Existing Large Multimodal Models (LMMs) generally focus on only a few regions and languages. As LMMs continue to improve, it is increasingly important to ensure they understand cultural contexts, respect local sensitivities, and support low-resource languages, all while effectively integrating corresponding visual cues. In pursuit of culturally diverse global multimodal models, our proposed All Languages Matter Benchmark (ALM-bench) represents the largest and most comprehensive effort to date for evaluating LMMs across 100 languages. ALM-bench challenges existing models by testing their ability to understand and reason about culturally diverse images paired with text in various languages, including many low-resource languages traditionally underrepresented in LMM research. The benchmark offers a robust and nuanced evaluation framework featuring various question formats, including true/false, multiple choice, and open-ended questions, which are further divided into short and long-answer categories. ALM-bench design ensures a comprehensive assessment of a model's ability to handle varied levels of difficulty in visual and linguistic reasoning. To capture the rich tapestry of global cultures, ALM-bench carefully curates content from 13 distinct cultural aspects, ranging from traditions and rituals to famous personalities and celebrations. Through this, ALM-bench not only provides a rigorous testing ground for state-of-the-art open and closed-source LMMs but also highlights the importance of cultural and linguistic inclusivity, encouraging the development of models that can serve diverse global populations effectively. Our benchmark is publicly available.

Survival analysis plays a crucial role in estimating the likelihood of future events for patients by modeling time-to-event data, particularly in healthcare settings where predictions about outcomes such as death and disease recurrence are essential. However, this analysis poses challenges due to the presence of censored data, where time-to-event information is missing for certain data points. Yet, censored data can offer valuable insights, provided we appropriately incorporate the censoring time during modeling. In this paper, we propose SurvCORN, a novel method utilizing conditional ordinal ranking networks to predict survival curves directly. Additionally, we introduce SurvMAE, a metric designed to evaluate the accuracy of model predictions in estimating time-to-event outcomes. Through empirical evaluation on two real-world cancer datasets, we demonstrate SurvCORN's ability to maintain accurate ordering between patient outcomes while improving individual time-to-event predictions. Our contributions extend recent advancements in ordinal regression to survival analysis, offering valuable insights into accurate prognosis in healthcare settings.

Predicting the likelihood of survival is of paramount importance for individuals diagnosed with cancer as it provides invaluable information regarding prognosis at an early stage. This knowledge enables the formulation of effective treatment plans that lead to improved patient outcomes. In the past few years, deep learning models have provided a feasible solution for assessing medical images, electronic health records, and genomic data to estimate cancer risk scores. However, these models often fall short of their potential because they struggle to learn regression-aware feature representations. In this study, we propose Survival Rank-N Contrast (SurvRNC) method, which introduces a loss function as a regularizer to obtain an ordered representation based on the survival times. This function can handle censored data and can be incorporated into any survival model to ensure that the learned representation is ordinal. The model was extensively evaluated on a HEad \& NeCK TumOR (HECKTOR) segmentation and the outcome-prediction task dataset. We demonstrate that using the SurvRNC method for training can achieve higher performance on different deep survival models. Additionally, it outperforms state-of-the-art methods by 3.6% on the concordance index. The code is publicly available on https://github.com/numanai/SurvRNC

Deep learning (DL) models have been advancing automatic medical image analysis on various modalities, including echocardiography, by offering a comprehensive end-to-end training pipeline. This approach enables DL models to regress ejection fraction (EF) directly from 2D+time echocardiograms, resulting in superior performance. However, the end-to-end training pipeline makes the learned representations less explainable. The representations may also fail to capture the continuous relation among echocardiogram clips, indicating the existence of spurious correlations, which can negatively affect the generalization. To mitigate this issue, we propose CoReEcho, a novel training framework emphasizing continuous representations tailored for direct EF regression. Our extensive experiments demonstrate that CoReEcho: 1) outperforms the current state-of-the-art (SOTA) on the largest echocardiography dataset (EchoNet-Dynamic) with MAE of 3.90 & R2 of 82.44, and 2) provides robust and generalizable features that transfer more effectively in related downstream tasks.