Segment Anything Model (SAM) demonstrates powerful zero-shot capabilities; however, its accuracy and robustness significantly decrease when applied to medical image segmentation. Existing methods address this issue through modality fusion, integrating textual and image information to provide more detailed priors. In this study, we argue that the granularity of text and the domain gap affect the accuracy of the priors. Furthermore, the discrepancy between high-level abstract semantics and pixel-level boundary details in images can introduce noise into the fusion process. To address this, we propose Prior-Guided SAM (PG-SAM), which employs a fine-grained modality prior aligner to leverage specialized medical knowledge for better modality alignment. The core of our method lies in efficiently addressing the domain gap with fine-grained text from a medical LLM. Meanwhile, it also enhances the priors' quality after modality alignment, ensuring more accurate segmentation. In addition, our decoder enhances the model's expressive capabilities through multi-level feature fusion and iterative mask optimizer operations, supporting unprompted learning. We also propose a unified pipeline that effectively supplies high-quality semantic information to SAM. Extensive experiments on the Synapse dataset demonstrate that the proposed PG-SAM achieves state-of-the-art performance. Our anonymous code is released at https://github.com/logan-0623/PG-SAM.

Recent advancements in multi-modal artificial intelligence (AI) have revolutionized the fields of stock market forecasting and heart rate monitoring. Utilizing diverse data sources can substantially improve prediction accuracy. Nonetheless, additional data may not always align with the original dataset. Interpolation methods are commonly utilized for handling missing values in modal data, though they may exhibit limitations in the context of sparse information. Addressing this challenge, we propose a Modality Completion Deep Belief Network-Based Model (MC-DBN). This approach utilizes implicit features of complete data to compensate for gaps between itself and additional incomplete data. It ensures that the enhanced multi-modal data closely aligns with the dynamic nature of the real world to enhance the effectiveness of the model. We conduct evaluations of the MC-DBN model in two datasets from the stock market forecasting and heart rate monitoring domains. Comprehensive experiments showcase the model's capacity to bridge the semantic divide present in multi-modal data, subsequently enhancing its performance. The source code is available at: https://github.com/logan-0623/DBN-generate