This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance on clinical tasks in the target language. Our experiments reveal that the optimal language mix in training data varies significantly across different medical tasks. We find that larger models with carefully calibrated language ratios achieve superior performance on native-language clinical tasks. Furthermore, our results suggest that relying solely on fine-tuning may not be the most effective approach for incorporating new language knowledge into LLMs. Instead, data and computationally intensive pretraining methods may still be necessary to achieve optimal performance in multilingual medical settings. These findings provide valuable guidance for building effective and inclusive medical AI systems for diverse linguistic communities.

This technical report introduces a Named Clinical Entity Recognition Benchmark for evaluating language models in healthcare, addressing the crucial natural language processing (NLP) task of extracting structured information from clinical narratives to support applications like automated coding, clinical trial cohort identification, and clinical decision support. The leaderboard provides a standardized platform for assessing diverse language models, including encoder and decoder architectures, on their ability to identify and classify clinical entities across multiple medical domains. A curated collection of openly available clinical datasets is utilized, encompassing entities such as diseases, symptoms, medications, procedures, and laboratory measurements. Importantly, these entities are standardized according to the Observational Medical Outcomes Partnership (OMOP) Common Data Model, ensuring consistency and interoperability across different healthcare systems and datasets, and a comprehensive evaluation of model performance. Performance of models is primarily assessed using the F1-score, and it is complemented by various assessment modes to provide comprehensive insights into model performance. The report also includes a brief analysis of models evaluated to date, highlighting observed trends and limitations. By establishing this benchmarking framework, the leaderboard aims to promote transparency, facilitate comparative analyses, and drive innovation in clinical entity recognition tasks, addressing the need for robust evaluation methods in healthcare NLP.

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining, instruct fine-tuning, NEFTune, and prompt engineering. We employ these methods on Mistral 7B and Mixtral 8x7B models, leveraging a large-scale clinical pretraining dataset of 50 billion tokens and an instruct fine-tuning dataset of 500 million tokens. Our evaluation across various clinical tasks reveals the impact of each technique. While continuous pretraining beyond 250 billion tokens yields marginal improvements on its own, it establishes a strong foundation for instruct fine-tuning. Notably, NEFTune, designed primarily to enhance generation quality, surprisingly demonstrates additional gains on our benchmark. Complex prompt engineering methods further enhance performance. These findings show the importance of tailoring fine-tuning strategies and exploring innovative techniques to optimize LLM performance in the clinical domain.

Med42-v2 introduces a suite of clinical large language models (LLMs) designed to address the limitations of generic models in healthcare settings. These models are built on Llama3 architecture and fine-tuned using specialized clinical data. They underwent multi-stage preference alignment to effectively respond to natural prompts. While generic models are often preference-aligned to avoid answering clinical queries as a precaution, Med42-v2 is specifically trained to overcome this limitation, enabling its use in clinical settings. Med42-v2 models demonstrate superior performance compared to the original Llama3 models in both 8B and 70B parameter configurations and GPT-4 across various medical benchmarks. These LLMs are developed to understand clinical queries, perform reasoning tasks, and provide valuable assistance in clinical environments. The models are now publicly available at \href{https://huggingface.co/m42-health}{https://huggingface.co/m42-health}.

This paper describes our approach for SemEval-2024 Task 9: BRAINTEASER: A Novel Task Defying Common Sense. The BRAINTEASER task comprises multiple-choice Question Answering designed to evaluate the models' lateral thinking capabilities. It consists of Sentence Puzzle and Word Puzzle subtasks that require models to defy default common-sense associations and exhibit unconventional thinking. We propose a unique strategy to improve the performance of pre-trained language models, notably the Gemini 1.0 Pro Model, in both subtasks. We employ static and dynamic few-shot prompting techniques and introduce a model-generated reasoning strategy that utilizes the LLM's reasoning capabilities to improve performance. Our approach demonstrated significant improvements, showing that it performed better than the baseline models by a considerable margin but fell short of performing as well as the human annotators, thus highlighting the efficacy of the proposed strategies.

This study presents a comprehensive analysis and comparison of two predominant fine-tuning methodologies - full-parameter fine-tuning and parameter-efficient tuning - within the context of medical Large Language Models (LLMs). We developed and refined a series of LLMs, based on the Llama-2 architecture, specifically designed to enhance medical knowledge retrieval, reasoning, and question-answering capabilities. Our experiments systematically evaluate the effectiveness of these tuning strategies across various well-known medical benchmarks. Notably, our medical LLM Med42 showed an accuracy level of 72% on the US Medical Licensing Examination (USMLE) datasets, setting a new standard in performance for openly available medical LLMs. Through this comparative analysis, we aim to identify the most effective and efficient method for fine-tuning LLMs in the medical domain, thereby contributing significantly to the advancement of AI-driven healthcare applications.

Factual consistency is one of the most important requirements when editing high quality documents. It is extremely important for automatic text generation systems like summarization, question answering, dialog modeling, and language modeling. Still, automated factual inconsistency detection is rather under-studied. Existing work has focused on (a) finding fake news keeping a knowledge base in context, or (b) detecting broad contradiction (as part of natural language inference literature). However, there has been no work on detecting and explaining types of factual inconsistencies in text, without any knowledge base in context. In this paper, we leverage existing work in linguistics to formally define five types of factual inconsistencies. Based on this categorization, we contribute a novel dataset, FICLE (Factual Inconsistency CLassification with Explanation), with ~8K samples where each sample consists of two sentences (claim and context) annotated with type and span of inconsistency. When the inconsistency relates to an entity type, it is labeled as well at two levels (coarse and fine-grained). Further, we leverage this dataset to train a pipeline of four neural models to predict inconsistency type with explanations, given a (claim, context) sentence pair. Explanations include inconsistent claim fact triple, inconsistent context span, inconsistent claim component, coarse and fine-grained inconsistent entity types. The proposed system first predicts inconsistent spans from claim and context; and then uses them to predict inconsistency types and inconsistent entity types (when inconsistency is due to entities). We experiment with multiple Transformer-based natural language classification as well as generative models, and find that DeBERTa performs the best. Our proposed methods provide a weighted F1 of ~87% for inconsistency type classification across the five classes.

The evolution of social media platforms have empowered everyone to access information easily. Social media users can easily share information with the rest of the world. This may sometimes encourage spread of fake news, which can result in undesirable consequences. In this work, we train models which can identify health news related to COVID-19 pandemic as real or fake. Our models achieve a high F1-score of 98.64%. Our models achieve second place on the leaderboard, tailing the first position with a very narrow margin 0.05% points.

Detecting and classifying instances of hate in social media text has been a problem of interest in Natural Language Processing in the recent years. Our work leverages state of the art Transformer language models to identify hate speech in a multilingual setting. Capturing the intent of a post or a comment on social media involves careful evaluation of the language style, semantic content and additional pointers such as hashtags and emojis. In this paper, we look at the problem of identifying whether a Twitter post is hateful and offensive or not. We further discriminate the detected toxic content into one of the following three classes: (a) Hate Speech (HATE), (b) Offensive (OFFN) and (c) Profane (PRFN). With a pre-trained multilingual Transformer-based text encoder at the base, we are able to successfully identify and classify hate speech from multiple languages. On the provided testing corpora, we achieve Macro F1 scores of 90.29, 81.87 and 75.40 for English, German and Hindi respectively while performing hate speech detection and of 60.70, 53.28 and 49.74 during fine-grained classification. In our experiments, we show the efficacy of Perspective API features for hate speech classification and the effects of exploiting a multilingual training scheme. A feature selection study is provided to illustrate impacts of specific features upon the architecture's classification head.