Video large language models (ViLLMs) excel in general video understanding, e.g., recognizing activities like talking and eating, but struggle with identity-aware comprehension, such as "Wilson is receiving chemotherapy" or "Tom is discussing with Sarah", limiting their applicability in smart healthcare and smart home environments. To address this limitation, we propose a one-shot learning framework PVChat, the first personalized ViLLM that enables subject-aware question answering (QA) from a single video for each subject. Our approach optimizes a Mixture-of-Heads (MoH) enhanced ViLLM on a synthetically augmented video-QA dataset, leveraging a progressive image-to-video learning strategy. Specifically, we introduce an automated augmentation pipeline that synthesizes identity-preserving positive samples and retrieves hard negatives from existing video corpora, generating a diverse training dataset with four QA types: existence, appearance, action, and location inquiries. To enhance subject-specific learning, we propose a ReLU Routing MoH attention mechanism, alongside two novel objectives: (1) Smooth Proximity Regularization for progressive learning through exponential distance scaling and (2) Head Activation Enhancement for balanced attention routing. Finally, we adopt a two-stage training strategy, transitioning from image pre-training to video fine-tuning, enabling a gradual learning process from static attributes to dynamic representations. We evaluate PVChat on diverse datasets covering medical scenarios, TV series, anime, and real-world footage, demonstrating its superiority in personalized feature understanding after learning from a single video, compared to state-of-the-art ViLLMs.

Recent advancements in implicit 3D reconstruction methods, e.g., neural rendering fields and Gaussian splatting, have primarily focused on novel view synthesis of static or dynamic objects with continuous motion states. However, these approaches struggle to efficiently model a human-interactive object with n movable parts, requiring 2^n separate models to represent all discrete states. To overcome this limitation, we propose Inter3D, a new benchmark and approach for novel state synthesis of human-interactive objects. We introduce a self-collected dataset featuring commonly encountered interactive objects and a new evaluation pipeline, where only individual part states are observed during training, while part combination states remain unseen. We also propose a strong baseline approach that leverages Space Discrepancy Tensors to efficiently modelling all states of an object. To alleviate the impractical constraints on camera trajectories across training states, we propose a Mutual State Regularization mechanism to enhance the spatial density consistency of movable parts. In addition, we explore two occupancy grid sampling strategies to facilitate training efficiency. We conduct extensive experiments on the proposed benchmark, showcasing the challenges of the task and the superiority of our approach.

Despite being an essential tool across engineering and finance, Monte Carlo simulation can be computationally intensive, especially in largescale, path-dependent problems that hinder straightforward parallelization. A natural alternative is to replace simulation with machine learning or surrogate prediction, though this introduces challenges in understanding the resulting errors. We introduce a Prediction-Enhanced Monte Carlo (PEMC) framework where we leverage machine learning prediction as control variates, thus maintaining unbiased evaluations instead of the direct use of ML predictors. Traditional control variate methods require knowledge of means and focus on per-sample variance reduction. In contrast, PEMC aims at overall cost-aware variance reduction, eliminating the need for mean knowledge. PEMC leverages pre-trained neural architectures to construct effective control variates and replaces computationally expensive sample-path generation with efficient neural network evaluations. This allows PEMC to address scenarios where no good control variates are known.

Cooperative path planning, a crucial aspect of multi-agent systems research, serves a variety of sectors, including military, agriculture, and industry. Many existing algorithms, however, come with certain limitations, such as simplified kinematic models and inadequate support for multiple group scenarios. Focusing on the planning problem associated with a nonholonomic Ackermann model for Unmanned Ground Vehicles (UGV), we propose a leaderless, hierarchical Search-Based Cooperative Motion Planning (SCMP) method. The high-level utilizes a binary conflict search tree to minimize runtime, while the low-level fabricates kinematically feasible, collision-free paths that are shape-constrained. Our algorithm can adapt to scenarios featuring multiple groups with different shapes, outlier agents, and elaborate obstacles. We conduct algorithm comparisons, performance testing, simulation, and real-world testing, verifying the effectiveness and applicability of our algorithm. The implementation of our method will be open-sourced at https://github.com/WYCUniverStar/SCMP.

One way to quantify exposure to air pollution and its constituents in epidemiologic studies is to use an individual's nearest monitor. This strategy results in potential inaccuracy in the actual personal exposure, introducing bias in estimating the health effects of air pollution and its constituents, especially when evaluating the causal effects of correlated multi-pollutant constituents measured with correlated error. This paper addresses estimation and inference for the causal effect of one constituent in the presence of other PM2.5 constituents, accounting for measurement error and correlations. We used a linear regression calibration model, fitted with generalized estimating equations in an external validation study, and extended a double/debiased machine learning (DML) approach to correct for measurement error and estimate the effect of interest in the main study. We demonstrated that the DML estimator with regression calibration is consistent and derived its asymptotic variance. Simulations showed that the proposed estimator reduced bias and attained nominal coverage probability across most simulation settings. We applied this method to assess the causal effects of PM2.5 constituents on cognitive function in the Nurses' Health Study and identified two PM2.5 constituents, Br and Mn, that showed a negative causal effect on cognitive function after measurement error correction.

Histopathology image analysis plays a crucial role in cancer diagnosis. However, training a clinically applicable segmentation algorithm requires pathologists to engage in labour-intensive labelling. In contrast, weakly supervised learning methods, which only require coarse-grained labels at the image level, can significantly reduce the labeling efforts. Unfortunately, while these methods perform reasonably well in slide-level prediction, their ability to locate cancerous regions, which is essential for many clinical applications, remains unsatisfactory. Previously, we proposed CAMEL, which achieves comparable results to those of fully supervised baselines in pixel-level segmentation. However, CAMEL requires 1,280x1,280 image-level binary annotations for positive WSIs. Here, we present CAMEL2, by introducing a threshold of the cancerous ratio for positive bags, it allows us to better utilize the information, consequently enabling us to scale up the image-level setting from 1,280x1,280 to 5,120x5,120 while maintaining the accuracy. Our results with various datasets, demonstrate that CAMEL2, with the help of 5,120x5,120 image-level binary annotations, which are easy to annotate, achieves comparable performance to that of a fully supervised baseline in both instance- and slide-level classifications.