A CAD command sequence is a typical parametric design paradigm in 3D CAD systems where a model is constructed by overlaying 2D sketches with operations such as extrusion, revolution, and Boolean operations. Although there is growing academic interest in the automatic generation of command sequences, existing methods and datasets only support operations such as 2D sketching, extrusion,and Boolean operations. This limitation makes it challenging to represent more complex geometries. In this paper, we present a reinforcement learning (RL) training environment (gym) built on a CAD geometric engine. Given an input boundary representation (B-Rep) geometry, the policy network in the RL algorithm generates an action. This action, along with previously generated actions, is processed within the gym to produce the corresponding CAD geometry, which is then fed back into the policy network. The rewards, determined by the difference between the generated and target geometries within the gym, are used to update the RL network. Our method supports operations beyond sketches, Boolean, and extrusion, including revolution operations. With this training gym, we achieve state-of-the-art (SOTA) quality in generating command sequences from B-Rep geometries. In addition, our method can significantly improve the efficiency of command sequence generation by a factor of 39X compared with the previous training gym.

In tackling the challenges of large language model (LLM) performance for Text-to-SQL tasks, we introduce CHASE-SQL, a new framework that employs innovative strategies, using test-time compute in multi-agent modeling to improve candidate generation and selection. CHASE-SQL leverages LLMs' intrinsic knowledge to generate diverse and high-quality SQL candidates using different LLM generators with: (1) a divide-and-conquer method that decomposes complex queries into manageable sub-queries in a single LLM call; (2) chain-of-thought reasoning based on query execution plans, reflecting the steps a database engine takes during execution; and (3) a unique instance-aware synthetic example generation technique, which offers specific few-shot demonstrations tailored to test questions.To identify the best candidate, a selection agent is employed to rank the candidates through pairwise comparisons with a fine-tuned binary-candidates selection LLM. This selection approach has been demonstrated to be more robust over alternatives. The proposed generators-selector framework not only enhances the quality and diversity of SQL queries but also outperforms previous methods. Overall, our proposed CHASE-SQL achieves the state-of-the-art execution accuracy of 73.0% and 73.01% on the test set and development set of the notable BIRD Text-to-SQL dataset benchmark, rendering CHASE-SQL the top submission of the leaderboard (at the time of paper submission).

The integration of artificial intelligence (AI) with radiology has marked a transformative era in medical diagnostics. Vision foundation models have been adopted to enhance radiologic imaging analysis. However, the distinct complexities of radiological imaging, including the interpretation of 2D and 3D radiological data, pose unique challenges that existing models, trained on general non-medical images, fail to address adequately. To bridge this gap and capitalize on the diagnostic precision required in medical imaging, we introduce RadCLIP: a pioneering cross-modal foundational model that harnesses Contrastive Language-Image Pre-training (CLIP) to refine radiologic image analysis. RadCLIP incorporates a novel 3D slice pooling mechanism tailored for volumetric image analysis and is trained using a comprehensive and diverse dataset of radiologic image-text pairs. Our evaluations demonstrate that RadCLIP effectively aligns radiological images with their corresponding textual annotations, and in the meantime, offers a robust vision backbone for radiologic imagery with significant promise.

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and enhancing disease diagnosis. The development of such a technique hinges on the efficient fusion of heterogeneous multimodal features, which initially reside within distinct representation spaces. Naively fusing the multimodal features does not adequately capture the complementary information and could even produce redundancy. In this work, we present a novel joint self-supervised and supervised contrastive learning method to learn the robust latent feature representation from multimodal MRI data, allowing the projection of heterogeneous features into a shared common space, and thereby amalgamating both complementary and analogous information across various modalities and among similar subjects. We performed a comparative analysis between our proposed method and alternative deep multimodal learning approaches. Through extensive experiments on two independent datasets, the results demonstrated that our method is significantly superior to several other deep multimodal learning methods in predicting abnormal neurodevelopment. Our method has the capability to facilitate computer-aided diagnosis within clinical practice, harnessing the power of multimodal data.

The computer-aided disease diagnosis from radiomic data is important in many medical applications. However, developing such a technique relies on annotating radiological images, which is a time-consuming, labor-intensive, and expensive process. In this work, we present the first novel collaborative self-supervised learning method to solve the challenge of insufficient labeled radiomic data, whose characteristics are different from text and image data. To achieve this, we present two collaborative pretext tasks that explore the latent pathological or biological relationships between regions of interest and the similarity and dissimilarity information between subjects. Our method collaboratively learns the robust latent feature representations from radiomic data in a self-supervised manner to reduce human annotation efforts, which benefits the disease diagnosis. We compared our proposed method with other state-of-the-art self-supervised learning methods on a simulation study and two independent datasets. Extensive experimental results demonstrated that our method outperforms other self-supervised learning methods on both classification and regression tasks. With further refinement, our method shows the potential advantage in automatic disease diagnosis with large-scale unlabeled data available.

Heat demand prediction is a prominent research topic in the area of intelligent energy networks. It has been well recognized that periodicity is one of the important characteristics of heat demand. Seasonal-trend decomposition based on LOESS (STL) algorithm can analyze the periodicity of a heat demand series, and decompose the series into seasonal and trend components. Then, predicting the seasonal and trend components respectively, and combining their predictions together as the heat demand prediction is a possible way to predict heat demand. In this paper, STL-ENN-ARIMA (SEA), a combined model, was proposed based on the combination of the Elman neural network (ENN) and the autoregressive integrated moving average (ARIMA) model, which are commonly applied to heat demand prediction. ENN and ARIMA are used to predict seasonal and trend components, respectively. Experimental results demonstrate that the proposed SEA model has a promising performance.