Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one of the earliest signs of cognitive decline, which can be used to discriminate AD patients from normal control individuals. Patient-interviewer dialogues may be used to detect such impairments, but they are often mixed with ambiguous, noisy, and irrelevant information, making the AD detection task difficult. Moreover, the limited availability of AD speech samples and variability in their speech styles pose significant challenges in developing robust speech-based AD detection models. To address these challenges, we propose DECT, a novel speech-based domain-specific approach leveraging large language models (LLMs) for fine-grained linguistic analysis and label-switched label-preserved data generation. Our study presents four novelties: We harness the summarizing capabilities of LLMs to identify and distill key Cognitive-Linguistic information from noisy speech transcripts, effectively filtering irrelevant information. We leverage the inherent linguistic knowledge of LLMs to extract linguistic markers from unstructured and heterogeneous audio transcripts. We exploit the compositional ability of LLMs to generate AD speech transcripts consisting of diverse linguistic patterns to overcome the speech data scarcity challenge and enhance the robustness of AD detection models. We use the augmented AD textual speech transcript dataset and a more fine-grained representation of AD textual speech transcript data to fine-tune the AD detection model. The results have shown that DECT demonstrates superior model performance with an 11% improvement in AD detection accuracy on the datasets from DementiaBank compared to the baselines.

The key issue of few-shot learning is learning to generalize. In this paper, we propose a large margin principle to improve the generalization capacity of metric based methods for few-shot learning. To realize it, we develop a unified framework to learn a more discriminative metric space by augmenting the softmax classification loss function with a large margin distance loss function for training. Extensive experiments on two state-of-the-art few-shot learning models, graph neural networks and prototypical networks, show that our method can improve the performance of existing models substantially with very little computational overhead, demonstrating the effectiveness of the large margin principle and the potential of our method.

Many countries are suffering from severe air pollution. Understanding how different air pollutants accumulate and propagate is critical to making relevant public policies. In this paper, we use urban big data (air quality data and meteorological data) to identify the \emph{spatiotemporal (ST) causal pathways} for air pollutants. This problem is challenging because: (1) there are numerous noisy and low-pollution periods in the raw air quality data, which may lead to unreliable causality analysis, (2) for large-scale data in the ST space, the computational complexity of constructing a causal structure is very high, and (3) the \emph{ST causal pathways} are complex due to the interactions of multiple pollutants and the influence of environmental factors. Therefore, we present \emph{p-Causality}, a novel pattern-aided causality analysis approach that combines the strengths of \emph{pattern mining} and \emph{Bayesian learning} to efficiently and faithfully identify the \emph{ST causal pathways}. First, \emph{Pattern mining} helps suppress the noise by capturing frequent evolving patterns (FEPs) of each monitoring sensor, and greatly reduce the complexity by selecting the pattern-matched sensors as "causers". Then, \emph{Bayesian learning} carefully encodes the local and ST causal relations with a Gaussian Bayesian network (GBN)-based graphical model, which also integrates environmental influences to minimize biases in the final results. We evaluate our approach with three real-world data sets containing 982 air quality sensors, in three regions of China from 01-Jun-2013 to 19-Dec-2015. Results show that our approach outperforms the traditional causal structure learning methods in time efficiency, inference accuracy and interpretability.

We address an important problem in sequence-to-sequence (Seq2Seq) learning referred to as copying, in which certain segments in the input sequence are selectively replicated in the output sequence. A similar phenomenon is observable in human language communication. For example, humans tend to repeat entity names or even long phrases in conversation. The challenge with regard to copying in Seq2Seq is that new machinery is needed to decide when to perform the operation. In this paper, we incorporate copying into neural network-based Seq2Seq learning and propose a new model called CopyNet with encoder-decoder structure. CopyNet can nicely integrate the regular way of word generation in the decoder with the new copying mechanism which can choose sub-sequences in the input sequence and put them at proper places in the output sequence. Our empirical study on both synthetic data sets and real world data sets demonstrates the efficacy of CopyNet. For example, CopyNet can outperform regular RNN-based model with remarkable margins on text summarization tasks.

Replicated Softmax model, a well-known undirected topic model, is powerful in extracting semantic representations of documents. Traditional learning strategies such as Contrastive Divergence are very inefficient. This paper provides a novel estimator to speed up the learning based on Noise Contrastive Estimate, extended for documents of variant lengths and weighted inputs. Experiments on two benchmarks show that the new estimator achieves great learning efficiency and high accuracy on document retrieval and classification.