We describe the development of a model to detect user-level clinical depression based on a user's temporal social media posts. Our model uses a Depression Symptoms Detection (DSD) classifier, which is trained on the largest existing samples of clinician annotated tweets for clinical depression symptoms. We subsequently use our DSD model to extract clinically relevant features, e.g., depression scores and their consequent temporal patterns, as well as user posting activity patterns, e.g., quantifying their ``no activity'' or ``silence.'' Furthermore, to evaluate the efficacy of these extracted features, we create three kinds of datasets including a test dataset, from two existing well-known benchmark datasets for user-level depression detection. We then provide accuracy measures based on single features, baseline features and feature ablation tests, at several different levels of temporal granularity. The relevant data distributions and clinical depression detection related settings can be exploited to draw a complete picture of the impact of different features across our created datasets. Finally, we show that, in general, only semantic oriented representation models perform well. However, clinical features may enhance overall performance provided that the training and testing distribution is similar, and there is more data in a user's timeline. The consequence is that the predictive capability of depression scores increase significantly while used in a more sensitive clinical depression detection settings.

We focus on exploring various approaches of Zero-Shot Learning (ZSL) and their explainability for a challenging yet important supervised learning task notorious for training data scarcity, i.e. Depression Symptoms Detection (DSD) from text. We start with a comprehensive synthesis of different components of our ZSL modeling and analysis of our ground truth samples and Depression symptom clues curation process with the help of a practicing clinician. We next analyze the accuracy of various state-of-the-art ZSL models and their potential enhancements for our task. Further, we sketch a framework for the use of ZSL for hierarchical text-based explanation mechanism, which we call, Syntax Tree-Guided Semantic Explanation (STEP). Finally, we summarize experiments from which we conclude that we can use ZSL models and achieve reasonable accuracy and explainability, measured by a proposed Explainability Index (EI). This work is, to our knowledge, the first work to exhaustively explore the efficacy of ZSL models for DSD task, both in terms of accuracy and explainability.