding parameters on the Pareto front and still require subsequent pre-encodings. In this paper, we propose to directly predict the optimal transcoding resolution at each preset bitrate for efficient bitrate ladder construction. We adopt a Temporal Attentive Gated Recurrent Network to capture spatial-temporal features and predict transcoding resolutions as a multi-task classification problem. We demonstrate that content-optimized bitrate ladders can thus be efficiently determined without any pre-encoding. Our method well approximates the ground-truth bitrate-resolution pairs with a slight Bj{\o}ntegaard Delta rate loss of 1.21% and significantly outperforms the state-of-the-art fixed ladder.

In this article, the state estimation problems with unknown process noise and measurement noise covariances for both linear and nonlinear systems are considered. By formulating the joint estimation of system state and noise parameters into an optimization problem, a novel adaptive Kalman filter method based on conjugate-computation variational inference, referred to as CVIAKF, is proposed to approximate the joint posterior probability density function of the latent variables. Unlike the existing adaptive Kalman filter methods utilizing variational inference in natural-parameter space, CVIAKF performs optimization in expectation-parameter space, resulting in a faster and simpler solution. Meanwhile, CVIAKF divides optimization objectives into conjugate and non-conjugate parts of nonlinear dynamical models, whereas conjugate computations and stochastic mirror-descent are applied, respectively. Remarkably, the reparameterization trick is used to reduce the variance of stochastic gradients of the non-conjugate parts. The effectiveness of CVIAKF is validated through synthetic and real-world datasets of maneuvering target tracking.

In this paper, we present a large-scale evaluation probing GPT-4V's capabilities and limitations for biomedical image analysis. GPT-4V represents a breakthrough in artificial general intelligence (AGI) for computer vision, with applications in the biomedical domain. We assess GPT-4V's performance across 16 medical imaging categories, including radiology, oncology, ophthalmology, pathology, and more. Tasks include modality recognition, anatomy localization, disease diagnosis, report generation, and lesion detection. The extensive experiments provide insights into GPT-4V's strengths and weaknesses. Results show GPT-4V's proficiency in modality and anatomy recognition but difficulty with disease diagnosis and localization. GPT-4V excels at diagnostic report generation, indicating strong image captioning skills. While promising for biomedical imaging AI, GPT-4V requires further enhancement and validation before clinical deployment. We emphasize responsible development and testing for trustworthy integration of biomedical AGI. This rigorous evaluation of GPT-4V on diverse medical images advances understanding of multimodal large language models (LLMs) and guides future work toward impactful healthcare applications.

Radiology report generation, as a key step in medical image analysis, is critical to the quantitative analysis of clinically informed decision-making levels. However, complex and diverse radiology reports with cross-source heterogeneity pose a huge generalizability challenge to the current methods under massive data volume, mainly because the style and normativity of radiology reports are obviously distinctive among institutions, body regions inspected and radiologists. Recently, the advent of large language models (LLM) offers great potential for recognizing signs of health conditions. To resolve the above problem, we collaborate with the Second Xiangya Hospital in China and propose ChatRadio-Valuer based on the LLM, a tailored model for automatic radiology report generation that learns generalizable representations and provides a basis pattern for model adaptation in sophisticated analysts' cases. Specifically, ChatRadio-Valuer is trained based on the radiology reports from a single institution by means of supervised fine-tuning, and then adapted to disease diagnosis tasks for human multi-system evaluation (i.e., chest, abdomen, muscle-skeleton, head, and maxillofacial $\&$ neck) from six different institutions in clinical-level events. The clinical dataset utilized in this study encompasses a remarkable total of \textbf{332,673} observations. From the comprehensive results on engineering indicators, clinical efficacy and deployment cost metrics, it can be shown that ChatRadio-Valuer consistently outperforms state-of-the-art models, especially ChatGPT (GPT-3.5-Turbo) and GPT-4 et al., in terms of the diseases diagnosis from radiology reports. ChatRadio-Valuer provides an effective avenue to boost model generalization performance and alleviate the annotation workload of experts to enable the promotion of clinical AI applications in radiology reports.

The rise of large language models (LLMs) has marked a pivotal shift in the field of natural language processing (NLP). LLMs have revolutionized a multitude of domains, and they have made a significant impact in the medical field. Large language models are now more abundant than ever, and many of these models exhibit bilingual capabilities, proficient in both English and Chinese. However, a comprehensive evaluation of these models remains to be conducted. This lack of assessment is especially apparent within the context of radiology NLP. This study seeks to bridge this gap by critically evaluating thirty two LLMs in interpreting radiology reports, a crucial component of radiology NLP. Specifically, the ability to derive impressions from radiologic findings is assessed. The outcomes of this evaluation provide key insights into the performance, strengths, and weaknesses of these LLMs, informing their practical applications within the medical domain.