The opioid overdose epidemic remains a critical public health crisis, particularly in the United States, leading to significant mortality and societal costs. Social media platforms like Reddit provide vast amounts of unstructured data that offer insights into public perceptions, discussions, and experiences related to opioid use. This study leverages Natural Language Processing (NLP), specifically Opioid Named Entity Recognition (ONER-2025), to extract actionable information from these platforms. Our research makes four key contributions. First, we created a unique, manually annotated dataset sourced from Reddit, where users share self-reported experiences of opioid use via different administration routes. This dataset contains 331,285 tokens and includes eight major opioid entity categories. Second, we detail our annotation process and guidelines while discussing the challenges of labeling the ONER-2025 dataset. Third, we analyze key linguistic challenges, including slang, ambiguity, fragmented sentences, and emotionally charged language, in opioid discussions. Fourth, we propose a real-time monitoring system to process streaming data from social media, healthcare records, and emergency services to identify overdose events. Using 5-fold cross-validation in 11 experiments, our system integrates machine learning, deep learning, and transformer-based language models with advanced contextual embeddings to enhance understanding. Our transformer-based models (bert-base-NER and roberta-base) achieved 97% accuracy and F1-score, outperforming baselines by 10.23% (RF=0.88).

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by providing a broader perspective than previous studies focused on specific cancer types or applications. Methods: A comprehensive literature search was conducted using the Scopus database, identifying 94 relevant studies published between 2019 and 2024. Data extraction included study characteristics, cancer types, NLP methodologies, dataset information, performance metrics, challenges, and future directions. Studies were categorized based on cancer types and NLP applications. Results: The results showed a growing trend in NLP applications for cancer research, with breast, lung, and colorectal cancers being the most studied. Information extraction and text classification emerged as predominant NLP tasks. A shift from rule-based to advanced machine learning techniques, particularly transformer-based models, was observed. The Dataset sizes used in existing studies varied widely. Key challenges included the limited generalizability of proposed solutions and the need for improved integration into clinical workflows. Conclusion: NLP techniques show significant potential in analyzing EHRs and clinical notes for cancer research. However, future work should focus on improving model generalizability, enhancing robustness in handling complex clinical language, and expanding applications to understudied cancer types. Integration of NLP tools into clinical practice and addressing ethical considerations remain crucial for utilizing the full potential of NLP in enhancing cancer diagnosis, treatment, and patient outcomes.

Medical report generation is the task of automatically writing radiology reports for chest X-ray images. Manually composing these reports is a time-consuming process that is also prone to human errors. Generating medical reports can therefore help reduce the burden on radiologists. In other words, we can promote greater clinical automation in the medical domain. In this work, we propose a new framework leveraging vision-enabled Large Language Models (LLM) for the task of medical report generation. We introduce a lightweight solution that achieves better or comparative performance as compared to previous solutions on the task of medical report generation. We conduct extensive experiments exploring different model sizes and enhancement approaches, such as prefix tuning to improve the text generation abilities of the LLMs. We evaluate our approach on a prominent large-scale radiology report dataset - MIMIC-CXR. Our results demonstrate the capability of our resource-efficient framework to generate patient-specific reports with strong medical contextual understanding and high precision.