Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose challenges to accurate and consistent lesion segmentation. In clinical practice, radiologists commonly use the sub-sequence feature, i.e. the difference between post contrast-enhanced T1-weighted (post) and pre-contrast-enhanced (pre) sequences, to locate lesions. Inspired by this, we propose a residual fusion method to learn subsequence representation for MRI lesion segmentation. Specifically, we iteratively and adaptively fuse features from pre- and post-contrast sequences at multiple resolutions, using dynamic weights to achieve optimal fusion and address diverse lesion enhancement patterns. Our method achieves state-of-the-art performances on BraTS2023 dataset for brain tumor segmentation and our in-house breast MRI dataset for breast lesion segmentation. Our method is clinically inspired and has the potential to facilitate lesion segmentation in various applications.

We introduce UnrealZoo, a rich collection of photo-realistic 3D virtual worlds built on Unreal Engine, designed to reflect the complexity and variability of the open worlds. Additionally, we offer a variety of playable entities for embodied AI agents. Based on UnrealCV, we provide a suite of easy-to-use Python APIs and tools for various potential applications, such as data collection, environment augmentation, distributed training, and benchmarking. We optimize the rendering and communication efficiency of UnrealCV to support advanced applications, such as multi-agent interaction. Our experiments benchmark agents in various complex scenes, focusing on visual navigation and tracking, which are fundamental capabilities for embodied visual intelligence. The results yield valuable insights into the advantages of diverse training environments for reinforcement learning (RL) agents and the challenges faced by current embodied vision agents, including those based on RL and large vision-language models (VLMs), in open worlds. These challenges involve latency in closed-loop control in dynamic scenes and reasoning about 3D spatial structures in unstructured terrain.

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these diverse series to form a coherent analysis presents significant challenges, such as differing spatial resolutions and contrast patterns meanwhile requiring extensive annotated data, which is scarce in clinical practice. Due to these issues, we introduce a novel Cross-Series Masking (CSM) Strategy for effectively learning MRI representation in a self-supervised manner. Specifically, CSM commences by randomly sampling a subset of regions and series, which are then strategically masked. In the training process, the cross-series representation is learned by utilizing the unmasked data to reconstruct the masked portions. This process not only integrates information across different series but also facilitates the ability to model both intra-series and inter-series correlations and complementarities. With the learned representation, the downstream tasks like segmentation and classification are also enhanced. Taking brain tissue segmentation, breast tumor benign/malignant classification, and prostate cancer diagnosis as examples, our method achieves state-of-the-art performance on both public and in-house datasets.

Embodied visual tracking is to follow a target object in dynamic 3D environments using an agent's egocentric vision. This is a vital and challenging skill for embodied agents. However, existing methods suffer from inefficient training and poor generalization. In this paper, we propose a novel framework that combines visual foundation models (VFM) and offline reinforcement learning (offline RL) to empower embodied visual tracking. We use a pre-trained VFM, such as ``Tracking Anything", to extract semantic segmentation masks with text prompts. We then train a recurrent policy network with offline RL, e.g., Conservative Q-Learning, to learn from the collected demonstrations without online agent-environment interactions. To further improve the robustness and generalization of the policy network, we also introduce a mask re-targeting mechanism and a multi-level data collection strategy. In this way, we can train a robust tracker within an hour on a consumer-level GPU, e.g., Nvidia RTX 3090. Such efficiency is unprecedented for RL-based visual tracking methods. We evaluate our tracker on several high-fidelity environments with challenging situations, such as distraction and occlusion. The results show that our agent outperforms state-of-the-art methods in terms of sample efficiency, robustness to distractors, and generalization to unseen scenarios and targets. We also demonstrate the transferability of the learned tracker from the virtual world to real-world scenarios.