The increasing demand for processing large volumes of data for machine learning models has pushed data bandwidth requirements beyond the capability of traditional von Neumann architecture. In-memory computing (IMC) has recently emerged as a promising solution to address this gap by enabling distributed data storage and processing at the micro-architectural level, significantly reducing both latency and energy. In this paper, we present the IMPACT: InMemory ComPuting Architecture Based on Y-FlAsh Technology for Coalesced Tsetlin Machine Inference, underpinned on a cutting-edge memory device, Y-Flash, fabricated on a 180 nm CMOS process. Y-Flash devices have recently been demonstrated for digital and analog memory applications, offering high yield, non-volatility, and low power consumption. The IMPACT leverages the Y-Flash array to implement the inference of a novel machine learning algorithm: coalesced Tsetlin machine (CoTM) based on propositional logic. CoTM utilizes Tsetlin automata (TA) to create Boolean feature selections stochastically across parallel clauses. The IMPACT is organized into two computational crossbars for storing the TA and weights. Through validation on the MNIST dataset, IMPACT achieved 96.3% accuracy. The IMPACT demonstrated improvements in energy efficiency, e.g., 2.23X over CNN-based ReRAM, 2.46X over Neuromorphic using NOR-Flash, and 2.06X over DNN-based PCM, suited for modern ML inference applications.

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important. This paper introduces ClaPIM, a scalable DNA sequence classification architecture based on the emerging concept of hybrid in-crossbar and near-crossbar memristive processing-in-memory (PIM). We enable efficient and high-quality classification by uniting the filter and search stages within a single algorithm. Specifically, we propose a custom filtering technique that drastically narrows the search space and a search approach that facilitates approximate string matching through a distance function. ClaPIM is the first PIM architecture for scalable approximate string matching that benefits from the high density of memristive crossbar arrays and the massive computational parallelism of PIM. Compared with Kraken2, a state-of-the-art software classifier, ClaPIM provides significantly higher classification quality (up to 20x improvement in F1 score) and also demonstrates a 1.8x throughput improvement. Compared with EDAM, a recently-proposed SRAM-based accelerator that is restricted to small datasets, we observe both a 30.4x improvement in normalized throughput per area and a 7% increase in classification precision.