Model brittleness is a key concern when deploying deep learning models in real-world medical settings. A model that has high performance at one institution may suffer a significant decline in performance when tested at other institutions. While pooling datasets from multiple institutions and re-training may provide a straightforward solution, it is often infeasible and may compromise patient privacy. An alternative approach is to fine-tune the model on subsequent institutions after training on the original institution. Notably, this approach degrades model performance at the original institution, a phenomenon known as catastrophic forgetting. In this paper, we develop an approach to address catastrophic forgetting based on elastic weight consolidation combined with modulation of batch normalization statistics under two scenarios: first, for expanding the domain from one imaging system's data to another imaging system's, and second, for expanding the domain from a large multi-institutional dataset to another single institution dataset. We show that our approach outperforms several other state-of-the-art approaches and provide theoretical justification for the efficacy of batch normalization modulation. The results of this study are generally applicable to the deployment of any clinical deep learning model which requires domain expansion.

Sports data has become widely available in the recent past. With the improvement of machine learning techniques, there have been attempts to use sports data to analyze not only the outcome of individual games but also to improve insights and strategies. The outbreak of COVID-19 has interrupted sports leagues globally, giving rise to increasing questions and speculations about the outcome of this season's leagues. What if the season was not interrupted and concluded normally? Which teams would end up winning trophies? Which players would perform the best? Which team would end their season on a high and which teams would fail to keep up with the pressure? We aim to tackle this problem and develop a solution. In this paper, we proposeUCLData, which is a dataset containing detailed information of UEFA Champions League games played over the past six years. We also propose a novel autoencoder based machine learning pipeline that can come up with a story on how the rest of the season will pan out.