Prior to the deep learning era, shape was commonly used to describe the objects. Nowadays, state-of-the-art (SOTA) algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from numerous shape-related publications in premier vision conferences as well as the growing popularity of ShapeNet (about 51,300 models) and Princeton ModelNet (127,915 models). For the medical domain, we present a large collection of anatomical shapes (e.g., bones, organs, vessels) and 3D models of surgical instrument, called MedShapeNet, created to facilitate the translation of data-driven vision algorithms to medical applications and to adapt SOTA vision algorithms to medical problems. As a unique feature, we directly model the majority of shapes on the imaging data of real patients. As of today, MedShapeNet includes 23 dataset with more than 100,000 shapes that are paired with annotations (ground truth). Our data is freely accessible via a web interface and a Python application programming interface (API) and can be used for discriminative, reconstructive, and variational benchmarks as well as various applications in virtual, augmented, or mixed reality, and 3D printing. Exemplary, we present use cases in the fields of classification of brain tumors, facial and skull reconstructions, multi-class anatomy completion, education, and 3D printing. In future, we will extend the data and improve the interfaces. The project pages are: https://medshapenet.ikim.nrw/ and https://github.com/Jianningli/medshapenet-feedback

Derivative-free optimization algorithms play an important role in scientific and engineering design optimization problems, especially when derivative information is not accessible. In this paper, we study the framework of classification-based derivative-free optimization algorithms. By introducing a concept called hypothesis-target shattering rate, we revisit the computational complexity upper bound of this type of algorithms. Inspired by the revisited upper bound, we propose an algorithm named "RACE-CARS", which adds a random region-shrinking step compared with "SRACOS" (Hu et al., 2017).. We further establish a theorem showing the acceleration of region-shrinking. Experiments on the synthetic functions as well as black-box tuning for language-model-as-a-service demonstrate empirically the efficiency of "RACE-CARS". An ablation experiment on the introduced hyperparameters is also conducted, revealing the mechanism of "RACE-CARS" and putting forward an empirical hyperparameter-tuning guidance.

The accurate diagnosis on pathological subtypes for lung cancer is of significant importance for the follow-up treatments and prognosis managements. In this paper, we propose self-generating hybrid feature network (SGHF-Net) for accurately classifying lung cancer subtypes on computed tomography (CT) images. Inspired by studies stating that cross-scale associations exist in the image patterns between the same case's CT images and its pathological images, we innovatively developed a pathological feature synthetic module (PFSM), which quantitatively maps cross-modality associations through deep neural networks, to derive the "gold standard" information contained in the corresponding pathological images from CT images. Additionally, we designed a radiological feature extraction module (RFEM) to directly acquire CT image information and integrated it with the pathological priors under an effective feature fusion framework, enabling the entire classification model to generate more indicative and specific pathologically related features and eventually output more accurate predictions. The superiority of the proposed model lies in its ability to self-generate hybrid features that contain multi-modality image information based on a single-modality input. To evaluate the effectiveness, adaptability, and generalization ability of our model, we performed extensive experiments on a large-scale multi-center dataset (i.e., 829 cases from three hospitals) to compare our model and a series of state-of-the-art (SOTA) classification models. The experimental results demonstrated the superiority of our model for lung cancer subtypes classification with significant accuracy improvements in terms of accuracy (ACC), area under the curve (AUC), and F1 score.

Knowledge tracing (KT) aims to leverage students' learning histories to estimate their mastery levels on a set of pre-defined skills, based on which the corresponding future performance can be accurately predicted. As an important way of providing personalized experience for online education, KT has gained increased attention in recent years. In practice, a student's learning history comprises answers to sets of massed questions, each known as a session, rather than merely being a sequence of independent answers. Theoretically, within and across these sessions, students' learning dynamics can be very different. Therefore, how to effectively model the dynamics of students' knowledge states within and across the sessions is crucial for handling the KT problem. Most existing KT models treat student's learning records as a single continuing sequence, without capturing the sessional shift of students' knowledge state. To address the above issue, we propose a novel hierarchical transformer model, named HiTSKT, comprises an interaction(-level) encoder to capture the knowledge a student acquires within a session, and a session(-level) encoder to summarise acquired knowledge across the past sessions. To predict an interaction in the current session, a knowledge retriever integrates the summarised past-session knowledge with the previous interactions' information into proper knowledge representations. These representations are then used to compute the student's current knowledge state. Additionally, to model the student's long-term forgetting behaviour across the sessions, a power-law-decay attention mechanism is designed and deployed in the session encoder, allowing it to emphasize more on the recent sessions. Extensive experiments on three public datasets demonstrate that HiTSKT achieves new state-of-the-art performance on all the datasets compared with six state-of-the-art KT models.

Recently, discrete latent variable models have received a surge of interest in both Natural Language Processing (NLP) and Computer Vision (CV), attributed to their comparable performance to the continuous counterparts in representation learning, while being more interpretable in their predictions. In this paper, we develop a topic-informed discrete latent variable model for semantic textual similarity, which learns a shared latent space for sentence-pair representation via vector quantization. Compared with previous models limited to local semantic contexts, our model can explore richer semantic information via topic modeling. We further boost the performance of semantic similarity by injecting the quantized representation into a transformer-based language model with a well-designed semantic-driven attention mechanism. We demonstrate, through extensive experiments across various English language datasets, that our model is able to surpass several strong neural baselines in semantic textual similarity tasks.

