Spheroids: Research in 3D - Reveal Biosciences

A spheroid is a small, spherical cluster of cells that acts as a 3D cell culture. The term "organoid" is also used interchangeably with "spheroid", although the former specifically refers to a 3D cluster of organ-specific cells. Spheroids and organoids can be artificially assembled through different methods, including the use of centrifugal force or gravity. As the spheroid forms, cells will sort themselves into different regions and layers of the cluster, mimicking natural processes. Cells adhere to each other and exhibit an organic cell shape and architecture.