Evidence-based medicine (EBM) plays a crucial role in the application of large language models (LLMs) in healthcare, as it provides reliable support for medical decision-making processes. Although it benefits from current retrieval-augmented generation~(RAG) technologies, it still faces two significant challenges: the collection of dispersed evidence and the efficient organization of this evidence to support the complex queries necessary for EBM. To tackle these issues, we propose using LLMs to gather scattered evidence from multiple sources and present a knowledge hypergraph-based evidence management model to integrate these evidence while capturing intricate relationships. Furthermore, to better support complex queries, we have developed an Importance-Driven Evidence Prioritization (IDEP) algorithm that utilizes the LLM to generate multiple evidence features, each with an associated importance score, which are then used to rank the evidence and produce the final retrieval results. Experimental results from six datasets demonstrate that our approach outperforms existing RAG techniques in application domains of interest to EBM, such as medical quizzing, hallucination detection, and decision support. Testsets and the constructed knowledge graph can be accessed at \href{https://drive.google.com/file/d/1WJ9QTokK3MdkjEmwuFQxwH96j_Byawj_/view?usp=drive_link}{https://drive.google.com/rag4ebm}.

Cross-hospital collaboration has the potential to address disparities in medical resources across different regions. However, strict privacy regulations prohibit the direct sharing of sensitive patient information between hospitals. Vertical federated learning (VFL) offers a novel privacy-preserving machine learning paradigm that maximizes data utility across multiple hospitals. Traditional VFL methods, however, primarily benefit patients with overlapping data, leaving vulnerable non-overlapping patients without guaranteed improvements in medical prediction services. While some knowledge transfer techniques can enhance the prediction performance for non-overlapping patients, they fall short in addressing scenarios where overlapping and non-overlapping patients belong to different domains, resulting in challenges such as feature heterogeneity and label heterogeneity. To address these issues, we propose a novel unified vertical federated knowledge transfer framework (Unitrans). Our framework consists of three key steps. First, we extract the federated representation of overlapping patients by employing an effective vertical federated representation learning method to model multi-party joint features online. Next, each hospital learns a local knowledge transfer module offline, enabling the transfer of knowledge from the federated representation of overlapping patients to the enriched representation of local non-overlapping patients in a domain-adaptive manner. Finally, hospitals utilize these enriched local representations to enhance performance across various downstream medical prediction tasks. Experiments on real-world medical datasets validate the framework's dual effectiveness in both intra-domain and cross-domain knowledge transfer. The code of \method is available at \url{https://github.com/Chung-ju/Unitrans}.

Weakly supervised temporal action localization (WS-TAL) is a task of targeting at localizing complete action instances and categorizing them with video-level labels. Action-background ambiguity, primarily caused by background noise resulting from aggregation and intra-action variation, is a significant challenge for existing WS-TAL methods. In this paper, we introduce a hybrid multi-head attention (HMHA) module and generalized uncertainty-based evidential fusion (GUEF) module to address the problem. The proposed HMHA effectively enhances RGB and optical flow features by filtering redundant information and adjusting their feature distribution to better align with the WS-TAL task. Additionally, the proposed GUEF adaptively eliminates the interference of background noise by fusing snippet-level evidences to refine uncertainty measurement and select superior foreground feature information, which enables the model to concentrate on integral action instances to achieve better action localization and classification performance. Experimental results conducted on the THUMOS14 dataset demonstrate that our method outperforms state-of-the-art methods. Our code is available in \url{https://github.com/heyuanpengpku/GUEF/tree/main}.

Generally, deep learning has contributed to this field a lot. The most representative deep neural network architectures in computer vision can be roughly divided into transformer-based and CNN-based models. Transformer is originally proposed for natural language processing, which has been transferred to vision tasks and achieves considerably satisfying performance recently. Specifically, vision transformer [1] first introduces attention mechanism into computer vision whose strategy of information interaction enlargers the effective receptive field of related models observably so that crucial information can be better obtained. Due to efficiency of this architecture, the variations of transformer are devised corresponding to specific demands, and there are two main categories in the thoughts about improvements on the variations, namely integration of transformer framework with other models which are for particular usages and modifications on the original architecture. With respect to the former, DS-TransUNet [2] is a typical example, which synthesizes dual transformer-based architectures and U-Net to realize a breakthrough in medical image segmentation. Besides, some works focus on improvements on architecture of transformer, for instance, Mix-ViT [3] tries to design a mix attention mechanism to create more sufficient passages for information interaction.

