Temporally Asymmetric Hebbian Learning, Spike liming and Neural Response Variability

Recent experimental data indicate that the strengthening or weakening of synaptic connections between neurons depends on the relative timing of pre-and postsynaptic action potentials. A Hebbian synaptic modification rule based on these data leads to a stable state in which the excitatory and inhibitory inputs to a neuron are balanced, producing an irregular pattern of firing. It has been proposed that neurons in vivo operate in such a mode.