Human factors engineering studies the interaction between humans and other elements of the systems, aiming to design systems that are more in line with human capabilities and limitations [1]. Human factors engineering originated in the aviation safety field during World War II and gradually expanded into areas such as workstation design, automobile manufacturing, interaction design, and healthcare [2]. Recently, with the development of artificial intelligence (AI), the research scope of human factors engineering is further expanding [3]. Specifically, large multi-modal models (LMMs) have demonstrated significant potential and broad application prospects in various fields such as industrial design and customer service [4], [5]. It is expected that the application of LMMs will gradually change the research paradigm of human factors engineering in three aspects, including human-machine interaction model, research subjects, and research methods.