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Collaborating Authors

 Du, Lei


Chat2Brain: A Method for Mapping Open-Ended Semantic Queries to Brain Activation Maps

arXiv.org Artificial Intelligence

Over decades, neuroscience has accumulated a wealth of research results in the text modality that can be used to explore cognitive processes. Meta-analysis is a typical method that successfully establishes a link from text queries to brain activation maps using these research results, but it still relies on an ideal query environment. In practical applications, text queries used for meta-analyses may encounter issues such as semantic redundancy and ambiguity, resulting in an inaccurate mapping to brain images. On the other hand, large language models (LLMs) like ChatGPT have shown great potential in tasks such as context understanding and reasoning, displaying a high degree of consistency with human natural language. Hence, LLMs could improve the connection between text modality and neuroscience, resolving existing challenges of meta-analyses. In this study, we propose a method called Chat2Brain that combines LLMs to basic text-2-image model, known as Text2Brain, to map open-ended semantic queries to brain activation maps in data-scarce and complex query environments. By utilizing the understanding and reasoning capabilities of LLMs, the performance of the mapping model is optimized by transferring text queries to semantic queries. We demonstrate that Chat2Brain can synthesize anatomically plausible neural activation patterns for more complex tasks of text queries.


Robust Multi-View Spectral Clustering via Low-Rank and Sparse Decomposition

AAAI Conferences

Multi-view clustering, which seeks a partition of the data inmultiple views that often provide complementary information to eachother, has received considerable attention in recent years. In reallife clustering problems, the data in each view may haveconsiderable noise. However, existing clustering methods blindlycombine the information from multi-view data with possiblyconsiderable noise, which often degrades their performance. In thispaper, we propose a novel Markov chain method for RobustMulti-view Spectral Clustering (RMSC). Our method has a flavor oflow-rank and sparse decomposition, where we firstly construct atransition probability matrix from each single view, and then usethese matrices to recover a shared low-rank transition probabilitymatrix as a crucial input to the standard Markov chain methodfor clustering. The optimization problem of RMSC has a low-rankconstraint on the transition probability matrix, and simultaneouslya probabilistic simplex constraint on each of its rows. To solvethis challenging optimization problem, we propose an optimization procedurebased on the Augmented Lagrangian Multiplier scheme. Experimentalresults on various real world datasets show that theproposed method has superior performance over severalstate-of-the-art methods for multi-view clustering.