Accurate tissue point tracking in endoscopic videos is critical for robotic-assisted surgical navigation and scene understanding, but remains challenging due to complex deformations, instrument occlusion, and the scarcity of dense trajectory annotations. Existing methods struggle with long-term tracking under these conditions due to limited feature utilization and annotation dependence. We present Endo-TTAP, a novel framework addressing these challenges through: (1) A Multi-Facet Guided Attention (MFGA) module that synergizes multi-scale flow dynamics, DINOv2 semantic embeddings, and explicit motion patterns to jointly predict point positions with uncertainty and occlusion awareness; (2) A two-stage curriculum learning strategy employing an Auxiliary Curriculum Adapter (ACA) for progressive initialization and hybrid supervision. Stage I utilizes synthetic data with optical flow ground truth for uncertainty-occlusion regularization, while Stage II combines unsupervised flow consistency and semi-supervised learning with refined pseudo-labels from off-the-shelf trackers. Extensive validation on two MICCAI Challenge datasets and our collected dataset demonstrates that Endo-TTAP achieves state-of-the-art performance in tissue point tracking, particularly in scenarios characterized by complex endoscopic conditions. The source code and dataset will be available at https://anonymous.4open.science/r/Endo-TTAP-36E5.

Control barrier function (CBF)-based methods provide the minimum modification necessary to formally guarantee safety in the context of quadratic programming, and strict safety guarantee for safety critical systems. However, most CBF-related derivatives myopically focus on present safety at each time step, a reasoning over a look-ahead horizon is exactly missing. In this paper, a predictive safety matrix is constructed. We then consolidate the safety condition based on the smallest eigenvalue of the proposed safety matrix. A predefined deconfliction strategy of motion paths is embedded into the trajectory tracking module to manage deadlock conflicts, which computes the deadlock escape velocity with the minimum attitude angle. Comparison results show that the introduction of the predictive term is robust for measurement uncertainty and is immune to oscillations. The proposed deadlock avoidance method avoids a large detour, without obvious stagnation.

Automated drug discovery offers significant potential for accelerating the development of novel therapeutics by substituting labor-intensive human workflows with machine-driven processes. However, molecules generated by artificial intelligence may unintentionally infringe on existing patents, posing legal and financial risks that impede the full automation of drug discovery pipelines. This paper introduces PatentFinder, a novel multi-agent and tool-enhanced intelligence system that can accurately and comprehensively evaluate small molecules for patent infringement. PatentFinder features five specialized agents that collaboratively analyze patent claims and molecular structures with heuristic and model-based tools, generating interpretable infringement reports. To support systematic evaluation, we curate MolPatent-240, a benchmark dataset tailored for patent infringement assessment algorithms. On this benchmark, PatentFinder outperforms baseline methods that rely solely on large language models or specialized chemical tools, achieving a 13.8% improvement in F1-score and a 12% increase in accuracy. Additionally, PatentFinder autonomously generates detailed and interpretable patent infringement reports, showcasing enhanced accuracy and improved interpretability. The high accuracy and interpretability of PatentFinder make it a valuable and reliable tool for automating patent infringement assessments, offering a practical solution for integrating patent protection analysis into the drug discovery pipeline.

One of the pivotal challenges in a multi-robot system is how to give attention to accuracy and efficiency while ensuring safety. Prior arts cannot strictly guarantee collision-free for an arbitrarily large number of robots or the results are considerably conservative. Smoothness of the avoidance trajectory also needs to be further optimized. This paper proposes an accelerationactuated simultaneous obstacle avoidance and trajectory tracking method for arbitrarily large teams of robots, that provides a nonconservative collision avoidance strategy and gives approaches for deadlock avoidance. We propose two ways of deadlock resolution, one involves incorporating an auxiliary velocity vector into the error function of the trajectory tracking module, which is proven to have no influence on global convergence of the tracking error. Furthermore, unlike the traditional methods that they address conflicts after a deadlock occurs, our decision-making mechanism avoids the near-zero velocity, which is much more safer and efficient in crowed environments. Extensive comparison show that the proposed method is superior to the existing studies when deployed in a large-scale robot system, with minimal invasiveness.

Host-response-based diagnostics can improve the accuracy of diagnosing bacterial and viral infections, thereby reducing inappropriate antibiotic prescriptions. However, the existing cohorts with limited sample size and coarse infections types are unable to support the exploration of an accurate and generalizable diagnostic model. Here, we curate the largest infection host-response transcriptome data, including 11,247 samples across 89 blood transcriptome datasets from 13 countries and 21 platforms. We build a diagnostic model for pathogen prediction starting from a pan-infection model as foundation (AUC = 0.97) based on the pan-infection dataset. Then, we utilize knowledge distillation to efficiently transfer the insights from this "teacher" model to four lightweight pathogen "student" models, i.e., staphylococcal infection (AUC = 0.99), streptococcal infection (AUC = 0.94), HIV infection (AUC = 0.93), and RSV infection (AUC = 0.94), as well as a sepsis "student" model (AUC = 0.99). The proposed knowledge distillation framework not only facilitates the diagnosis of pathogens using pan-infection data, but also enables an across-disease study from pan-infection to sepsis. Moreover, the framework enables high-degree lightweight design of diagnostic models, which is expected to be adaptively deployed in clinical settings.

