This study explores the application of machine learning-based genetic linguistics for identifying heavy metal response genes in rice (Oryza sativa). By integrating convolutional neural networks and random forest algorithms, we developed a hybrid model capable of extracting and learning meaningful features from gene sequences, such as k-mer frequencies and physicochemical properties. The model was trained and tested on datasets of genes, achieving high predictive performance (precision: 0.89, F1-score: 0.82). RNA-seq and qRT-PCR experiments conducted on rice leaves which exposed to Hg0, revealed differential expression of genes associated with heavy metal responses, which validated the model's predictions. Co-expression network analysis identified 103 related genes, and a literature review indicated that these genes are highly likely to be involved in heavy metal-related biological processes. By integrating and comparing the analysis results with those of differentially expressed genes (DEGs), the validity of the new machine learning method was further demonstrated. This study highlights the efficacy of combining machine learning with genetic linguistics for large-scale gene prediction. It demonstrates a cost-effective and efficient approach for uncovering molecular mechanisms underlying heavy metal responses, with potential applications in developing stress-tolerant crop varieties.

General matrix-matrix multiplication (GEMM) is a cornerstone of AI computations, making tensor processing engines (TPEs) increasingly critical in GPUs and domain-specific architectures. Existing architectures primarily optimize dataflow or operand reuse strategies. However, considering the interaction between matrix multiplication and multiply-accumulators (MACs) offers greater optimization potential. This work introduces a novel hardware perspective on matrix multiplication, focusing on the bit-weight dimension of MACs. We propose a finer-grained TPE notation using matrix triple loops as an example, introducing new methods for designing and optimizing PE microarchitectures. Based on this notation and its transformations, we propose four optimization techniques that improve timing, area, and power consumption. Implementing our design in RTL using the SMIC-28nm process, we evaluate its effectiveness across four classic TPE architectures: systolic array, 3D-Cube, multiplier-adder tree, and 2D-Matrix. Our techniques achieve area efficiency improvements of 1.27x, 1.28x, 1.56x, and 1.44x, and energy efficiency gains of 1.04x, 1.56x, 1.49x, and 1.20x, respectively. Applied to a bit-slice architecture, our approach achieves a 12.10x improvement in energy efficiency and 2.85x in area efficiency compared to Laconic. Our Verilog HDL code, along with timing, area, and power reports, is available at https://github.com/wqzustc/High-Performance-Tensor-Processing-Engines

Diffusion models have emerged as powerful tools for generative tasks, producing high-quality outputs across diverse domains. However, how the generated data responds to the initial noise perturbation in diffusion models remains under-explored, which hinders understanding the controllability of the sampling process. In this work, we first observe an interesting phenomenon: the relationship between the change of generation outputs and the scale of initial noise perturbation is highly linear through the diffusion ODE sampling. Then we provide both theoretical and empirical study to justify this linearity property of this input-output (noise-generation data) relationship. Inspired by these new insights, we propose a novel Controllable and Constrained Sampling method (CCS) together with a new controller algorithm for diffusion models to sample with desired statistical properties while preserving good sample quality. We perform extensive experiments to compare our proposed sampling approach with other methods on both sampling controllability and sampled data quality. Results show that our CCS method achieves more precisely controlled sampling while maintaining superior sample quality and diversity.

In recent years, remarkable advancements in artificial intelligence-generated content (AIGC) have been achieved in the fields of image synthesis and text generation, generating content comparable to that produced by humans. However, the quality of AI-generated music has not yet reached this standard, primarily due to the challenge of effectively controlling musical emotions and ensuring high-quality outputs. This paper presents a generalized symbolic music generation framework, XMusic, which supports flexible prompts (i.e., images, videos, texts, tags, and humming) to generate emotionally controllable and high-quality symbolic music. XMusic consists of two core components, XProjector and XComposer. XProjector parses the prompts of various modalities into symbolic music elements (i.e., emotions, genres, rhythms and notes) within the projection space to generate matching music. XComposer contains a Generator and a Selector. The Generator generates emotionally controllable and melodious music based on our innovative symbolic music representation, whereas the Selector identifies high-quality symbolic music by constructing a multi-task learning scheme involving quality assessment, emotion recognition, and genre recognition tasks. In addition, we build XMIDI, a large-scale symbolic music dataset that contains 108,023 MIDI files annotated with precise emotion and genre labels. Objective and subjective evaluations show that XMusic significantly outperforms the current state-of-the-art methods with impressive music quality. Our XMusic has been awarded as one of the nine Highlights of Collectibles at WAIC 2023. The project homepage of XMusic is https://xmusic-project.github.io.

Time series forecasting plays a critical role in various real-world applications, including energy consumption prediction, disease transmission monitoring, and weather forecasting. Although substantial progress has been made in time series forecasting, most existing methods rely on a centralized training paradigm, where large amounts of data are collected from distributed devices (e.g., sensors, wearables) to a central cloud server. However, this paradigm has overloaded communication networks and raised privacy concerns. Federated learning, a popular privacy-preserving technique, enables collaborative model training across distributed data sources. However, directly applying federated learning to time series forecasting often yields suboptimal results, as time series data generated by different devices are inherently heterogeneous. In this paper, we propose a novel framework, Fed-TREND, to address data heterogeneity by generating informative synthetic data as auxiliary knowledge carriers. Specifically, Fed-TREND generates two types of synthetic data. The first type of synthetic data captures the representative distribution information from clients' uploaded model updates and enhances clients' local training consensus. The second kind of synthetic data extracts long-term influence insights from global model update trajectories and is used to refine the global model after aggregation. Fed-TREND is compatible with most time series forecasting models and can be seamlessly integrated into existing federated learning frameworks to improve prediction performance. Extensive experiments on eight datasets, using several federated learning baselines and four popular time series forecasting models, demonstrate the effectiveness and generalizability of Fed-TREND.

