A Bayesian model for a simulated meta-analysis

#artificialintelligence 

There are multiple ways to estimate a Stan model in R, but I choose to build the Stan code directly rather than using the brms or rstanarm packages. In the Stan code, we need to define the data structure, specify the parameters, specify any transformed parameters (which are just a function of the parameters), and then build the model – which includes laying out the prior distributions as well as the likelihood. In this case, the model is slightly different from what was presented in the context of a mixed effects model. The key difference is that there are prior distributions on \(\Delta\) and \(\tau\), introducing an additional level of uncertainty into the estimate. I would expect that the estimate of the overall treatment effect \(\Delta\) will have a wider 95% CI (credible interval in this context) than the 95% CI (confidence interval) for \(\delta_0\) in the mixed effects model.

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