End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography

D.A., A.P.K., S.B. and B.C. developed the network architecture and data/modeling infrastructure, training and testing setup. D.A. and A.P.K. created the figures, wrote the methods and performed additional analysis requested in the review process. D.P.N. and J.J.R. provided clinical expertise and guidance on the study design. G.C and S.S. advised on the modeling techniques. M.E., S.S., J.J.R., B.C., W.Y. and D.A. created the datasets, interpreted the data and defined the clinical labels.