The Internet of Things (IoT) revolutionizes smart city domains such as healthcare, transportation, industry, and education. The Internet of Medical Things (IoMT) is gaining prominence, particularly in smart hospitals and Remote Patient Monitoring (RPM). The vast volume of data generated by IoMT devices should be analyzed in real-time for health surveillance, prognosis, and prediction of diseases. Current approaches relying on Cloud computing to provide the necessary computing and storage capabilities do not scale for these latency-sensitive applications. Edge computing emerges as a solution by bringing cloud services closer to IoMT devices. This paper introduces SmartEdge, an AI-powered smart healthcare end-to-end integrated edge and cloud computing system for diabetes prediction. This work addresses latency concerns and demonstrates the efficacy of edge resources in healthcare applications within an end-to-end system. The system leverages various risk factors for diabetes prediction. We propose an Edge and Cloud-enabled framework to deploy the proposed diabetes prediction models on various configurations using edge nodes and main cloud servers. Performance metrics are evaluated using, latency, accuracy, and response time. By using ensemble machine learning voting algorithms we can improve the prediction accuracy by 5% versus a single model prediction.

Diabetes Mellitus, one of the leading causes of death worldwide, has no cure to date and can lead to severe health complications, such as retinopathy, limb amputation, cardiovascular diseases, and neuronal disease, if left untreated. Consequently, it becomes crucial to take precautionary measures to avoid/predict the occurrence of diabetes. Machine learning approaches have been proposed and evaluated in the literature for diabetes prediction. This paper proposes an IoT-edge-Artificial Intelligence (AI)-blockchain system for diabetes prediction based on risk factors. The proposed system is underpinned by the blockchain to obtain a cohesive view of the risk factors data from patients across different hospitals and to ensure security and privacy of the user's data. Furthermore, we provide a comparative analysis of different medical sensors, devices, and methods to measure and collect the risk factors values in the system. Numerical experiments and comparative analysis were carried out between our proposed system, using the most accurate random forest (RF) model, and the two most used state-of-the-art machine learning approaches, Logistic Regression (LR) and Support Vector Machine (SVM), using three real-life diabetes datasets. The results show that the proposed system using RF predicts diabetes with 4.57% more accuracy on average compared to LR and SVM, with 2.87 times more execution time. Data balancing without feature selection does not show significant improvement. The performance is improved by 1.14% and 0.02% after feature selection for PIMA Indian and Sylhet datasets respectively, while it reduces by 0.89% for MIMIC III.

The novel coronavirus (COVID-19) was declared as a global pandemic by the World Health Organization (WHO) after it was first discovered in Wuhan, China [1]. Over one year, the virus has infected more than 68 million people worldwide [2]. The virus can be fatal for elderly people or ones with chronic diseases [3]. Different countries across the globe have imposed several social practices and strategies to reduce the spread of the infection and to ensure the well-being of the residents. These practices and strategies include but are not limited to social distancing, restricted and authorized travels, remote work and education, reduced working staff in organizations, and frequent COVID-19 tests. These measures have been proved potential in reducing the disease spread and death in the previous pandemics [3], [4]. Several studies have focused on machine learning time series models to forecast the number of COVID-19 infections in different countries [5, 6, 7, 8, 9, 10, 11, 12, 13, 14]. This is to aid the government in designing and regulating efficient virus spread-mitigating strategies and to enable healthcare organizations for effective planning of health personnel and facilities resources. Based on the forecasted infections, the government can either make the confinement laws stricter or can ease them.

Based on a report by the International Diabetes Federation, in 2021, 537 million adults globally were suffering from diabetes causing 6.7 million deaths [3]. Furthermore, the number of diabetics is projected to reach 643 million by 2030 and 783 million by 2045 [3]. Diabetes in an individual prevails due to a dynamic interaction between different risk factors such as sleep duration, alcohol consumption, dyslipidemia, physical inactivity, serum uric acid, obesity, hypertension, cardiovascular disease, family history of diabetes, ethnicity, depression, age, and gender [4]. If not treated at an early stage, diabetes can lead to severe complications [5]. The use of machine learning has thus gained wide attention for the prediction of diabetes based on risk factors data [6-13] in context of smart healthcare [14,15].