Biomedical visual question answering (VQA) has been widely studied and has demonstrated significant application value and potential in fields such as assistive medical diagnosis. Despite their success, current biomedical VQA models perform multimodal information interaction only at the model level within large language models (LLMs), leading to suboptimal multimodal semantic alignment when dealing with complex tasks. To address this issue, we propose BioD2C: a novel Dual-level Semantic C onsistency C onstraint Framework for Biomedical VQA, which achieves dual-level semantic interaction alignment at both the model and feature levels, enabling the model to adaptively learn visual features based on the question. Specifically, we firstly integrate textual features into visual features via an image-text fusion mechanism as feature-level semantic interaction, obtaining visual features conditioned on the given text; and then introduce a text-queue-based cross-modal soft semantic loss function to further align the image semantics with the question semantics. Specifically, in this work, we establish a new dataset, BioVGQ, to address inherent biases in prior datasets by filtering manually-altered images and aligning question-answer pairs with multimodal context, and train our model on this dataset. Extensive experimental results demonstrate that BioD2C achieves state-of-the-art (SOTA) performance across multiple downstream datasets, showcasing its robustness, generalizabil-ity, and potential to advance biomedical VQA research. The source code of this work and the BioVGQ dataset can be accessed through code and dataset. Keywords: Biomedical VQA Dual Interaction Semantic Alignment 1 Introduction Biomedical VQA aims to design and develop systems capable of understanding biomedical images and generating relevant answers based on given textual instructions.

Immunohistochemistry (IHC) staining plays a significant role in the evaluation of diseases such as breast cancer. The H&E-to-IHC transformation based on generative models provides a simple and cost-effective method for obtaining IHC images. Although previous models can perform digital coloring well, they still suffer from (i) coloring only through the pixel features that are not prominent in HE, which is easy to cause information loss in the coloring process; (ii) The lack of pixel-perfect H&E-IHC groundtruth pairs poses a challenge to the classical L1 loss.To address the above challenges, we propose an adaptive information enhanced coloring framework based on feature extractors. We first propose the VMFE module to effectively extract the color information features using multi-scale feature extraction and wavelet transform convolution, while combining the shared decoder for feature fusion. The high-performance dual feature extractor of H&E-IHC is trained by contrastive learning, which can effectively perform feature alignment of HE-IHC in high latitude space. At the same time, the trained feature encoder is used to enhance the features and adaptively adjust the loss in the HE section staining process to solve the problems related to unclear and asymmetric information. We have tested on different datasets and achieved excellent performance.Our code is available at https://github.com/babyinsunshine/CEFF

Adapting machine learning models to new domains without labeled data, especially when source data is inaccessible, is a critical challenge in applications like medical imaging, autonomous driving, and remote sensing. This task, known as Source-Free Unsupervised Domain Adaptation (SFUDA), involves adapting a pre-trained model to a target domain using only unlabeled target data, which can lead to issues such as overfitting, underfitting, and poor generalization due to domain discrepancies and noise. Existing SFUDA methods often rely on single-model architectures, struggling with uncertainty and variability in the target domain. To address these challenges, we propose DRIVE (Dual-Robustness through Information Variability and Entropy), a novel SFUDA framework leveraging a dual-model architecture. The two models, initialized with identical weights, work in parallel to capture diverse target domain characteristics. One model is exposed to perturbations via projection gradient descent (PGD) guided by mutual information, focusing on high-uncertainty regions. We also introduce an entropy-aware pseudo-labeling strategy that adjusts label weights based on prediction uncertainty, ensuring the model focuses on reliable data while avoiding noisy regions. The adaptation process has two stages: the first aligns the models on stable features using a mutual information consistency loss, and the second dynamically adjusts the perturbation level based on the loss from the first stage, encouraging the model to explore a broader range of the target domain while preserving existing performance. This enhances generalization capabilities and robustness against interference. Evaluations on standard SFUDA benchmarks show that DRIVE consistently outperforms previous methods, delivering improved adaptation accuracy and stability across complex target domains.

