Whereas conventional state-of-the-art image processing systems of recording and output devices almost exclusively utilize square arranged methods, biological models, however, suggest an alternative, evolutionarily-based structure. Inspired by the human visual perception system, hexagonal image processing in the context of machine learning offers a number of key advantages that can benefit both researchers and users alike. The hexagonal deep learning framework Hexnet leveraged in this contribution serves therefore the generation of hexagonal images by utilizing hexagonal deep neural networks (H-DNN). As the results of our created test environment show, the proposed models can surpass current approaches of conventional image generation. While resulting in a reduction of the models' complexity in the form of trainable parameters, they furthermore allow an increase of test rates in comparison to their square counterparts.

In ophthalmology, intravitreal operative medication therapy (IVOM) is a widespread treatment for diseases related to the age-related macular degeneration (AMD), the diabetic macular edema (DME), as well as the retinal vein occlusion (RVO). However, in real-world settings, patients often suffer from loss of vision on time scales of years despite therapy, whereas the prediction of the visual acuity (VA) and the earliest possible detection of deterioration under real-life conditions is challenging due to heterogeneous and incomplete data. In this contribution, we present a workflow for the development of a research-compatible data corpus fusing different IT systems of the department of ophthalmology of a German maximum care hospital. The extensive data corpus allows predictive statements of the expected progression of a patient and his or her VA in each of the three diseases. We found out for the disease AMD a significant deterioration of the visual acuity over time. Within our proposed multistage system, we classify the VA progression into the three groups of therapy "winners", "stabilizers", and "losers" (WSL scheme). Our OCT biomarker classification using an ensemble of deep neural networks results in a classification accuracy (F1-score) of over 98 %, enabling us to complete incomplete OCT documentations while allowing us to exploit them for a more precise VA modelling process. Our VA prediction requires at least four VA examinations and optionally OCT biomarkers from the same time period to predict the VA progression within a forecasted time frame, whereas our prediction is currently restricted to IVOM / no therapy. While achieving a prediction accuracy of up to 69 % (macro average F1-score) when considering all three WSL-based progression groups, this corresponds to an improvement by 11.2 % in comparison to our ophthalmic expertise (57.8 %).

It is a long-term goal to transfer biological processing principles as well as the power of human recognition into machine vision and engineering systems. One of such principles is visual attention, a smart human concept which focuses processing on a part of a scene. In this contribution, we utilize attention to improve the automatic detection of defect patterns for wafers within the domain of semiconductor manufacturing. Previous works in the domain have often utilized classical machine learning approaches such as KNNs, SVMs, or MLPs, while a few have already used modern approaches like deep neural networks (DNNs). However, one problem in the domain is that the faults are often very small and have to be detected within a larger size of the chip or even the wafer. Therefore, small structures in the size of pixels have to be detected in a vast amount of image data. One interesting principle of the human brain for solving this problem is visual attention. Hence, we employ here a biologically plausible model of visual attention for automatic visual inspection. We propose a hybrid system of visual attention and a deep neural network. As demonstrated, our system achieves among other decisive advantages an improvement in accuracy from 81% to 92%, and an increase in accuracy for detecting faults from 67% to 88%. Hence, the error rates are reduced from 19% to 8%, and notably from 33% to 12% for detecting a fault in a chip. These results show that attention can greatly improve the performance of visual inspection systems. Furthermore, we conduct a broad evaluation, identifying specific advantages of the biological attention model in this application, and benchmarks standard deep learning approaches as an alternative with and without attention. This work is an extended arXiv version of the original conference article published in "IECON 2020", which has been extended regarding visual attention.