Segment Anything Model (SAM) demonstrates powerful zero-shot capabilities; however, its accuracy and robustness significantly decrease when applied to medical image segmentation. Existing methods address this issue through modality fusion, integrating textual and image information to provide more detailed priors. In this study, we argue that the granularity of text and the domain gap affect the accuracy of the priors. Furthermore, the discrepancy between high-level abstract semantics and pixel-level boundary details in images can introduce noise into the fusion process. To address this, we propose Prior-Guided SAM (PG-SAM), which employs a fine-grained modality prior aligner to leverage specialized medical knowledge for better modality alignment. The core of our method lies in efficiently addressing the domain gap with fine-grained text from a medical LLM. Meanwhile, it also enhances the priors' quality after modality alignment, ensuring more accurate segmentation. In addition, our decoder enhances the model's expressive capabilities through multi-level feature fusion and iterative mask optimizer operations, supporting unprompted learning. We also propose a unified pipeline that effectively supplies high-quality semantic information to SAM. Extensive experiments on the Synapse dataset demonstrate that the proposed PG-SAM achieves state-of-the-art performance. Our anonymous code is released at https://github.com/logan-0623/PG-SAM.

Video diffusion models (VDMs) facilitate the generation of high-quality videos, with current research predominantly concentrated on scaling efforts during training through improvements in data quality, computational resources, and model complexity. However, inference-time scaling has received less attention, with most approaches restricting models to a single generation attempt. Recent studies have uncovered the existence of "golden noises" that can enhance video quality during generation. Building on this, we find that guiding the scaling inference-time search of VDMs to identify better noise candidates not only evaluates the quality of the frames generated in the current step but also preserves the high-level object features by referencing the anchor frame from previous multi-chunks, thereby delivering long-term value. Our analysis reveals that diffusion models inherently possess flexible adjustments of computation by varying denoising steps, and even a one-step denoising approach, when guided by a reward signal, yields significant long-term benefits. Based on the observation, we proposeScalingNoise, a plug-and-play inference-time search strategy that identifies golden initial noises for the diffusion sampling process to improve global content consistency and visual diversity. Specifically, we perform one-step denoising to convert initial noises into a clip and subsequently evaluate its long-term value, leveraging a reward model anchored by previously generated content. Moreover, to preserve diversity, we sample candidates from a tilted noise distribution that up-weights promising noises. In this way, ScalingNoise significantly reduces noise-induced errors, ensuring more coherent and spatiotemporally consistent video generation. Extensive experiments on benchmark datasets demonstrate that the proposed ScalingNoise effectively improves long video generation.

Land cover analysis using hyperspectral images (HSI) remains an open problem due to their low spatial resolution and complex spectral information. Recent studies are primarily dedicated to designing Transformer-based architectures for spatial-spectral long-range dependencies modeling, which is computationally expensive with quadratic complexity. Selective structured state space model (Mamba), which is efficient for modeling long-range dependencies with linear complexity, has recently shown promising progress. However, its potential in hyperspectral image processing that requires handling numerous spectral bands has not yet been explored. In this paper, we innovatively propose S$^2$Mamba, a spatial-spectral state space model for hyperspectral image classification, to excavate spatial-spectral contextual features, resulting in more efficient and accurate land cover analysis. In S$^2$Mamba, two selective structured state space models through different dimensions are designed for feature extraction, one for spatial, and the other for spectral, along with a spatial-spectral mixture gate for optimal fusion. More specifically, S$^2$Mamba first captures spatial contextual relations by interacting each pixel with its adjacent through a Patch Cross Scanning module and then explores semantic information from continuous spectral bands through a Bi-directional Spectral Scanning module. Considering the distinct expertise of the two attributes in homogenous and complicated texture scenes, we realize the Spatial-spectral Mixture Gate by a group of learnable matrices, allowing for the adaptive incorporation of representations learned across different dimensions. Extensive experiments conducted on HSI classification benchmarks demonstrate the superiority and prospect of S$^2$Mamba. The code will be available at: https://github.com/PURE-melo/S2Mamba.