The abundance of intestinal flora is closely related to human diseases, but diseases are not caused by a single gut microbe. Instead, they result from the complex interplay of numerous microbial entities. This intricate and implicit connection among gut microbes poses a significant challenge for disease prediction using abundance information from OTU data. Recently, several methods have shown potential in predicting corresponding diseases. However, these methods fail to learn the inner association among gut microbes from different hosts, leading to unsatisfactory performance. In this paper, we present a novel architecture, Unsupervised Multi-graph Merge Adversarial Network (UMMAN). UMMAN can obtain the embeddings of nodes in the Multi-Graph in an unsupervised scenario, so that it helps learn the multiplex association. Our method is the first to combine Graph Neural Network with the task of intestinal flora disease prediction. We employ complex relation-types to construct the Original-Graph and disrupt the relationships among nodes to generate corresponding Shuffled-Graph. We introduce the Node Feature Global Integration (NFGI) module to represent the global features of the graph. Furthermore, we design a joint loss comprising adversarial loss and hybrid attention loss to ensure that the real graph embedding aligns closely with the Original-Graph and diverges from the Shuffled-Graph. Comprehensive experiments on five classical OTU gut microbiome datasets demonstrate the effectiveness and stability of our method. (We will release our code soon.)

Partially supervised text classification has received great research attention since it only uses positive and unlabeled examples as training data. This problem can be solved by automatically labeling some negative (and more positive) examples from unlabeled examples before training a text classifier. But it is difficult to guarantee both high quality and quantity of the new labeled examples. In this paper, a multi-level example based learning method for partially supervised text classification is proposed, which can make full use of all unlabeled examples. A heuristic method is proposed to assign possible labels to unlabeled examples and partition them into multiple levels according to their labeling confidence. A text classifier is trained on these multi-level examples using weighted support vector machines. Experiments show that the multi-level example based learning method is effective for partially supervised text classification, and outperforms the existing popular methods such as Biased-SVM, ROC-SVM, S-EM and WL.