Fast and Efficient Plastic-Degrading Enzyme Developed Using AI

Plastic waste build-up in the environment is an enormous ecological challenge. Indeed, 40% of plastic waste goes around collection systems and ends up residing in natural environments. Enzymes that break down PET, PET hydrolases, have been previously developed but suffer from practical limitations with slow reaction rates and specific pH and temperature ranges. Now, researchers have used a structure-based, machine learning algorithm to engineer a robust and active PET hydrolase. The enzyme, FAST-PETase (functional, active, stable, and tolerant PETase), can break down environment-throttling plastics that typically take centuries to degrade in just a matter of hours and days.