In recent years, with the significant evolution of multi-modal large models, many recommender researchers realized the potential of multi-modal information for user interest modeling. In industry, a wide-used modeling architecture is a cascading paradigm: (1) first pre-training a multi-modal model to provide omnipotent representations for downstream services; (2) The downstream recommendation model takes the multi-modal representation as additional input to fit real user-item behaviours. Although such paradigm achieves remarkable improvements, however, there still exist two problems that limit model performance: (1) Representation Unmatching: The pre-trained multi-modal model is always supervised by the classic NLP/CV tasks, while the recommendation models are supervised by real user-item interaction. As a result, the two fundamentally different tasks' goals were relatively separate, and there was a lack of consistent objective on their representations; (2) Representation Unlearning: The generated multi-modal representations are always stored in cache store and serve as extra fixed input of recommendation model, thus could not be updated by recommendation model gradient, further unfriendly for downstream training. Inspired by the two difficulties challenges in downstream tasks usage, we introduce a quantitative multi-modal framework to customize the specialized and trainable multi-modal information for different downstream models.

Dynamic and interactive traffic scenarios pose significant challenges for autonomous driving systems. Reinforcement learning (RL) offers a promising approach by enabling the exploration of driving policies beyond the constraints of pre-collected datasets and predefined conditions, particularly in complex environments. However, a critical challenge lies in effectively extracting spatial and temporal features from sequences of high-dimensional, multi-modal observations while minimizing the accumulation of errors over time. Additionally, efficiently guiding large-scale RL models to converge on optimal driving policies without frequent failures during the training process remains tricky. We propose an end-to-end model-based RL algorithm named Ramble to address these issues. Ramble processes multi-view RGB images and LiDAR point clouds into low-dimensional latent features to capture the context of traffic scenarios at each time step. A transformer-based architecture is then employed to model temporal dependencies and predict future states. By learning a dynamics model of the environment, Ramble can foresee upcoming traffic events and make more informed, strategic decisions. Our implementation demonstrates that prior experience in feature extraction and decision-making plays a pivotal role in accelerating the convergence of RL models toward optimal driving policies. Ramble achieves state-of-the-art performance regarding route completion rate and driving score on the CARLA Leaderboard 2.0, showcasing its effectiveness in managing complex and dynamic traffic situations.

In sampling tasks, it is common for target distributions to be known up to a normalising constant. However, in many situations, evaluating even the unnormalised distribution can be costly or infeasible. This issue arises in scenarios such as sampling from the Bayesian posterior for tall datasets and the 'doubly-intractable' distributions. In this paper, we begin by observing that seemingly different Markov chain Monte Carlo (MCMC) algorithms, such as the exchange algorithm, PoissonMH, and TunaMH, can be unified under a simple common procedure. We then extend this procedure into a novel framework that allows the use of auxiliary variables in both the proposal and acceptance-rejection steps. We develop the theory of the new framework, applying it to existing algorithms to simplify and extend their results. Several new algorithms emerge from this framework, with improved performance demonstrated on both synthetic and real datasets.

While language models have made many milestones in text inference and classification tasks, they remain susceptible to adversarial attacks that can lead to unforeseen outcomes. Existing works alleviate this problem by equipping language models with defense patches. However, these defense strategies often rely on impractical assumptions or entail substantial sacrifices in model performance. Consequently, enhancing the resilience of the target model using such defense mechanisms is a formidable challenge. This paper introduces an innovative model for robust text inference and classification, built upon diffusion models (ROIC-DM). Benefiting from its training involving denoising stages, ROIC-DM inherently exhibits greater robustness compared to conventional language models. Moreover, ROIC-DM can attain comparable, and in some cases, superior performance to language models, by effectively incorporating them as advisory components. Extensive experiments conducted with several strong textual adversarial attacks on three datasets demonstrate that (1) ROIC-DM outperforms traditional language models in robustness, even when the latter are fortified with advanced defense mechanisms; (2) ROIC-DM can achieve comparable and even better performance than traditional language models by using them as advisors.

Simulators play a crucial role in autonomous driving, offering significant time, cost, and labor savings. Over the past few years, the number of simulators for autonomous driving has grown substantially. However, there is a growing concern about the validity of algorithms developed and evaluated in simulators, indicating a need for a thorough analysis of the development status of the simulators. To bridge the gap in research, this paper analyzes the evolution of simulators and explains how the functionalities and utilities have developed. Then, the existing simulators are categorized based on their task applicability, providing researchers with a taxonomy to swiftly assess a simulator's suitability for specific tasks. Recommendations for select simulators are presented, considering factors such as accessibility, maintenance status, and quality. Recognizing potential hazards in simulators that could impact the confidence of simulation experiments, the paper dedicates substantial effort to identifying and justifying critical issues in actively maintained open-source simulators. Moreover, the paper reviews potential solutions to address these issues, serving as a guide for enhancing the credibility of simulators.