Deep learning improves prediction of CRISPR–Cpf1 guide RNA activity

These authors contributed equally to this work. H.K.K., M.S., and S.J. performed experiments to build data sets of AsCpf1 indel frequencies. S.M. and S.Y. developed the framework, and carried out the model training and computational validation. Y.K. and S.L. made substantial contributions to the performance of the experiments including cell culture and deep-sequencing. H.H.K. conceived and designed the study.