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Collaborating Authors

 Kapicioglu, Berk


Relation-weighted Link Prediction for Disease Gene Identification

arXiv.org Artificial Intelligence

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this problem, propose a novel machine learning method that identifies disease genes on such graphs by leveraging recent advances in network biology and graph representation learning, study the effects of various relation types on prediction performance, and empirically demonstrate that our algorithms outperform its closest state-of-the-art competitor in disease gene identification by 24.1%. We also show that we achieve higher precision than Open Targets, the leading initiative for target identification, with respect to predicting drug targets in clinical trials for Parkinson's disease.


Chess2vec: Learning Vector Representations for Chess

arXiv.org Artificial Intelligence

We conduct the first study of its kind to generate and evaluate vector representations for chess pieces. In particular, we uncover the latent structure of chess pieces and moves, as well as predict chess moves from chess positions. We share preliminary results which anticipate our ongoing work on a neural network architecture that learns these embeddings directly from supervised feedback. The fundamental challenge for machine learning based chess programs is to learn the mapping between chess positions and optimal moves [5, 3, 7]. A chess position is a description of where pieces are located on the chessboard. In learning, chess positions are typically represented as bitboard representations [1]. A bitboard is a 8 8 binary matrix, same dimensions as the chessboard, and each bitboard is associated with a particular piece type (e.g.


Combining Spatial and Telemetric Features for Learning Animal Movement Models

arXiv.org Machine Learning

We introduce a new graphical model for tracking radio-tagged animals and learning their movement patterns. The model provides a principled way to combine radio telemetry data with an arbitrary set of userdefined, spatial features. We describe an efficient stochastic gradient algorithm for fitting model parameters to data and demonstrate its effectiveness via asymptotic analysis and synthetic experiments. We also apply our model to real datasets, and show that it outperforms the most popular radio telemetry software package used in ecology. We conclude that integration of different data sources under a single statistical framework, coupled with appropriate parameter and state estimation procedures, produces both accurate location estimates and an interpretable statistical model of animal movement.