The early diagnosis of Alzheimer's Disease (AD) through non invasive methods remains a significant healthcare challenge. We present NeuroXVocal, a novel dual-component system that not only classifies but also explains potential AD cases through speech analysis. The classification component (Neuro) processes three distinct data streams: acoustic features capturing speech patterns and voice characteristics, textual features extracted from speech transcriptions, and precomputed embeddings representing linguistic patterns. These streams are fused through a custom transformer-based architecture that enables robust cross-modal interactions. The explainability component (XVocal) implements a Retrieval-Augmented Generation (RAG) approach, leveraging Large Language Models combined with a domain-specific knowledge base of AD research literature. This architecture enables XVocal to retrieve relevant clinical studies and research findings to generate evidence-based context-sensitive explanations of the acoustic and linguistic markers identified in patient speech. Using the IS2021 ADReSSo Challenge benchmark dataset, our system achieved state-of-the-art performance with 95.77% accuracy in AD classification, significantly outperforming previous approaches. The explainability component was qualitatively evaluated using a structured questionnaire completed by medical professionals, validating its clinical relevance. NeuroXVocal's unique combination of high-accuracy classification and interpretable, literature-grounded explanations demonstrates its potential as a practical tool for supporting clinical AD diagnosis.

This study introduces DK-PRACTICE (Dynamic Knowledge Prediction and Educational Content Recommendation System), an intelligent online platform that leverages machine learning to provide personalized learning recommendations based on student knowledge state. Students participate in a short, adaptive assessment using the question-and-answer method regarding key concepts in a specific knowledge domain. The system dynamically selects the next question for each student based on the correctness and accuracy of their previous answers. After the test is completed, DK-PRACTICE analyzes students' interaction history to recommend learning materials to empower the student's knowledge state in identified knowledge gaps. Both question selection and learning material recommendations are based on machine learning models trained using anonymized data from a real learning environment. To provide self-assessment and monitor learning progress, DK-PRACTICE allows students to take two tests: one pre-teaching and one post-teaching. After each test, a report is generated with detailed results. In addition, the platform offers functions to visualize learning progress based on recorded test statistics. DK-PRACTICE promotes adaptive and personalized learning by empowering students with self-assessment capabilities and providing instructors with valuable information about students' knowledge levels. DK-PRACTICE can be extended to various educational environments and knowledge domains, provided the necessary data is available according to the educational topics. A subsequent paper will present the methodology for the experimental application and evaluation of the platform.

Our proposed framework attempts to break the trade-off between performance and explainability by introducing an explainable-by-design convolutional neural network (CNN) based on the lateral inhibition mechanism. The ExplaiNet model consists of the predictor, that is a high-accuracy CNN with residual or dense skip connections, and the explainer probabilistic graph that expresses the spatial interactions of the network neurons. The value on each graph node is a local discrete feature (LDF) vector, a patch descriptor that represents the indices of antagonistic neurons ordered by the strength of their activations, which are learned with gradient descent. Using LDFs as sequences we can increase the conciseness of explanations by repurposing EXTREME, an EM-based sequence motif discovery method that is typically used in molecular biology. Having a discrete feature motif matrix for each one of intermediate image representations, instead of a continuous activation tensor, allows us to leverage the inherent explainability of Bayesian networks. By collecting observations and directly calculating probabilities, we can explain causal relationships between motifs of adjacent levels and attribute the model's output to global motifs. Moreover, experiments on various tiny image benchmark datasets confirm that our predictor ensures the same level of performance as the baseline architecture for a given count of parameters and/or layers. Our novel method shows promise to exceed this performance while providing an additional stream of explanations. In the solved MNIST classification task, it reaches a comparable to the state-of-the-art performance for single models, using standard training setup and 0.75 million parameters.

We address the problem of predicting the correctness of the student's response on the next exam question based on their previous interactions in the course of their learning and evaluation process. We model the student performance as a dynamic problem and compare the two major classes of dynamic neural architectures for its solution, namely the finite-memory Time Delay Neural Networks (TDNN) and the potentially infinite-memory Recurrent Neural Networks (RNN). Since the next response is a function of the knowledge state of the student and this, in turn, is a function of their previous responses and the skills associated with the previous questions, we propose a two-part network architecture. The first part employs a dynamic neural network (either TDNN or RNN) to trace the student knowledge state. The second part applies on top of the dynamic part and it is a multi-layer feed-forward network which completes the classification task of predicting the student response based on our estimate of the student knowledge state. Both input skills and previous responses are encoded using different embeddings. Regarding the skill embeddings we tried two different initialization schemes using (a) random vectors and (b) pretrained vectors matching the textual descriptions of the skills. Our experiments show that the performance of the RNN approach is better compared to the TDNN approach in all datasets that we have used. Also, we show that our RNN architecture outperforms the state-of-the-art models in four out of five datasets. It is worth noting that the TDNN approach also outperforms the state of the art models in four out of five datasets, although it is slightly worse than our proposed RNN approach. Finally, contrary to our expectations, we find that the initialization of skill embeddings using pretrained vectors offers practically no advantage over random initialization.

Automated sentiment analysis and opinion mining is a complex process concerning the extraction of useful subjective information from text. The explosion of user generated content on the Web, especially the fact that millions of users, on a daily basis, express their opinions on products and services to blogs, wikis, social networks, message boards, etc., render the reliable, automated export of sentiments and opinions from unstructured text crucial for several commercial applications. In this paper, we present a novel hybrid vectorization approach for textual resources that combines a weighted variant of the popular Word2Vec representation (based on Term Frequency-Inverse Document Frequency) representation and with a Bag- of-Words representation and a vector of lexicon-based sentiment values. The proposed text representation approach is assessed through the application of several machine learning classification algorithms on a dataset that is used extensively in literature for sentiment detection. The classification accuracy derived through the proposed hybrid vectorization approach is higher than when its individual components are used for text represenation, and comparable with state-of-the-art sentiment detection methodologies.