Language models (LMs) have been widely used to generate text on the Internet. The generated text is often collected into the training corpus of the next generations of LMs. Previous work has experimentally found that LMs collapse when trained on recursively generated text. This paper contributes to existing knowledge from two aspects. We present a theoretical proof of LM collapse. Our proof reveals the cause of LM collapse and proves that all auto-regressive LMs will definitely collapse. We present a new finding: the performance of LMs gradually declines when trained on recursively generated text until they perform no better than a randomly initialized LM. The trained LMs produce large amounts of repetitive text and perform poorly across a wide range of natural language tasks. The above proof and new findings deepen our understanding of LM collapse and offer valuable insights that may inspire new training techniques to mitigate this threat.

This research examines the use of Reinforcement Learning from AI Feedback (RLAIF) techniques to improve healthcare dialogue models, with the aim of tackling the challenges of preference-aligned data annotation while reducing the reliance on medical experts. We argue that the primary challenges in current RLAIF research for healthcare are the limitations of automated evaluation methods and the difficulties in accurately representing physician preferences. To address these challenges, we present a new evaluation framework based on standardized patient examinations. This framework is designed to objectively assess the effectiveness of large language models (LLMs) in guiding users and following instructions, enabling a comprehensive comparison across different models. Furthermore, our investigation of effective ways to express physician preferences using Constitutional AI algorithms highlighted the particular effectiveness of flowcharts. Utilizing this finding, we introduce an innovative agent-based approach for annotating preference data. This approach autonomously creates medical dialogue flows tailored to the patient's condition, demonstrates strong generalization abilities, and reduces the need for expert involvement. Our results show that the agent-based approach outperforms existing RLAIF annotation methods in standardized patient examinations and surpasses current open source medical dialogue LLMs in various test scenarios.

The use of large language models in medical dialogue generation has garnered significant attention, with a focus on improving response quality and fluency. While previous studies have made progress in optimizing model performance for single-round medical Q&A tasks, there is a need to enhance the model's capability for multi-round conversations to avoid logical inconsistencies. To address this, we propose an approach called preference learning from process feedback~(PLPF), which integrates the doctor's diagnostic logic into LLMs. PLPF involves rule modeling, preference data generation, and preference alignment to train the model to adhere to the diagnostic process. Experimental results using Standardized Patient Testing show that PLPF enhances the diagnostic accuracy of the baseline model in medical conversations by 17.6%, outperforming traditional reinforcement learning from human feedback. Additionally, PLPF demonstrates effectiveness in both multi-round and single-round dialogue tasks, showcasing its potential for improving medical dialogue generation.

The modeling of emergent swarm intelligence constitutes a major challenge and it has been tacked in a number of different ways. However, existing approaches fail to capture the nature of swarm intelligence and they are either too abstract for practical application or not generic enough to describe the various types of emergence phenomena. In this paper, a contradiction-centric model for swarm intelligence is proposed, in which individuals determine their behaviors based on their internal contradictions whilst they associate and interact to update their contradictions. The model hypothesizes that 1) the emergence of swarm intelligence is rooted in the development of individuals' internal contradictions and the interactions taking place between individuals and the environment, and 2) swarm intelligence is essentially a combinative reflection of the configurations of individuals' internal contradictions and the distributions of these contradictions across individuals. The model is formally described and five swarm intelligence systems are studied to illustrate its broad applicability. The studies confirm the generic character of the model and its effectiveness for describing the emergence of various kinds of swarm intelligence; and they also demonstrate that the model is straightforward to apply, without the need for complicated computations.