Reproducing published deep learning papers to validate their conclusions can be difficult due to sources of irreproducibility. We investigate the impact that implementation factors have on the results and how they affect reproducibility of deep learning studies. Three deep learning experiments were ran five times each on 13 different hardware environments and four different software environments. The analysis of the 780 combined results showed that there was a greater than 6% accuracy range on the same deterministic examples introduced from hardware or software environment variations alone. To account for these implementation factors, researchers should run their experiments multiple times in different hardware and software environments to verify their conclusions are not affected.

Background: Many published machine learning studies are irreproducible. Issues with methodology and not properly accounting for variation introduced by the algorithm themselves or their implementations are attributed as the main contributors to the irreproducibility.Problem: There exist no theoretical framework that relates experiment design choices to potential effects on the conclusions. Without such a framework, it is much harder for practitioners and researchers to evaluate experiment results and describe the limitations of experiments. The lack of such a framework also makes it harder for independent researchers to systematically attribute the causes of failed reproducibility experiments. Objective: The objective of this paper is to develop a framework that enable applied data science practitioners and researchers to understand which experiment design choices can lead to false findings and how and by this help in analyzing the conclusions of reproducibility experiments. Method: We have compiled an extensive list of factors reported in the literature that can lead to machine learning studies being irreproducible. These factors are organized and categorized in a reproducibility framework motivated by the stages of the scientific method. The factors are analyzed for how they can affect the conclusions drawn from experiments. A model comparison study is used as an example. Conclusion: We provide a framework that describes machine learning methodology from experimental design decisions to the conclusions inferred from them.