Concept Bottleneck Models (CBMs) enhance model interpretability by introducing human-understandable concepts within the architecture. However, existing CBMs assume static datasets, limiting their ability to adapt to real-world, continuously evolving data streams. To address this, we define a novel concept-incremental and class-incremental continual learning task for CBMs, enabling models to accumulate new concepts and classes over time while retaining previously learned knowledge. To achieve this, we propose CONceptual Continual Incremental Learning (CONCIL), a framework that prevents catastrophic forgetting by reformulating concept and decision layer updates as linear regression problems, thus eliminating the need for gradient-based updates. CONCIL requires only recursive matrix operations, making it computationally efficient and suitable for real-time and large-scale data applications. Experimental results demonstrate that CONCIL achieves "absolute knowledge memory" and outperforms traditional CBM methods in concept- and class-incremental settings, establishing a new benchmark for continual learning in CBMs.

Class-incremental pattern recognition in time series is a significant problem, which aims to learn from continually arriving streaming data examples with incremental classes. A primary challenge in this problem is catastrophic forgetting, where the incorporation of new data samples causes the models to forget previously learned information. While the replay-based methods achieve promising results by storing historical data to address catastrophic forgetting, they come with the invasion of data privacy. On the other hand, the exemplar-free methods preserve privacy but suffer from significantly decreased accuracy. To address these challenges, we proposed TS-ACL, a novel Time Series Analytic Continual Learning framework for privacy-preserving and class-incremental pattern recognition. Identifying gradient descent as the root of catastrophic forgetting, TS-ACL transforms each update of the model into a gradient-free analytical learning process with a closed-form solution. By leveraging a pre-trained frozen encoder for embedding extraction, TS-ACL only needs to recursively update an analytic classifier in a lightweight manner. This way, TS-ACL simultaneously achieves non-forgetting, privacy preservation, and lightweight consumption, making it widely suitable for various applications, particularly in edge computing scenarios. Extensive experiments on five benchmark datasets confirm the superior and robust performance of TS-ACL compared to existing advanced methods. Code is available at https://github.com/asdasdczxczq/TS-ACL.

Large Language Models (LLMs) are powerful tools for text generation, translation, and summarization, but they often suffer from hallucinations-instances where they fail to maintain the fidelity and coherence of contextual information during decoding, sometimes overlooking critical details due to their sampling strategies and inherent biases from training data and fine-tuning discrepancies. These hallucinations can propagate through the web, affecting the trustworthiness of information disseminated online. To address this issue, we propose a novel decoding strategy that leverages absorbing Markov chains to quantify the significance of contextual information and measure the extent of information loss during generation. By considering all possible paths from the first to the last token, our approach enhances the reliability of model outputs without requiring additional training or external data. Evaluations on datasets including TruthfulQA, FACTOR, and HaluEval highlight the superior performance of our method in mitigating hallucinations, underscoring the necessity of ensuring accurate information flow in web-based applications.

Millimeter-wave radar is promising to provide robust and accurate vital sign monitoring in an unobtrusive manner. However, the radar signal might be distorted in propagation by ambient noise or random body movement, ruining the subtle cardiac activities and destroying the vital sign recovery. In particular, the recovery of electrocardiogram (ECG) signal heavily relies on the deep-learning model and is sensitive to noise. Therefore, this work creatively deconstructs the radar-based ECG recovery into three individual tasks and proposes a multi-task learning (MTL) framework, radarODE-MTL, to increase the robustness against consistent and abrupt noises. In addition, to alleviate the potential conflicts in optimizing individual tasks, a novel multi-task optimization strategy, eccentric gradient alignment (EGA), is proposed to dynamically trim the task-specific gradients based on task difficulties in orthogonal space. The proposed radarODE-MTL with EGA is evaluated on the public dataset with prominent improvements in accuracy, and the performance remains consistent under noises. The experimental results indicate that radarODE-MTL could reconstruct accurate ECG signals robustly from radar signals and imply the application prospect in real-life situations. The code is available at: http://github.com/ZYY0844/radarODE-MTL.

