Pitts, Walter
Investigations on Synaptic Transmission
Pitts, Walter
' This work was done in collaboration with Drs. But it is attenuated because the electrode computes a weighted average over a volume of a function whose own average is zero. To this external medium, the nerve appears to produce, absorb, then produce current when a spike passes; from this probe's standpoint of view, the impulse is a source, followed by sink, followed by source. Their algebraic sum in time is zero, unless the impulse stops either at the electrode or short of it. In the former case, the preceding source is averaged with the initial part of the sink, but the stationary decaying sink is recorded as a large negative potential with respect to a remote electrode.