Graph Neural Networks (GNNs) have recently gained widespread attention as a successful tool for analyzing graph-structured data. However, imperfect graph structure with noisy links lacks enough robustness and may damage graph representations, therefore limiting the GNNs' performance in practical tasks. Moreover, existing generative architectures fail to fit discriminative graph-related tasks. To tackle these issues, we introduce an unsupervised method based on a joint of generative training and discriminative training to learn graph structure and representation, aiming to improve the discriminative performance of generative models. We propose an Energy-based Contrastive Learning (ECL) guided Graph Structure Refinement (GSR) framework, denoted as ECL-GSR. To our knowledge, this is the first work to combine energy-based models with contrastive learning for GSR. Specifically, we leverage ECL to approximate the joint distribution of sample pairs, which increases the similarity between representations of positive pairs while reducing the similarity between negative ones. Refined structure is produced by augmenting and removing edges according to the similarity metrics among node representations. Extensive experiments demonstrate that ECL-GSR outperforms the state-of-the-art on eight benchmark datasets in node classification. ECL-GSR achieves faster training with fewer samples and memories against the leading baseline, highlighting its simplicity and efficiency in downstream tasks.

Large-scale pre-trained Vision-Language Models (VLMs) have gained prominence in various visual and multimodal tasks, yet the deployment of VLMs on downstream application platforms remains challenging due to their prohibitive requirements of training samples and computing resources. Fine-tuning and quantization of VLMs can substantially reduce the sample and computation costs, which are in urgent need. There are two prevailing paradigms in quantization, Quantization-Aware Training (QAT) can effectively quantize large-scale VLMs but incur a huge training cost, while low-bit Post-Training Quantization (PTQ) suffers from a notable performance drop. We propose a method that balances fine-tuning and quantization named ``Prompt for Quantization'' (P4Q), in which we design a lightweight architecture to leverage contrastive loss supervision to enhance the recognition performance of a PTQ model. Our method can effectively reduce the gap between image features and text features caused by low-bit quantization, based on learnable prompts to reorganize textual representations and a low-bit adapter to realign the distributions of image and text features. We also introduce a distillation loss based on cosine similarity predictions to distill the quantized model using a full-precision teacher. Extensive experimental results demonstrate that our P4Q method outperforms prior arts, even achieving comparable results to its full-precision counterparts. For instance, our 8-bit P4Q can theoretically compress the CLIP-ViT/B-32 by 4 $\times$ while achieving 66.94\% Top-1 accuracy, outperforming the learnable prompt fine-tuned full-precision model by 2.24\% with negligible additional parameters on the ImageNet dataset.

Sharpness-Aware Minimization (SAM) enhances generalization by reducing a Max-Sharpness (MaxS). Despite the practical success, we empirically found that the MAxS behind SAM's generalization enhancements face the "Flatness Indicator Problem" (FIP), where SAM only considers the flatness in the direction of gradient ascent, resulting in a next minimization region that is not sufficiently flat. A better Flatness Indicator (FI) would bring a better generalization of neural networks. Because SAM is a greedy search method in nature. In this paper, we propose to utilize the difference between the training loss and the minimum loss over the neighborhood surrounding the current weight, which we denote as Min-Sharpness (MinS). By merging MaxS and MinS, we created a better FI that indicates a flatter direction during the optimization. Specially, we combine this FI with SAM into the proposed Bilateral SAM (BSAM) which finds a more flatter minimum than that of SAM. The theoretical analysis proves that BSAM converges to local minima. Extensive experiments demonstrate that BSAM offers superior generalization performance and robustness compared to vanilla SAM across various tasks, i.e., classification, transfer learning, human pose estimation, and network quantization. Code is publicly available at: https://github.com/ajiaaa/BSAM.

