Deformable object manipulation in robotics presents significant challenges due to uncertainties in component properties, diverse configurations, visual interference, and ambiguous prompts. These factors complicate both perception and control tasks. To address these challenges, we propose a novel method for One-Shot Affordance Grounding of Deformable Objects (OS-AGDO) in egocentric organizing scenes, enabling robots to recognize previously unseen deformable objects with varying colors and shapes using minimal samples. Specifically, we first introduce the Deformable Object Semantic Enhancement Module (DefoSEM), which enhances hierarchical understanding of the internal structure and improves the ability to accurately identify local features, even under conditions of weak component information. Next, we propose the ORB-Enhanced Keypoint Fusion Module (OEKFM), which optimizes feature extraction of key components by leveraging geometric constraints and improves adaptability to diversity and visual interference. Additionally, we propose an instance-conditional prompt based on image data and task context, effectively mitigates the issue of region ambiguity caused by prompt words. To validate these methods, we construct a diverse real-world dataset, AGDDO15, which includes 15 common types of deformable objects and their associated organizational actions. Experimental results demonstrate that our approach significantly outperforms state-of-the-art methods, achieving improvements of 6.2%, 3.2%, and 2.9% in KLD, SIM, and NSS metrics, respectively, while exhibiting high generalization performance. Source code and benchmark dataset will be publicly available at https://github.com/Dikay1/OS-AGDO.

The potential of artificial intelligence (AI) in digital pathology is limited by technical inconsistencies in the production of whole slide images (WSIs), leading to degraded AI performance and posing a challenge for widespread clinical application as fine-tuning algorithms for each new site is impractical. Changes in the imaging workflow can also lead to compromised diagnoses and patient safety risks. We evaluated whether physical color calibration of scanners can standardize WSI appearance and enable robust AI performance. We employed a color calibration slide in four different laboratories and evaluated its impact on the performance of an AI system for prostate cancer diagnosis on 1,161 WSIs. Color standardization resulted in consistently improved AI model calibration and significant improvements in Gleason grading performance. The study demonstrates that physical color calibration provides a potential solution to the variation introduced by different scanners, making AI-based cancer diagnostics more reliable and applicable in clinical settings.