Dynamic effective connectivity networks (dECNs) reveal the changing directed brain activity and the dynamic causal influences among brain regions, which facilitate the identification of individual differences and enhance the understanding of human brain. Although the existing causal discovery methods have shown promising results in effective connectivity network analysis, they often overlook the dynamics of causality, in addition to the incorporation of spatio-temporal information in brain activity data. To address these issues, we propose a deep spatio-temporal fusion architecture, which employs a dynamic causal deep encoder to incorporate spatio-temporal information into dynamic causality modeling, and a dynamic causal deep decoder to verify the discovered causality. The effectiveness of the proposed method is first illustrated with simulated data. Then, experimental results from Philadelphia Neurodevelopmental Cohort (PNC) demonstrate the superiority of the proposed method in inferring dECNs, which reveal the dynamic evolution of directed flow between brain regions. The analysis shows the difference of dECNs between young adults and children. Specifically, the directed brain functional networks transit from fluctuating undifferentiated systems to more stable specialized networks as one grows. This observation provides further evidence on the modularization and adaptation of brain networks during development, leading to higher cognitive abilities observed in young adults.

Objective: fMRI and derived measures such as functional connectivity (FC) have been used to predict brain age, general fluid intelligence, psychiatric disease status, and preclinical neurodegenerative disease. However, it is not always clear that all demographic confounds, such as age, sex, and race, have been removed from fMRI data. Additionally, many fMRI datasets are restricted to authorized researchers, making dissemination of these valuable data sources challenging. Methods: We create a variational autoencoder (VAE)-based model, DemoVAE, to decorrelate fMRI features from demographics and generate high-quality synthetic fMRI data based on user-supplied demographics. We train and validate our model using two large, widely used datasets, the Philadelphia Neurodevelopmental Cohort (PNC) and Bipolar and Schizophrenia Network for Intermediate Phenotypes (BSNIP). Results: We find that DemoVAE recapitulates group differences in fMRI data while capturing the full breadth of individual variations. Significantly, we also find that most clinical and computerized battery fields that are correlated with fMRI data are not correlated with DemoVAE latents. An exception are several fields related to schizophrenia medication and symptom severity. Conclusion: Our model generates fMRI data that captures the full distribution of FC better than traditional VAE or GAN models. We also find that most prediction using fMRI data is dependent on correlation with, and prediction of, demographics. Significance: Our DemoVAE model allows for generation of high quality synthetic data conditioned on subject demographics as well as the removal of the confounding effects of demographics. We identify that FC-based prediction tasks are highly influenced by demographic confounds.

This paper presents LLM4SecHW, a novel framework for hardware debugging that leverages domain specific Large Language Model (LLM). Despite the success of LLMs in automating various software development tasks, their application in the hardware security domain has been limited due to the constraints of commercial LLMs and the scarcity of domain specific data. To address these challenges, we propose a unique approach to compile a dataset of open source hardware design defects and their remediation steps, utilizing version control data. This dataset provides a substantial foundation for training machine learning models for hardware. LLM4SecHW employs fine tuning of medium sized LLMs based on this dataset, enabling the identification and rectification of bugs in hardware designs. This pioneering approach offers a reference workflow for the application of fine tuning domain specific LLMs in other research areas. We evaluate the performance of our proposed system on various open source hardware designs, demonstrating its efficacy in accurately identifying and correcting defects. Our work brings a new perspective on automating the quality control process in hardware design.

Functional connectivity (FC) as derived from fMRI has emerged as a pivotal tool in elucidating the intricacies of various psychiatric disorders and delineating the neural pathways that underpin cognitive and behavioral dynamics inherent to the human brain. While Graph Neural Networks (GNNs) offer a structured approach to represent neuroimaging data, they are limited by their need for a predefined graph structure to depict associations between brain regions, a detail not solely provided by FCs. To bridge this gap, we introduce the Gated Graph Transformer (GGT) framework, designed to predict cognitive metrics based on FCs. Empirical validation on the Philadelphia Neurodevelopmental Cohort (PNC) underscores the superior predictive prowess of our model, further accentuating its potential in identifying pivotal neural connectivities that correlate with human cognitive processes.

