The development of social media platforms has revolutionized the speed and manner in which information is disseminated, leading to both beneficial and detrimental effects on society. While these platforms facilitate rapid communication, they also accelerate the spread of rumors and extremist speech, impacting public perception and behavior significantly. This issue is particularly pronounced during election periods, where the influence of social media on election outcomes has become a matter of global concern. With the unprecedented number of elections in 2024, against this backdrop, the election ecosystem has encountered unprecedented challenges. This study addresses the urgent need for effective rumor detection on social media by proposing a novel method that combines semantic analysis with graph neural networks. We have meticulously collected a dataset from PolitiFact and Twitter, focusing on politically relevant rumors. Our approach involves semantic analysis using a fine-tuned BERT model to vectorize text content and construct a directed graph where tweets and comments are nodes, and interactions are edges. The core of our method is a graph neural network, SAGEWithEdgeAttention, which extends the GraphSAGE model by incorporating first-order differences as edge attributes and applying an attention mechanism to enhance feature aggregation. This innovative approach allows for the fine-grained analysis of the complex social network structure, improving rumor detection accuracy. The study concludes that our method significantly outperforms traditional content analysis and time-based models, offering a theoretically sound and practically efficient solution.

Data classification techniques partition the data or feature space into smaller sub-spaces, each corresponding to a specific class. To classify into subspaces, physical features e.g., distance and distributions are utilized. This approach is challenging for the characterization of complex patterns that are embedded in the dataset. However, complex networks remain a powerful technique for capturing internal relationships and class structures, enabling High-Level Classification. Although several complex network-based classification techniques have been proposed, high-level classification by leveraging pattern formation to classify data has not been utilized. In this work, we present two network-based classification techniques utilizing unique measures derived from the Minimum Spanning Tree and Single Source Shortest Path. These network measures are evaluated from the data patterns represented by the inherent network constructed from each class. We have applied our proposed techniques to several data classification scenarios including synthetic and real-world datasets. Compared to the existing classic high-level and machine-learning classification techniques, we have observed promising numerical results for our proposed approaches. Furthermore, the proposed models demonstrate the following distinguished features in comparison to the previous high-level classification techniques: (1) A single network measure is introduced to characterize the data pattern, eliminating the need to determine weight parameters among network measures. Therefore, the model is largely simplified, while obtaining better classification results. (2) The metrics proposed are sensitive and used for classification with competitive results.

The integration of generative AI (GenAI) and large language models (LLMs) in healthcare presents both unprecedented opportunities and challenges, necessitating innovative regulatory approaches. GenAI and LLMs offer broad applications, from automating clinical workflows to personalizing diagnostics. However, the non-deterministic outputs, broad functionalities and complex integration of GenAI and LLMs challenge existing medical device regulatory frameworks, including the total product life cycle (TPLC) approach. Here we discuss the constraints of the TPLC approach to GenAI and LLM-based medical device regulation, and advocate for global collaboration in regulatory science research. This serves as the foundation for developing innovative approaches including adaptive policies and regulatory sandboxes, to test and refine governance in real-world settings. International harmonization, as seen with the International Medical Device Regulators Forum, is essential to manage implications of LLM on global health, including risks of widening health inequities driven by inherent model biases. By engaging multidisciplinary expertise, prioritizing iterative, data-driven approaches, and focusing on the needs of diverse populations, global regulatory science research enables the responsible and equitable advancement of LLM innovations in healthcare.