Artificial Intelligence (AI) has become a transformative tool in scientific research, driving breakthroughs across numerous disciplines [5-11]. Despite these achievements, neural networks, which form the backbone of many AI systems, exhibit significant vulnerabilities. One of the most concerning issues is their susceptibility to adversarial attacks [1, 2, 12, 13]. These attacks involve making small, often imperceptible changes to the input data, causing AI systems to make incorrect predictions (Figure 1), highlighting a critical weakness: AI systems can fail under minimal perturbations - a phenomenon completely unseen in classical methods. The impact of adversarial attacks has been extensively studied in the context of image classification [14-16].

Document-level relation extraction aims to discover relations between entities across a whole document. How to build the dependency of entities from different sentences in a document remains to be a great challenge. Current approaches either leverage syntactic trees to construct document-level graphs or aggregate inference information from different sentences. In this paper, we build cross-sentence dependencies by inferring compositional relations between inter-sentence mentions. Adopting aggressive linking strategy, intermediate relations are reasoned on the document-level graphs by mention convolution. We further notice the generalization problem of NA instances, which is caused by incomplete annotation and worsened by fully-connected mention pairs. An improved ranking loss is proposed to attend this problem. Experiments show the connections between different mentions are crucial to document-level relation extraction, which enables the model to extract more meaningful higher-level compositional relations.