Sharpness-Aware Minimization (SAM) has emerged as a promising approach for effectively reducing the generalization error. However, SAM incurs twice the computational cost compared to base optimizer (e.g., SGD). We propose Asymptotic Unbiased Sampling with respect to iterations to accelerate SAM (AUSAM), which maintains the model's generalization capacity while significantly enhancing computational efficiency. Concretely, we probabilistically sample a subset of data points beneficial for SAM optimization based on a theoretically guaranteed criterion, i.e., the Gradient Norm of each Sample (GNS). We further approximate the GNS by the difference in loss values before and after perturbation in SAM. As a plug-and-play, architecture-agnostic method, our approach consistently accelerates SAM across a range of tasks and networks, i.e., classification, human pose estimation and network quantization. On CIFAR10/100 and Tiny-ImageNet, AUSAM achieves results comparable to SAM while providing a speedup of over 70%. Compared to recent dynamic data pruning methods, AUSAM is better suited for SAM and excels in maintaining performance. Additionally, AUSAM accelerates optimization in human pose estimation and model quantization without sacrificing performance, demonstrating its broad practicality.

The widespread outbreak of the COVID-19 pandemic has sounded a warning about the globalization challenges in public health. In this context, the establishment of large-scale public health datasets, of medical models, and of decision-making systems with a human-centric approach holds strategic significance. Recently, groundbreaking advancements have emerged in AI methods for physiological signal monitoring and disease diagnosis based on camera sensors. These approaches, requiring no specialized medical equipment, offer convenient manners of collecting large-scale medical data in response to public health events. Not only do these methods facilitate the acquisition of unbiased datasets, but also enable the development of fair large medical models (LMMs). Therefore, we outline a prospective framework and heuristic vision for a public health large medical model (PHLMM) utilizing visual-based physiological monitoring (VBPM) technology. The PHLMM can be considered as a "convenient and universal" framework for public health, advancing the United Nations' "Sustainable Development Goals 2030", particularly in its promotion of Universal Health Coverage (UHC) in low- and middle-income countries. Furthermore, this paper provides an outlook on the crucial application prospects of PHLMM in response to public health challenges and its significant role in the field of AI for medicine (AI4medicine). In summary, PHLMM serves as a solution for constructing a large-scale medical database and LMM, eliminating the issue of dataset bias and unfairness in AI models. The outcomes will contribute to the establishment of an LMM framework for public health, acting as a crucial bridge for advancing AI4medicine.

Cross-modality fusing complementary information from different modalities effectively improves object detection performance, making it more useful and robust for a wider range of applications. Existing fusion strategies combine different types of images or merge different backbone features through elaborated neural network modules. However, these methods neglect that modality disparities affect cross-modality fusion performance, as different modalities with different camera focal lengths, placements, and angles are hardly fused. In this paper, we investigate cross-modality fusion by associating cross-modal features in a hidden state space based on an improved Mamba with a gating mechanism. We design a Fusion-Mamba block (FMB) to map cross-modal features into a hidden state space for interaction, thereby reducing disparities between cross-modal features and enhancing the representation consistency of fused features. FMB contains two modules: the State Space Channel Swapping (SSCS) module facilitates shallow feature fusion, and the Dual State Space Fusion (DSSF) enables deep fusion in a hidden state space. Through extensive experiments on public datasets, our proposed approach outperforms the state-of-the-art methods on $m$AP with 5.9% on $M^3FD$ and 4.9% on FLIR-Aligned datasets, demonstrating superior object detection performance. To the best of our knowledge, this is the first work to explore the potential of Mamba for cross-modal fusion and establish a new baseline for cross-modality object detection.