Adversarial Examples (AEs) can deceive Deep Neural Networks (DNNs) and have received a lot of attention recently. However, majority of the research on AEs is in the digital domain and the adversarial patches are static, which is very different from many real-world DNN applications such as Traffic Sign Recognition (TSR) systems in autonomous vehicles. In TSR systems, object detectors use DNNs to process streaming video in real time. From the view of object detectors, the traffic sign`s position and quality of the video are continuously changing, rendering the digital AEs ineffective in the physical world. In this paper, we propose a systematic pipeline to generate robust physical AEs against real-world object detectors. Robustness is achieved in three ways. First, we simulate the in-vehicle cameras by extending the distribution of image transformations with the blur transformation and the resolution transformation. Second, we design the single and multiple bounding boxes filters to improve the efficiency of the perturbation training. Third, we consider four representative attack vectors, namely Hiding Attack, Appearance Attack, Non-Target Attack and Target Attack. We perform a comprehensive set of experiments under a variety of environmental conditions, and considering illuminations in sunny and cloudy weather as well as at night. The experimental results show that the physical AEs generated from our pipeline are effective and robust when attacking the YOLO v5 based TSR system. The attacks have good transferability and can deceive other state-of-the-art object detectors. We launched HA and NTA on a brand-new 2021 model vehicle. Both attacks are successful in fooling the TSR system, which could be a life-threatening case for autonomous vehicles. Finally, we discuss three defense mechanisms based on image preprocessing, AEs detection, and model enhancing.

Engineering a top-notch deep learning model is an expensive procedure that involves collecting data, hiring human resources with expertise in machine learning, and providing high computational resources. For that reason, deep learning models are considered as valuable Intellectual Properties (IPs) of the model vendors. To ensure reliable commercialization of deep learning models, it is crucial to develop techniques to protect model vendors against IP infringements. One of such techniques that recently has shown great promise is digital watermarking. However, current watermarking approaches can embed very limited amount of information and are vulnerable against watermark removal attacks. In this paper, we present GradSigns, a novel watermarking framework for deep neural networks (DNNs). GradSigns embeds the owner's signature into the gradient of the cross-entropy cost function with respect to inputs to the model. Our approach has a negligible impact on the performance of the protected model and it allows model vendors to remotely verify the watermark through prediction APIs. We evaluate GradSigns on DNNs trained for different image classification tasks using CIFAR-10, SVHN, and YTF datasets. Experimental results show that GradSigns is robust against all known counter-watermark attacks and can embed a large amount of information into DNNs.

Resting-state functional magnetic resonance imaging (rs-fMRI)-derived functional connectivity patterns have been extensively utilized to delineate global functional organization of the human brain in health, development, and neuropsychiatric disorders. In this paper, we investigate how functional connectivity in males and females differs in an age prediction framework. We first estimate functional connectivity between regions-of-interest (ROIs) using distance correlation instead of Pearson's correlation. Distance correlation, as a multivariate statistical method, explores spatial relations of voxel-wise time courses within individual ROIs and measures both linear and nonlinear dependence, capturing more complex information of between-ROI interactions. Then, a novel non-convex multi-task learning (NC-MTL) model is proposed to study age-related gender differences in functional connectivity, where age prediction for each gender group is viewed as one task. Specifically, in the proposed NC-MTL model, we introduce a composite regularizer with a combination of non-convex $\ell_{2,1-2}$ and $\ell_{1-2}$ regularization terms for selecting both common and task-specific features. Finally, we validate the proposed NC-MTL model along with distance correlation based functional connectivity on rs-fMRI of the Philadelphia Neurodevelopmental Cohort for predicting ages of both genders. The experimental results demonstrate that the proposed NC-MTL model outperforms other competing MTL models in age prediction, as well as characterizing developmental gender differences in functional connectivity patterns.