Air-ground collaborative robots have shown great potential in the field of fire and rescue, which can quickly respond to rescue needs and improve the efficiency of task execution. Mapping and navigation, as the key foundation for air-ground collaborative robots to achieve efficient task execution, have attracted a great deal of attention. This growing interest in collaborative robot mapping and navigation is conducive to improving the intelligence of fire and rescue task execution, but there has been no comprehensive investigation of this field to highlight their strengths. In this paper, we present a systematic review of the ground-to-ground cooperative robots for fire and rescue from a new perspective of mapping and navigation. First, an air-ground collaborative robots framework for fire and rescue missions based on unmanned aerial vehicle (UAV) mapping and unmanned ground vehicle (UGV) navigation is introduced. Then, the research progress of mapping and navigation under this framework is systematically summarized, including UAV mapping, UAV/UGV co-localization, and UGV navigation, with their main achievements and limitations. Based on the needs of fire and rescue missions, the collaborative robots with different numbers of UAVs and UGVs are classified, and their practicality in fire and rescue tasks is elaborated, with a focus on the discussion of their merits and demerits. In addition, the application examples of air-ground collaborative robots in various firefighting and rescue scenarios are given. Finally, this paper emphasizes the current challenges and potential research opportunities, rounding up references for practitioners and researchers willing to engage in this vibrant area of air-ground collaborative robots.

Robots are increasingly deployed in dynamic and crowded environments, such as urban areas and shopping malls, where efficient and robust navigation is crucial. Traditional risk-based motion planning algorithms face challenges in such scenarios due to the lack of a well-defined search region, leading to inefficient exploration in irrelevant areas. While bi-directional and multi-directional search strategies can improve efficiency, they still result in significant unnecessary exploration. This article introduces the Neural Adaptive Multi-directional Risk-based Rapidly-exploring Random Tree (NAMR-RRT) to address these limitations. NAMR-RRT integrates neural network-generated heuristic regions to dynamically guide the exploration process, continuously refining the heuristic region and sampling rates during the planning process. This adaptive feature significantly enhances performance compared to neural-based methods with fixed heuristic regions and sampling rates. NAMR-RRT improves planning efficiency, reduces trajectory length, and ensures higher success by focusing the search on promising areas and continuously adjusting to environments. The experiment results from both simulations and real-world applications demonstrate the robustness and effectiveness of our proposed method in navigating dynamic environments. A website about this work is available at https://sites.google.com/view/namr-rrt.

Human-robot interaction (HRI) encompasses a wide range of collaborative tasks, with handover being one of the most fundamental. As robots become more integrated into human environments, the potential for service robots to assist in handing objects to humans is increasingly promising. In robot-to-human (R2H) handover, selecting the optimal grasp is crucial for success, as it requires avoiding interference with the humans preferred grasp region and minimizing intrusion into their workspace. Existing methods either inadequately consider geometric information or rely on data-driven approaches, which often struggle to generalize across diverse objects. To address these limitations, we propose a novel zero-shot system that combines semantic and geometric information to generate optimal handover grasps. Our method first identifies grasp regions using semantic knowledge from vision-language models (VLMs) and, by incorporating customized visual prompts, achieves finer granularity in region grounding. A grasp is then selected based on grasp distance and approach angle to maximize human ease and avoid interference. We validate our approach through ablation studies and real-world comparison experiments. Results demonstrate that our system improves handover success rates and provides a more user-preferred interaction experience. Videos, appendixes and more are available at https://sites.google.com/view/vlm-handover/.

Accurately predicting the trajectory of surrounding vehicles is a critical challenge for autonomous vehicles. In complex traffic scenarios, there are two significant issues with the current autonomous driving system: the cognitive uncertainty of prediction and the lack of risk awareness, which limit the further development of autonomous driving. To address this challenge, we introduce a novel trajectory prediction model that incorporates insights and principles from driving behavior, ethical decision-making, and risk assessment. Based on joint prediction, our model consists of interaction, intention, and risk assessment modules. The dynamic variation of interaction between vehicles can be comprehensively captured at each timestamp in the interaction module. Based on interaction information, our model considers primary intentions for vehicles to enhance the diversity of trajectory generation. The optimization of predicted trajectories follows the advanced risk-aware decision-making principles. Experimental results are evaluated on the DeepAccident dataset; our approach shows its remarkable prediction performance on normal and accident scenarios and outperforms the state-of-the-art algorithms by at least 28.9\% and 26.5\%, respectively. The proposed model improves the proficiency and adaptability of trajectory prediction in complex traffic scenarios. The code for the proposed model is available at https://sites.google.com/view/ir-prediction.

Recent breakthroughs in Large Language Models (LLMs) have revolutionized natural language understanding and generation, sparking significant interest in applying them to scientific literature analysis. However, existing benchmarks fail to adequately evaluate the proficiency of LLMs in this domain, particularly in scenarios requiring higher-level abilities beyond mere memorization and the handling of multimodal data. In response to this gap, we introduce SciAssess, a benchmark specifically designed for the comprehensive evaluation of LLMs in scientific literature analysis. SciAssess aims to thoroughly assess the efficacy of LLMs by focusing on their capabilities in Memorization (L1), Comprehension (L2), and Analysis \& Reasoning (L3). It encompasses a variety of tasks drawn from diverse scientific fields, including fundamental science, alloy materials, biomedicine, drug discovery, and organic materials. To ensure the reliability of SciAssess, rigorous quality control measures have been implemented, ensuring accuracy, anonymization, and compliance with copyright standards. SciAssess evaluates 11 LLMs, including GPT, Claude, and Gemini, highlighting their strengths and areas for improvement. This evaluation supports the ongoing development of LLM applications in the analysis of scientific literature. SciAssess and its resources are available at \url{https://sci-assess.github.io/}.