Medical images, especially volumetric images, are of high resolution and often exceed the capacity of standard desktop GPUs. As a result, most deep learning-based medical image analysis tasks require the input images to be downsampled, often substantially, before these can be fed to a neural network. However, downsampling can lead to a loss of image quality, which is undesirable especially in reconstruction tasks, where the fine geometric details need to be preserved. In this paper, we propose that high-resolution images can be reconstructed in a coarse-to-fine fashion, where a deep learning algorithm is only responsible for generating a coarse representation of the image, which consumes moderate GPU memory. For producing the high-resolution outcome, we propose two novel methods: learned voxel rearrangement of the coarse output and hierarchical image synthesis. Compared to the coarse output, the high-resolution counterpart allows for smooth surface triangulation, which can be 3D-printed in the highest possible quality. Experiments of this paper are carried out on the dataset of AutoImplant 2021 (https://autoimplant2021.grand-challenge.org/), a MICCAI challenge on cranial implant design. The dataset contains high-resolution skulls that can be viewed as 2D manifolds embedded in a 3D space. Codes associated with this study can be accessed at https://github.com/Jianningli/voxel_rearrangement.

The aortic vessel tree is composed of the aorta and its branching arteries, and plays a key role in supplying the whole body with blood. Aortic diseases, like aneurysms or dissections, can lead to an aortic rupture, whose treatment with open surgery is highly risky. Therefore, patients commonly undergo drug treatment under constant monitoring, which requires regular inspections of the vessels through imaging. The standard imaging modality for diagnosis and monitoring is computed tomography (CT), which can provide a detailed picture of the aorta and its branching vessels if combined with a contrast agent, resulting in a CT angiography (CTA). Optimally, the whole aortic vessel tree geometry from consecutive CTAs, are overlaid and compared. This allows to not only detect changes in the aorta, but also more peripheral vessel tree changes, caused by the primary pathology or newly developed. When performed manually, this reconstruction requires slice by slice contouring, which could easily take a whole day for a single aortic vessel tree and, hence, is not feasible in clinical practice. Automatic or semi-automatic vessel tree segmentation algorithms, on the other hand, can complete this task in a fraction of the manual execution time and run in parallel to the clinical routine of the clinicians. In this paper, we systematically review computing techniques for the automatic and semi-automatic segmentation of the aortic vessel tree. The review concludes with an in-depth discussion on how close these state-of-the-art approaches are to an application in clinical practice and how active this research field is, taking into account the number of publications, datasets and challenges.

Federated Learning aims to learn machine learning models from multiple decentralized edge devices (e.g. mobiles) or servers without sacrificing local data privacy. Recent Natural Language Processing techniques rely on deep learning and large pre-trained language models. However, both big deep neural and language models are trained with huge amounts of data which often lies on the server side. Since text data is widely originated from end users, in this work, we look into recent NLP models and techniques which use federated learning as the learning framework. Our survey discusses major challenges in federated natural language processing, including the algorithm challenges, system challenges as well as the privacy issues. We also provide a critical review of the existing Federated NLP evaluation methods and tools. Finally, we highlight the current research gaps and future directions.

Non-negative tensor factorization models enable predictive analysis on count data. Among them, Bayesian Poisson-Gamma models are able to derive full posterior distributions of latent factors and are less sensitive to sparse count data. However, current inference methods for these Bayesian models adopt restricted update rules for the posterior parameters. They also fail to share the update information to better cope with the data sparsity. Moreover, these models are not endowed with a component that handles the imbalance in count data values. In this paper, we propose a novel variational auto-encoder framework called VAE-BPTF which addresses the above issues. It uses multi-layer perceptron networks to encode and share complex update information. The encoded information is then reweighted per data instance to penalize common data values before aggregated to compute the posterior parameters for the latent factors. Under synthetic data evaluation, VAE-BPTF tended to recover the right number of latent factors and posterior parameter values. It also outperformed current models in both reconstruction errors and latent factor (semantic) coherence across five real-world datasets. Furthermore, the latent factors inferred by VAE-BPTF are perceived to be meaningful and coherent under a qualitative analysis.

Online crowdsourcing provides a scalable and inexpensive means to collect knowledge (e.g. labels) about various types of data items (e.g. text, audio, video). However, it is also known to result in large variance in the quality of recorded responses which often cannot be directly used for training machine learning systems. To resolve this issue, a lot of work has been conducted to control the response quality such that low-quality responses cannot adversely affect the performance of the machine learning systems. Such work is referred to as the quality control for crowdsourcing. Past quality control research can be divided into two major branches: quality control mechanism design and statistical models. The first branch focuses on designing measures, thresholds, interfaces and workflows for payment, gamification, question assignment and other mechanisms that influence workers' behaviour. The second branch focuses on developing statistical models to perform effective aggregation of responses to infer correct responses. The two branches are connected as statistical models (i) provide parameter estimates to support the measure and threshold calculation, and (ii) encode modelling assumptions used to derive (theoretical) performance guarantees for the mechanisms. There are surveys regarding each branch but they lack technical details about the other branch. Our survey is the first to bridge the two branches by providing technical details on how they work together under frameworks that systematically unify crowdsourcing aspects modelled by both of them to determine the response quality. We are also the first to provide taxonomies of quality control papers based on the proposed frameworks. Finally, we specify the current limitations and the corresponding future directions for the quality control research.