During endovascular interventions, physicians have to perform accurate and immediate operations based on the available real-time information, such as the shape and position of guidewires observed on the fluoroscopic images, haptic information and the patients' physiological signals. For this purpose, real-time and accurate guidewire segmentation and tracking can enhance the visualization of guidewires and provide visual feedback for physicians during the intervention as well as for robot-assisted interventions. Nevertheless, this task often comes with the challenge of elongated deformable structures that present themselves with low contrast in the noisy fluoroscopic image sequences. To address these issues, a two-stage deep learning framework for real-time guidewire segmentation and tracking is proposed. In the first stage, a Yolov5s detector is trained, using the original X-ray images as well as synthetic ones, which is employed to output the bounding boxes of possible target guidewires. More importantly, a refinement module based on spatiotemporal constraints is incorporated to robustly localize the guidewire and remove false detections. In the second stage, a novel and efficient network is proposed to segment the guidewire in each detected bounding box. The network contains two major modules, namely a hessian-based enhancement embedding module and a dual self-attention module. Quantitative and qualitative evaluations on clinical intra-operative images demonstrate that the proposed approach significantly outperforms our baselines as well as the current state of the art and, in comparison, shows higher robustness to low quality images.

The remarkable performance of Vision Transformers (ViTs) typically requires an extremely large training cost. Existing methods have attempted to accelerate the training of ViTs, yet typically disregard method universality with accuracy dropping. Meanwhile, they break the training consistency of the original transformers, including the consistency of hyper-parameters, architecture, and strategy, which prevents them from being widely applied to different Transformer networks. In this paper, we propose a novel token growth scheme Token Expansion (termed ToE) to achieve consistent training acceleration for ViTs. We introduce an "initialization-expansion-merging" pipeline to maintain the integrity of the intermediate feature distribution of original transformers, preventing the loss of crucial learnable information in the training process. ToE can not only be seamlessly integrated into the training and fine-tuning process of transformers (e.g., DeiT and LV-ViT), but also effective for efficient training frameworks (e.g., EfficientTrain), without twisting the original training hyper-parameters, architecture, and introducing additional training strategies. Extensive experiments demonstrate that ToE achieves about 1.3x faster for the training of ViTs in a lossless manner, or even with performance gains over the full-token training baselines. Code is available at https://github.com/Osilly/TokenExpansion .

Semi-supervised learning (SSL) is a practical challenge in computer vision. Pseudo-label (PL) methods, e.g., FixMatch and FreeMatch, obtain the State Of The Art (SOTA) performances in SSL. These approaches employ a threshold-to-pseudo-label (T2L) process to generate PLs by truncating the confidence scores of unlabeled data predicted by the self-training method. However, self-trained models typically yield biased and high-variance predictions, especially in the scenarios when a little labeled data are supplied. To address this issue, we propose a lightweight channel-based ensemble method to effectively consolidate multiple inferior PLs into the theoretically guaranteed unbiased and low-variance one. Importantly, our approach can be readily extended to any SSL framework, such as FixMatch or FreeMatch. Experimental results demonstrate that our method significantly outperforms state-of-the-art techniques on CIFAR10/100 in terms of effectiveness and efficiency.

However, SAM requires two forward In recent years, some research has been proposed to understand and backward operations in one iteration, which results in the generalization of DNNs [Keskar et al., 2017; SAM's optimization speed being only half that of SGD. In Zhang et al., 2021; Mulayoff and Michaeli, 2020; Andriushchenko some scenarios, dedicating twice the training time to achieve and Flammarion, 2022; Zhou et al., 2021; only a marginal improvement in accuracy may not strike an Zhou et al., 2022]. Several studies have verified the relationship optimal balance between accuracy and efficiency. For example, between flat minima and generalization error [Dinh et when SAM is employed to optimize WideResNet-28-10 al., 2017; Li et al., 2018; Jiang et al., 2020; Liu et al., 2020; on CIFAR-100, despite achieving a higher test accuracy than Sun et al., 2021]. Among these studies, Jiang et al. [Jiang et SGD (84.45% vs. 82.89%), the optimization speed is only al., 2020] explored over 40 complexity measures and demonstrated half that of SGD (343 imgs/s vs. 661 imgs/s), as illustrated in that a sharpness-based measure exhibits the highest Figure 1.