Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes of the brain. Alzheimer's disease requires diagnosis by a detailed assessment of MRI scans and neuropsychological tests of the patients. This project compares existing deep learning models in the pursuit of enhancing the accuracy and efficiency of AD diagnosis, specifically focusing on the Convolutional Neural Network, Bayesian Convolutional Neural Network, and the U-net model with the Open Access Series of Imaging Studies brain MRI dataset. Besides, to ensure robustness and reliability in the model evaluations, we address the challenge of imbalance in data. We then perform rigorous evaluation to determine strengths and weaknesses for each model by considering sensitivity, specificity, and computational efficiency. This comparative analysis would shed light on the future role of AI in revolutionizing AD diagnostics but also paved ways for future innovation in medical imaging and the management of neurodegenerative diseases.

Bangla typing is mostly performed using English keyboard and can be highly erroneous due to the presence of compound and similarly pronounced letters. Spelling correction of a misspelled word requires understanding of word typing pattern as well as the context of the word usage. A specialized BERT model named BSpell has been proposed in this paper targeted towards word for word correction in sentence level. BSpell contains an end-to-end trainable CNN sub-model named SemanticNet along with specialized auxiliary loss. This allows BSpell to specialize in highly inflected Bangla vocabulary in the presence of spelling errors. Furthermore, a hybrid pretraining scheme has been proposed for BSpell that combines word level and character level masking. Comparison on two Bangla and one Hindi spelling correction dataset shows the superiority of our proposed approach. BSpell is available as a Bangla spell checking tool via GitHub: https://github.com/Hasiburshanto/Bangla-Spell-Checker