Oral cancer is a global health challenge. It is treatable if detected early, but it is often fatal in late stages. There is a shift from the invasive and time-consuming tissue sampling and histological examination, toward non-invasive brush biopsies and cytological examination. Reliable computer-assisted methods are essential for cost-effective and accurate cytological analysis, but the lack of detailed cell-level annotations impairs model effectiveness. This study aims to improve AI-based oral cancer detection using multimodal imaging and deep fusion. We combine brightfield and fluorescence whole slide microscopy imaging to analyze Papanicolaou-stained liquid-based cytology slides of brush biopsies collected from both healthy and cancer patients. Due to limited cytological annotations, we utilize a weakly supervised deep learning approach using only patient-level labels. We evaluate various multimodal fusion strategies, including early, late, and three recent intermediate fusion methods. Our results show: (i) fluorescence imaging of Papanicolaou-stained samples provides substantial diagnostic information; (ii) multimodal fusion enhances classification and cancer detection accuracy over single-modality methods. Intermediate fusion is the leading method among the studied approaches. Specifically, the Co-Attention Fusion Network (CAFNet) model excels with an F1 score of 83.34% and accuracy of 91.79%, surpassing human performance on the task. Additional tests highlight the need for precise image registration to optimize multimodal analysis benefits. This study advances cytopathology by combining deep learning and multimodal imaging to enhance early, non-invasive detection of oral cancer, improving diagnostic accuracy and streamlining clinical workflows. The developed pipeline is also applicable in other cytological settings. Our codes and dataset are available online for further research.

Bokeh effect is an optical phenomenon that offers a pleasant visual experience, typically generated by high-end cameras with wide aperture lenses. The task of bokeh effect transformation aims to produce a desired effect in one set of lenses and apertures based on another combination. Current models are limited in their ability to render a specific set of bokeh effects, primarily transformations from sharp to blur. In this paper, we propose a novel universal method for embedding lens metadata into the model and introducing a loss calculation method using alpha masks from the newly released Bokeh Effect Transformation Dataset(BETD) [3]. Based on the above techniques, we propose the BokehOrNot model, which is capable of producing both blur-to-sharp and sharp-to-blur bokeh effect with various combinations of lenses and aperture sizes. Our proposed model outperforms current leading bokeh rendering and image restoration models and renders visually natural bokeh effects. Our code is available at: https://github.com/indicator0/bokehornot.

Burst super-resolution (SR) provides a possibility of restoring rich details from low-quality images. However, since low-resolution (LR) images in practical applications have multiple complicated and unknown degradations, existing non-blind (e.g., bicubic) designed networks usually lead to a severe performance drop in recovering high-resolution (HR) images. Moreover, handling multiple misaligned noisy raw inputs is also challenging. In this paper, we address the problem of reconstructing HR images from raw burst sequences acquired from modern handheld devices. The central idea is a kernel-guided strategy which can solve the burst SR with two steps: kernel modeling and HR restoring. The former estimates burst kernels from raw inputs, while the latter predicts the super-resolved image based on the estimated kernels. Furthermore, we introduce a kernel-aware deformable alignment module which can effectively align the raw images with consideration of the blurry priors. Extensive experiments on synthetic and real-world datasets demonstrate that the proposed method can perform favorable state-of-the-art performance in the burst SR problem.