Facial Action Units (AU) is a vital concept in the realm of affective computing, and AU detection has always been a hot research topic. Existing methods suffer from overfitting issues due to the utilization of a large number of learnable parameters on scarce AU-annotated datasets or heavy reliance on substantial additional relevant data. Parameter-Efficient Transfer Learning (PETL) provides a promising paradigm to address these challenges, whereas its existing methods lack design for AU characteristics. Therefore, we innovatively investigate PETL paradigm to AU detection, introducing AUFormer and proposing a novel Mixture-of-Knowledge Expert (MoKE) collaboration mechanism. An individual MoKE specific to a certain AU with minimal learnable parameters first integrates personalized multi-scale and correlation knowledge. Then the MoKE collaborates with other MoKEs in the expert group to obtain aggregated information and inject it into the frozen Vision Transformer (ViT) to achieve parameter-efficient AU detection. Additionally, we design a Margin-truncated Difficulty-aware Weighted Asymmetric Loss (MDWA-Loss), which can encourage the model to focus more on activated AUs, differentiate the difficulty of unactivated AUs, and discard potential mislabeled samples. Extensive experiments from various perspectives, including within-domain, cross-domain, data efficiency, and micro-expression domain, demonstrate AUFormer's state-of-the-art performance and robust generalization abilities without relying on additional relevant data. The code for AUFormer is available at https://github.com/yuankaishen2001/AUFormer.

Multimodal large language models (MLLMs) are designed to process and integrate information from multiple sources, such as text, speech, images, and videos. Despite its success in language understanding, it is critical to evaluate the performance of downstream tasks for better human-centric applications. This paper assesses the application of MLLMs with 5 crucial abilities for affective computing, spanning from visual affective tasks and reasoning tasks. The results show that \gpt has high accuracy in facial action unit recognition and micro-expression detection while its general facial expression recognition performance is not accurate. We also highlight the challenges of achieving fine-grained micro-expression recognition and the potential for further study and demonstrate the versatility and potential of \gpt for handling advanced tasks in emotion recognition and related fields by integrating with task-related agents for more complex tasks, such as heart rate estimation through signal processing. In conclusion, this paper provides valuable insights into the potential applications and challenges of MLLMs in human-centric computing. Our interesting examples are at https://github.com/EnVision-Research/GPT4Affectivity.