In the rapidly evolving field of deep learning, specialized models have driven significant advancements in tasks such as computer vision and natural language processing. However, this specialization leads to a fragmented ecosystem where models lack the adaptability for broader applications. To overcome this, we introduce AutoFusion, an innovative framework that fuses distinct model parameters(with the same architecture) for multi-task learning without pre-trained checkpoints. Using an unsupervised, end-to-end approach, AutoFusion dynamically permutes model parameters at each layer, optimizing the combination through a loss-minimization process that does not require labeled data. We validate AutoFusion's effectiveness through experiments on commonly used benchmark datasets, demonstrating superior performance over established methods like Weight Interpolation, Git Re-Basin, and ZipIt. Our framework offers a scalable and flexible solution for model integration, positioning it as a powerful tool for future research and practical applications.

In recent years, multimodal large language models (MLLMs) have significantly advanced, integrating more modalities into diverse applications. However, the lack of explainability remains a major barrier to their use in scenarios requiring decision transparency. Current neuron-level explanation paradigms mainly focus on knowledge localization or language-and domain-specific analyses, leaving the exploration of multimodality largely unaddressed. To tackle these challenges, we propose MINER, a transferable framework for mining modality-specific neurons (MSNs) in MLLMs, which comprises four stages: modality separation, importance score calculation, importance score aggregation, modality-specific neuron selection. Extensive experiments across six benchmarks and two representative MLLMs show that (I) deactivating ONLY 2% of MSNs significantly reduces MLLMs performance (0.56 0.24 for Qwen2-VL, 0.69 0.31 for Qwen2-Audio), (II) different modalities mainly converge in the lower layers, (III) MSNs influence how key information from various modalities converges to the last token, (IV)two intriguing phenomena worth further investigation, i.e., semantic probing and semantic telomeres. The source code is available at this URL. Xiao et al., 2024; Yan et al., 2024), exemplified However, their black-box nature presents challenges, particularly in fields like medical studies (González-Alday et al., 2023), where interpretability is essential. Understanding the decision-making process is vital, making explainability a central focus of ongoing research (Tjoa & Guan, 2020; Zhao et al., 2024). Numerous studies have sought to understand how knowledge is stored in models (Sukhbaatar et al., 2019; Dai et al., 2021; Meng et al., 2022a; Chen et al., 2024a) and how this information influences decision-making (Geva et al., 2020; Petroni et al., 2019). For example, Dai et al. (2021); Geva et al. (2020) investigate knowledge storage mechanisms, while Wendler et al. (2024); Zhang et al. (2024) provide insights into layer-level explainability.

4D millimeter-wave (MMW) radar, which provides both height information and dense point cloud data over 3D MMW radar, has become increasingly popular in 3D object detection. In recent years, radar-vision fusion models have demonstrated performance close to that of LiDAR-based models, offering advantages in terms of lower hardware costs and better resilience in extreme conditions. However, many radar-vision fusion models treat radar as a sparse LiDAR, underutilizing radar-specific information. Additionally, these multi-modal networks are often sensitive to the failure of a single modality, particularly vision. To address these challenges, we propose the Radar Depth Lift-Splat-Shoot (RDL) module, which integrates radar-specific data into the depth prediction process, enhancing the quality of visual Bird-Eye View (BEV) features. We further introduce a Unified Feature Fusion (UFF) approach that extracts BEV features across different modalities using shared module. To assess the robustness of multi-modal models, we develop a novel Failure Test (FT) ablation experiment, which simulates vision modality failure by injecting Gaussian noise. We conduct extensive experiments on the View-of-Delft (VoD) and TJ4D datasets. The results demonstrate that our proposed Unified BEVFusion (UniBEVFusion) network significantly outperforms state-of-the-art models on the TJ4D dataset, with improvements of 1.44 in 3D and 1.72 in BEV object detection accuracy.