This paper proposes an ultra-low power, mixed-bit-width sparse convolutional neural network (CNN) accelerator to accelerate ventricular arrhythmia (VA) detection. The chip achieves 50% sparsity in a quantized 1D CNN using a sparse processing element (SPE) architecture. Measurement on the prototype chip TSMC 40nm CMOS low-power (LP) process for the VA classification task demonstrates that it consumes 10.60 $\mu$W of power while achieving a performance of 150 GOPS and a diagnostic accuracy of 99.95%. The computation power density is only 0.57 $\mu$W/mm$^2$, which is 14.23X smaller than state-of-the-art works, making it highly suitable for implantable and wearable medical devices.

The scaling laws have become the de facto guidelines for designing large language models (LLMs), but they were studied under the assumption of unlimited computing resources for both training and inference. As LLMs are increasingly used as personalized intelligent assistants, their customization (i.e., learning through fine-tuning) and deployment onto resource-constrained edge devices will become more and more prevalent. An urging but open question is how a resource-constrained computing environment would affect the design choices for a personalized LLM. We study this problem empirically in this work. In particular, we consider the tradeoffs among a number of key design factors and their intertwined impacts on learning efficiency and accuracy. The factors include the learning methods for LLM customization, the amount of personalized data used for learning customization, the types and sizes of LLMs, the compression methods of LLMs, the amount of time afforded to learn, and the difficulty levels of the target use cases. Through extensive experimentation and benchmarking, we draw a number of surprisingly insightful guidelines for deploying LLMs onto resource-constrained devices. For example, an optimal choice between parameter learning and RAG may vary depending on the difficulty of the downstream task, the longer fine-tuning time does not necessarily help the model, and a compressed LLM may be a better choice than an uncompressed LLM to learn from limited personalized data.

Large Language Models (LLMs) deployed on edge devices learn through fine-tuning and updating a certain portion of their parameters. Although such learning methods can be optimized to reduce resource utilization, the overall required resources remain a heavy burden on edge devices. Instead, Retrieval-Augmented Generation (RAG), a resource-efficient LLM learning method, can improve the quality of the LLM-generated content without updating model parameters. However, the RAG-based LLM may involve repetitive searches on the profile data in every user-LLM interaction. This search can lead to significant latency along with the accumulation of user data. Conventional efforts to decrease latency result in restricting the size of saved user data, thus reducing the scalability of RAG as user data continuously grows. It remains an open question: how to free RAG from the constraints of latency and scalability on edge devices? In this paper, we propose a novel framework to accelerate RAG via Computing-in-Memory (CiM) architectures. It accelerates matrix multiplications by performing in-situ computation inside the memory while avoiding the expensive data transfer between the computing unit and memory. Our framework, Robust CiM-backed RAG (RoCR), utilizing a novel contrastive learning-based training method and noise-aware training, can enable RAG to efficiently search profile data with CiM. To the best of our knowledge, this is the first work utilizing CiM to accelerate RAG.

After a large language model (LLM) is deployed on edge devices, it is desirable for these devices to learn from user-generated conversation data to generate user-specific and personalized responses in real-time. However, user-generated data usually contains sensitive and private information, and uploading such data to the cloud for annotation is not preferred if not prohibited. While it is possible to obtain annotation locally by directly asking users to provide preferred responses, such annotations have to be sparse to not affect user experience. In addition, the storage of edge devices is usually too limited to enable large-scale fine-tuning with full user-generated data. It remains an open question how to enable on-device LLM personalization, considering sparse annotation and limited on-device storage. In this paper, we propose a novel framework to select and store the most representative data online in a self-supervised way. Such data has a small memory footprint and allows infrequent requests of user annotations for further fine-tuning. To enhance fine-tuning quality, multiple semantically similar pairs of question texts and expected responses are generated using the LLM. Our experiments show that the proposed framework achieves the best user-specific content-generating capability (accuracy) and fine-tuning speed (performance) compared with vanilla baselines. To the best of our knowledge, this is the very first on-device LLM personalization framework.

The first ACM/IEEE TinyML Design Contest (TDC) held at the 41st International Conference on Computer-Aided Design (ICCAD) in 2022 is a challenging, multi-month, research and development competition. TDC'22 focuses on real-world medical problems that require the innovation and implementation of artificial intelligence/machine learning (AI/ML) algorithms on implantable devices. The challenge problem of TDC'22 is to develop a novel AI/ML-based real-time detection algorithm for life-threatening ventricular arrhythmia over low-power microcontrollers utilized in Implantable Cardioverter-Defibrillators (ICDs). The dataset contains more than 38,000 5-second intracardiac electrograms (IEGMs) segments over 8 different types of rhythm from 90 subjects. The dedicated hardware platform is NUCLEO-L432KC manufactured by STMicroelectronics. TDC'22, which is open to multi-person teams world-wide, attracted more than 150 teams from over 50 organizations. This paper first presents the medical problem, dataset, and evaluation procedure in detail. It further demonstrates and discusses the designs developed by the leading teams as well as representative results. This paper concludes with the direction of improvement for the future TinyML design for health monitoring applications.

Automated acquisition guidance can help novice learners to study how to manipulate probes to acquire high-quality POCUS images. However, the difference between human vision and machine vision may confuse novice learners, because the guidance from sonographers and the DNN model may be inconsistent due to the different interpretations of images between the DNN-based models and humans [6]. For example, DNNs rely more on textures and high-frequency features rather than shapes and low-frequency features. Our previous works show that machine learning based detection methods on medical image can achieve significantly high accuracy [7-15]. This means images considered highquality for humans may not be high-quality for DNN-based machine vision. The discrepancy becomes more significant due to the large inter-observer variability. As a result, if the acquired images are of high quality for both human and DNN-based segmentation models, the segmentation accuracy can be improved, and accordingly, the human efforts needed to correct or identify the bad segmentation can be reduced. As an example in a closely-related area, previous works for medical image compression demonstrated that image compressed with machine vision considered achieved significantly higher segmentation accuracy than conventional methods that only consider human vision at the same compression rate [16]. Therefore, we will explore methods to optimize the image quality assessment and acquisition guidance to be preferred by both human and machine models.

Life-threatening ventricular arrhythmias (VA) are the leading cause of sudden cardiac death (SCD), which is the most significant cause of natural death in the US. The implantable cardioverter defibrillator (ICD) is a small device implanted to patients under high risk of SCD as a preventive treatment. The ICD continuously monitors the intracardiac rhythm and delivers shock when detecting the life-threatening VA. Traditional methods detect VA by setting criteria on the detected rhythm. However, those methods suffer from a high inappropriate shock rate and require a regular follow-up to optimize criteria parameters for each ICD recipient. To ameliorate the challenges, we propose the personalized computing framework for deep learning based VA detection on medical IoT systems. The system consists of intracardiac and surface rhythm monitors, and the cloud platform for data uploading, diagnosis, and CNN model personalization. We equip the system with real-time inference on both intracardiac and surface rhythm monitors. To improve the detection accuracy, we enable the monitors to detect VA collaboratively by proposing the cooperative inference. We also introduce the CNN personalization for each patient based on the computing framework to tackle the unlabeled and limited rhythm data problem. When compared with the traditional detection algorithm, the proposed method achieves comparable accuracy on VA rhythm detection and 6.6% reduction in inappropriate shock rate, while the average inference latency is kept at 71ms.